CA2832463A1 - Stimulation devices and methods - Google Patents
Stimulation devices and methods Download PDFInfo
- Publication number
- CA2832463A1 CA2832463A1 CA2832463A CA2832463A CA2832463A1 CA 2832463 A1 CA2832463 A1 CA 2832463A1 CA 2832463 A CA2832463 A CA 2832463A CA 2832463 A CA2832463 A CA 2832463A CA 2832463 A1 CA2832463 A1 CA 2832463A1
- Authority
- CA
- Canada
- Prior art keywords
- microstimulator
- controller
- stimulation
- variations
- signal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37205—Microstimulators, e.g. implantable through a cannula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
- A61N1/37223—Circuits for electromagnetic coupling
- A61N1/37229—Shape or location of the implanted or external antenna
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Electromagnetism (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Electrotherapy Devices (AREA)
- Prostheses (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161473141P | 2011-04-07 | 2011-04-07 | |
| US61/473,141 | 2011-04-07 | ||
| US201161523732P | 2011-08-15 | 2011-08-15 | |
| US61/523,732 | 2011-08-15 | ||
| US13/298,042 US8918181B2 (en) | 2010-11-16 | 2011-11-16 | Systems and methods for treatment of dry eye |
| US13/298,042 | 2011-11-16 | ||
| PCT/US2012/032629 WO2012139063A2 (en) | 2011-04-07 | 2012-04-06 | Stimulation devices and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2832463A1 true CA2832463A1 (en) | 2012-10-11 |
Family
ID=46969854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2832463A Abandoned CA2832463A1 (en) | 2011-04-07 | 2012-04-06 | Stimulation devices and methods |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP2694156B8 (https=) |
| JP (5) | JP6169559B2 (https=) |
| CN (2) | CN105727444B (https=) |
| AU (3) | AU2012239966B2 (https=) |
| BR (1) | BR112013025671A2 (https=) |
| CA (1) | CA2832463A1 (https=) |
| ES (1) | ES2645204T3 (https=) |
| RU (1) | RU2013149420A (https=) |
| WO (1) | WO2012139063A2 (https=) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012068247A1 (en) | 2010-11-16 | 2012-05-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for treatment of dry eye |
| US9821159B2 (en) | 2010-11-16 | 2017-11-21 | The Board Of Trustees Of The Leland Stanford Junior University | Stimulation devices and methods |
| US9265956B2 (en) | 2013-03-08 | 2016-02-23 | Oculeve, Inc. | Devices and methods for treating dry eye in animals |
| EP2967817B1 (en) | 2013-03-12 | 2021-03-10 | Oculeve, Inc. | Implant delivery devices and systems |
| CN105163800B (zh) | 2013-03-14 | 2019-05-14 | 微米器件有限责任公司 | 无线可植入电力接收器系统和方法 |
| NZ704579A (en) | 2013-04-19 | 2018-10-26 | Oculeve Inc | Nasal stimulation devices and methods |
| RU2547960C1 (ru) * | 2014-01-09 | 2015-04-10 | Владимир Александрович Шипилов | Способ лечения глазной поверхности при синдроме "сухого глаза" |
| WO2015130707A2 (en) * | 2014-02-25 | 2015-09-03 | Oculeve, Inc. | Polymer formulations for nasolacrimal stimulation |
| CA2956176A1 (en) | 2014-07-25 | 2016-01-28 | Oculeve, Inc. | Stimulation patterns for treating dry eye |
| GB201414695D0 (en) * | 2014-08-19 | 2014-10-01 | Femeda Ltd | Electrostimulation related devices and methods |
