CA2837926A1 - Scyllo - inositol for the treatment of behavioral and psychiatric disorders - Google Patents

Scyllo - inositol for the treatment of behavioral and psychiatric disorders Download PDF

Info

Publication number
CA2837926A1
CA2837926A1 CA2837926A CA2837926A CA2837926A1 CA 2837926 A1 CA2837926 A1 CA 2837926A1 CA 2837926 A CA2837926 A CA 2837926A CA 2837926 A CA2837926 A CA 2837926A CA 2837926 A1 CA2837926 A1 CA 2837926A1
Authority
CA
Canada
Prior art keywords
inositol
scyllo
dementia
patient
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2837926A
Other languages
English (en)
French (fr)
Inventor
Susan ABUSHAKRA
Gerald CRANS
Jesse Cedarbaum
Ramon Hernandez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transition Therapeutics Ireland Ltd
Original Assignee
Elan Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharmaceuticals LLC filed Critical Elan Pharmaceuticals LLC
Publication of CA2837926A1 publication Critical patent/CA2837926A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2837926A 2011-06-03 2012-06-04 Scyllo - inositol for the treatment of behavioral and psychiatric disorders Abandoned CA2837926A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161520031P 2011-06-03 2011-06-03
US61/520,031 2011-06-03
US201161541333P 2011-09-30 2011-09-30
US61/541,333 2011-09-30
US201261618680P 2012-03-31 2012-03-31
US61/618,680 2012-03-31
PCT/US2012/040789 WO2012173808A1 (en) 2011-06-03 2012-06-04 Scyllo-inositol for the treatment of behavioral and psychiatric disorders

Publications (1)

Publication Number Publication Date
CA2837926A1 true CA2837926A1 (en) 2012-12-20

Family

ID=46298680

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2837926A Abandoned CA2837926A1 (en) 2011-06-03 2012-06-04 Scyllo - inositol for the treatment of behavioral and psychiatric disorders

Country Status (11)

Country Link
US (1) US20140243422A1 (enExample)
EP (1) EP2714050A1 (enExample)
JP (1) JP2014515408A (enExample)
KR (1) KR20140041670A (enExample)
CN (1) CN103906520A (enExample)
AU (1) AU2012271068A1 (enExample)
BR (1) BR112013031117A8 (enExample)
CA (1) CA2837926A1 (enExample)
IL (1) IL229658A0 (enExample)
RU (1) RU2013154699A (enExample)
WO (1) WO2012173808A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
WO2014110234A1 (en) * 2013-01-09 2014-07-17 Elan Pharmaceuticals, Llc Methods of treating developmental and personality disorders
US11191735B2 (en) 2015-03-13 2021-12-07 Nutrition 21, Llc Arginine silicate for periodontal disease
US20170000809A1 (en) * 2015-06-30 2017-01-05 Jds Therapeutics, Llc Arginine silicate inositol for improving cognitive function
WO2017029353A1 (en) * 2015-08-20 2017-02-23 Transition Therapeutics Ireland Limited Treatment of behaviors in dementia patients
US20170135969A1 (en) 2015-11-12 2017-05-18 Jds Therapeutics, Llc Topical arginine-silicate-inositol for wound healing
GB2568849B (en) 2016-09-01 2022-08-10 Nutrition 21 Llc Magnesium biotinate compositions and methods of use
CN113329680A (zh) 2018-11-02 2021-08-31 营养21有限责任公司 用于改善视频游戏者认知功能的含有肌醇稳定的精氨酸硅酸盐复合物和肌醇的组合物
HRP20250882T1 (hr) * 2019-12-02 2025-09-26 Suven Life Sciences Limited Kombinacije masupirdina sa donepezilom ili memantinom za liječenje bihevioralnih i psiholoških simptoma kod pacijenata sa demencijom
BR112022010493A2 (pt) * 2019-12-02 2022-09-06 Suven Life Sciences Ltd Métodos para tratar sintomas comportamentais e psicológicos em pacientes com demência
GB2613672A (en) 2019-12-16 2023-06-14 Nutrition 21 Llc Methods of production of aginine-silicate complexes
EP4583851A1 (en) * 2022-09-07 2025-07-16 EirGen Pharma Ltd. Scyllo-inositol in combination with immunotherapeutics for the treatment of alzheimer's disease
CN115998724B (zh) * 2023-03-28 2023-06-16 中国人民解放军军事科学院军事医学研究院 布洛芬在抗幻觉作用药物中的新用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7521481B2 (en) * 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
IL156203A0 (en) * 2003-05-29 2003-12-23 Yissum Res Dev Co Use of 2,2,3,3, tetramethylcyclopropane carboxylic acid derivatives for treating psychiatric disorders
CA2774930C (en) 2003-10-14 2014-08-05 Hokko Chemical Industry Co., Ltd. Method for producing purified scyllo-inositol utilizing boric acid
CN101505741A (zh) * 2006-03-09 2009-08-12 瓦拉塔药品公司 用于治疗蛋白积聚病症的环己烷多元醇制剂
WO2007101353A1 (en) * 2006-03-09 2007-09-13 Waratah Pharmaceuticals Inc. A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation
US20110201060A1 (en) 2010-02-15 2011-08-18 Abbott Laboratories Process for the preparation of scyllo-inositol
US20150306043A1 (en) * 2012-09-28 2015-10-29 Transition Therapeutics Ireland Limited Combination treatments for bipolar disorders

Also Published As

Publication number Publication date
BR112013031117A8 (pt) 2018-08-14
KR20140041670A (ko) 2014-04-04
WO2012173808A1 (en) 2012-12-20
AU2012271068A1 (en) 2013-12-19
IL229658A0 (en) 2014-01-30
EP2714050A1 (en) 2014-04-09
RU2013154699A (ru) 2015-07-20
CN103906520A (zh) 2014-07-02
US20140243422A1 (en) 2014-08-28
JP2014515408A (ja) 2014-06-30
BR112013031117A2 (pt) 2018-06-19

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20170606