| RU2707167C2 (ru) | 2014-10-22 | 2019-11-22 | Окулив, Инк. | Устройства для стимуляции и способы лечения болезни "сухого глаза" |
| WO2016065213A1 (en) | 2014-10-22 | 2016-04-28 | Oculeve, Inc. | Implantable nasal stimulator systems and methods |
| EP3209370A4 (en) | 2014-10-22 | 2018-05-30 | Oculeve, Inc. | Contact lens for increasing tear production |
| US11291847B2 (en) | 2015-06-16 | 2022-04-05 | The Regents Of The University Of Colorado, A Body Corporate | Systems and methods for preventing, diagnosing, and/or treating one or more medical conditions via neuromodulation |
| WO2016205107A1 (en) * | 2015-06-16 | 2016-12-22 | The Regents Of The University Of Colorado, A Body Corporate | Nasolacrimal implants and related methods for tear stimulation |
| EP3364870B1 (en) * | 2015-10-21 | 2022-09-07 | Neuspera Medical Inc. | Devices and systems for stimulation therapy |
| ITUB20154761A1 (it) * | 2015-10-29 | 2017-04-29 | Resono Ophthalmic S R L | Sistema di elettrodo e relativo dispositivo per il trattamento di patologie dell?occhio, in particolare dell?occhio secco |
| US10426958B2 (en) | 2015-12-04 | 2019-10-01 | Oculeve, Inc. | Intranasal stimulation for enhanced release of ocular mucins and other tear proteins |
| AU2017206728B2 (en) * | 2016-01-12 | 2019-11-21 | Boston Scientific Neuromodulation Corporation | Implantable device programming management |
| US10252048B2 (en) | 2016-02-19 | 2019-04-09 | Oculeve, Inc. | Nasal stimulation for rhinitis, nasal congestion, and ocular allergies |
| US11007367B2 (en) | 2016-03-16 | 2021-05-18 | Nova Oculus Canada Manufacturing Ulc | Microcurrent device for the treatment of visual disease |
| CA3022683A1 (en) | 2016-05-02 | 2017-11-09 | Oculeve, Inc. | Intranasal stimulation for treatment of meibomian gland disease and blepharitis |
| EP3522981A4 (en) * | 2016-10-04 | 2020-06-03 | The Charles Stark Draper Laboratory, Inc. | IMPLANTABLE WIRELESS MICROSTIMULATOR FOR PERIPHERAL NERVES |
| EP3525735B1 (en) * | 2016-10-14 | 2025-07-16 | Olympic Ophthalmics, Inc. | Device for stimulating tear production |
| US12233017B2 (en) | 2016-10-14 | 2025-02-25 | Olympic Ophthalmics, Inc. | Quiet handheld devices and methods for treatment of disorders |
| KR20190124698A (ko) | 2016-12-02 | 2019-11-05 | 오큘레브, 인크. | 건성안 예측 및 치료 권고를 위한 장치 및 방법 |
| CN106861041B (zh) * | 2017-02-21 | 2018-08-31 | 王乐今 | 植入式眼外肌神经肌肉刺激器及其参数设置方法 |
| CN108686301B (zh) * | 2017-04-07 | 2022-02-15 | 林伯刚 | 用于刺激视神经纤维的装置 |
| WO2018232338A1 (en) | 2017-06-16 | 2018-12-20 | AesculaTech, Inc. | Thermoresponsive polymers and uses thereof |
| WO2019034223A1 (en) * | 2017-08-18 | 2019-02-21 | Innocon Medical Aps | SYSTEM FOR ELECTRICAL STIMULATION OF NERFS |
| JP7349154B2 (ja) | 2017-08-18 | 2023-09-22 | イノコン メディカル エーピーエス | 神経の電気刺激のためのシステム |
| TWI667860B (zh) * | 2018-02-09 | 2019-08-01 | Orion Biotech Inc. | 植入式醫材遠距離無線充電強化結構 |
| CN112739410B (zh) * | 2018-09-18 | 2024-10-11 | 威里利生命科学有限责任公司 | 具有连接到颅骨安装包的整体式引线部件的刺激系统 |
| US11395923B2 (en) | 2018-11-16 | 2022-07-26 | Verily Life Sciences Llc | Branched proximal connectors for high density neural interfaces |
| US11376432B2 (en) | 2019-03-26 | 2022-07-05 | Twenty Twenty Therapeutics Llc | Non-invasive periocular device for dry-eye treatment |
| US11298537B2 (en) * | 2019-03-26 | 2022-04-12 | Twenty Twenty Therapeutics Llc | Non-invasive periocular device for dry-eye treatment and closed-loop methods for operating same |
| US12023498B2 (en) * | 2019-07-12 | 2024-07-02 | Biovisics Medical, Inc. | Ocular therapy modes and systems |
| US20250195888A1 (en) * | 2019-12-03 | 2025-06-19 | I-Lumen Scientific, Inc. | Systems, implantable devices and methods for vision related stimulation |
| CN111714793A (zh) * | 2020-05-21 | 2020-09-29 | 温州医科大学附属眼视光医院 | 一种高精度睑板腺诊疗仪 |
| US12310886B2 (en) * | 2020-08-03 | 2025-05-27 | Verily Life Sciences Llc | Ophthalmic devices, systems and methods for treating dry eye |
| DE102020121715B4 (de) * | 2020-08-19 | 2024-01-11 | Mane Biotech UG (haftungsbeschränkt) | Vorrichtung zur Stimulation des Haarwuchses |
| KR102451859B1 (ko) * | 2020-10-12 | 2022-10-11 | 고려대학교 산학협력단 | 3차원 망막 자극 디바이스 |
| CN112386795B (zh) * | 2020-11-18 | 2024-12-31 | 北京大学人民医院 | 一种植入式神经电刺激系统 |
| CN113058155B (zh) * | 2021-03-19 | 2024-09-03 | 中国科学院空天信息创新研究院 | 电引导治疗装置及方法 |
| WO2023076105A1 (en) | 2021-10-25 | 2023-05-04 | Twenty Twenty Therapeutics Llc | Fluid osmolarity sensing and associated systems, devices, and methods |
| US20250281747A1 (en) * | 2024-03-11 | 2025-09-11 | Verily Life Sciences Llc | System, method, and apparatus for underlid home-based meibomian gland disease treatment via resistive heating and magnetic-based mechanical stimulation |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU577549B2 (en) * | 1983-09-14 | 1988-09-29 | Jacob Zabara | Neurocybernetic prothesis |
| WO1994000188A1 (en) * | 1992-06-24 | 1994-01-06 | Cyberonics, Inc. | Treatment of neuropsychiatric disorders by nerve stimulation |
| JP2002519138A (ja) * | 1998-07-06 | 2002-07-02 | アドヴァンスド バイオニクス コーポレイション | 尿失禁治療処置のための移植可能な刺激器システムおよびその方法 |
| WO2000056393A1 (en) * | 1999-03-24 | 2000-09-28 | Second Sight, Llc | Retinal color prosthesis for color sight restoration |
| JP4781576B2 (ja) * | 2001-02-28 | 2011-09-28 | 株式会社ニデック | 眼内埋め込み型視覚刺激装置 |
| EP1372780A4 (en) * | 2001-03-30 | 2006-06-14 | Univ Case Western Reserve | SYSTEMS AND METHODS FOR SELECTIVELY STIMULATING PARTS LOCATED IN THE INTERNAL HATEYER NERVE ON OR NEAR THE NERF, OR FOR SELECTIVE STIMULATION OF NERVE RAMIFICATIONS IN QUESTION TO INDUCE SPECIFIC PHYSIOLOGICAL RESPONSES |
| US6735480B2 (en) * | 2001-06-29 | 2004-05-11 | Abbott Laboratories | Electro-acupuncture device with D-shaped stimulation electrodes |
| US6792312B2 (en) * | 2001-09-06 | 2004-09-14 | Medtronic, Inc. | Connector module having internal weld plates |
| EP1487536A4 (en) * | 2002-03-27 | 2009-12-02 | Cvrx Inc | DEVICES AND METHODS FOR CARDIOVASCULAR REFLEX CONTROL OF COUPLED ELECTRODES |
| US7142909B2 (en) * | 2002-04-11 | 2006-11-28 | Second Sight Medical Products, Inc. | Biocompatible bonding method and electronics package suitable for implantation |
| US20050165458A1 (en) * | 2002-05-09 | 2005-07-28 | Boveja Birinder R. | Method and system to provide therapy for depression using electroconvulsive therapy(ECT) and pulsed electrical stimulation to vagus nerve(s) |
| WO2003101535A1 (en) * | 2002-06-03 | 2003-12-11 | Med-El Elektromedizinische Geraete Gmbh | Implantable device with flexible interconnect to coil |
| JP4242195B2 (ja) * | 2003-04-10 | 2009-03-18 | 俊夫 大城 | 光治療器具 |
| US7571007B2 (en) * | 2004-04-12 | 2009-08-04 | Advanced Neuromodulation Systems, Inc. | Systems and methods for use in pulse generation |
| US7359751B1 (en) * | 2004-05-05 | 2008-04-15 | Advanced Neuromodulation Systems, Inc. | Clinician programmer for use with trial stimulator |
| CA2583404A1 (en) * | 2004-10-20 | 2006-04-27 | Boston Scientific Limited | Leadless cardiac stimulation systems |
| US7555345B2 (en) * | 2005-03-11 | 2009-06-30 | Medtronic, Inc. | Implantable neurostimulator device |
| US7702385B2 (en) * | 2005-11-16 | 2010-04-20 | Boston Scientific Neuromodulation Corporation | Electrode contact configurations for an implantable stimulator |
| US8606362B2 (en) * | 2005-07-08 | 2013-12-10 | Boston Scientific Neuromodulation Corporation | Current output architecture for an implantable stimulator device |
| JP2007044323A (ja) * | 2005-08-11 | 2007-02-22 | Nidek Co Ltd | 視覚再生補助装置 |
| US8005526B2 (en) * | 2005-08-31 | 2011-08-23 | The Regents Of The University Of Michigan | Biologically integrated electrode devices |
| US7729758B2 (en) * | 2005-11-30 | 2010-06-01 | Boston Scientific Neuromodulation Corporation | Magnetically coupled microstimulators |
| US7444181B2 (en) * | 2005-12-14 | 2008-10-28 | Boston Scientific Neuromodulation Corporation | Techniques for sensing and adjusting a compliance voltage in an implantable stimulator device |
| US20070250135A1 (en) * | 2006-04-21 | 2007-10-25 | Bartz-Schmidt Karl U | Compound subretinal prostheses with extra-ocular parts and surgical technique therefore |
| US20070255333A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Neuromodulation therapy for perineal or dorsal branch of pudendal nerve |
| EP2068710A4 (en) * | 2006-09-27 | 2009-10-21 | Huntington Medical Res Inst | APPARATUS AND METHOD FOR TREATING AN OBSTRUCTIVE SLEEP APNEA |
| DE102006048819A1 (de) * | 2006-10-10 | 2008-04-17 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen | Vorrichtung mit einem Grundkörper |
| ES2559058T3 (es) * | 2006-10-18 | 2016-02-10 | Boston Scientific Neuromodulation Corp. | Dispositivo estimulador implantable de múltiples electrodos con un condensador único de desacoplamiento de trayectoria de corriente |
| WO2008101225A2 (en) * | 2007-02-16 | 2008-08-21 | Second Sight Medical Products, Inc. | Flexible circuit electrode array with wire or film support |
| US9592377B2 (en) * | 2007-07-27 | 2017-03-14 | Second Sight Medical Products, Inc. | Implantable device for the brain |
| US8805510B2 (en) * | 2007-08-02 | 2014-08-12 | University of Pittsburgh—of the Commonwealth System of Higher Education | Methods and systems for achieving a physiological response by pudendal nerve stimulation and blockade |
| EP2197536A1 (en) * | 2007-10-09 | 2010-06-23 | Imthera Medical, Inc. | System and method for neural stimulation |
| US8457757B2 (en) * | 2007-11-26 | 2013-06-04 | Micro Transponder, Inc. | Implantable transponder systems and methods |
| US8165694B2 (en) * | 2008-01-29 | 2012-04-24 | Boston Scientific Neuromodulation Corporation | Thermal management of implantable medical devices |
| DE102008002228A1 (de) * | 2008-06-05 | 2009-12-10 | Biotronik Crm Patent Ag | Langgestrecktes Implantat mit externer Energieeinkopplung |
| AU2009308359B2 (en) * | 2008-10-22 | 2014-11-13 | Advanced Neuromodulation Systems, Inc. | Method for processing electrodes for stimulation lead |
| WO2010069317A1 (en) * | 2008-12-19 | 2010-06-24 | Neurodan A/S | Bursts of electrical pulses in the treatment of pelvic disorders by electrical nerve stimulation |
| US8494641B2 (en) * | 2009-04-22 | 2013-07-23 | Autonomic Technologies, Inc. | Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism |
| US9233254B2 (en) * | 2009-02-17 | 2016-01-12 | Boston Scientific Neuromodulation Corporation | Selectable boost converter and charge pump for compliance voltage generation in an implantable stimulator device |
| WO2010123704A2 (en) * | 2009-04-24 | 2010-10-28 | Medtronic, Inc. | Incontinence therapy |
| JP5578540B2 (ja) * | 2009-07-31 | 2014-08-27 | 株式会社ニデック | 視覚再生補助装置及び視覚再生補助装置の製造方法 |
| AU2009222439B2 (en) * | 2009-09-28 | 2011-07-21 | Cochlear Limited | Method and circuitry for measurement and control of stimulation current |
| WO2012068247A1 (en) * | 2010-11-16 | 2012-05-24 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for treatment of dry eye |
-
2012
- 2012-04-06 BR BR112013025671A patent/BR112013025671A2/pt not_active IP Right Cessation
- 2012-04-06 CN CN201610069087.7A patent/CN105727444B/zh not_active Expired - Fee Related
- 2012-04-06 EP EP12768458.7A patent/EP2694156B8/en not_active Not-in-force
- 2012-04-06 CN CN201280028006.9A patent/CN103747834B/zh not_active Expired - Fee Related
- 2012-04-06 RU RU2013149420/14A patent/RU2013149420A/ru not_active Application Discontinuation
- 2012-04-06 AU AU2012239966A patent/AU2012239966B2/en not_active Ceased
- 2012-04-06 WO PCT/US2012/032629 patent/WO2012139063A2/en not_active Ceased
- 2012-04-06 CA CA2832463A patent/CA2832463A1/en not_active Abandoned
- 2012-04-06 JP JP2014504050A patent/JP6169559B2/ja not_active Expired - Fee Related
- 2012-04-06 ES ES12768458.7T patent/ES2645204T3/es active Active
- 2012-04-06 EP EP17167504.4A patent/EP3263175B1/en not_active Not-in-force
-
2016
- 2016-02-26 AU AU2016201224A patent/AU2016201224B2/en not_active Ceased
-
2017
- 2017-06-28 JP JP2017125971A patent/JP6362734B2/ja not_active Expired - Fee Related
-
2018
- 2018-05-08 AU AU2018203202A patent/AU2018203202B2/en not_active Ceased
- 2018-06-26 JP JP2018120583A patent/JP6596124B2/ja not_active Expired - Fee Related
-
2019
- 2019-09-27 JP JP2019176723A patent/JP6746767B2/ja not_active Expired - Fee Related
-
2020
- 2020-08-05 JP JP2020132985A patent/JP2020192343A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP6362734B2 (ja) | 2018-07-25 |
| EP2694156B8 (en) | 2017-08-09 |
| EP3263175B1 (en) | 2021-11-24 |
| EP2694156A4 (en) | 2014-10-01 |
| EP2694156A2 (en) | 2014-02-12 |
| AU2018203202A1 (en) | 2018-05-31 |
| JP6169559B2 (ja) | 2017-07-26 |
| BR112013025671A2 (pt) | 2017-12-12 |
| RU2013149420A (ru) | 2015-05-20 |
| AU2012239966A1 (en) | 2013-05-02 |
| CN105727444A (zh) | 2016-07-06 |
| AU2016201224A1 (en) | 2016-03-24 |
| WO2012139063A3 (en) | 2012-12-27 |
| EP2694156B1 (en) | 2017-06-14 |
| JP2020192343A (ja) | 2020-12-03 |
| JP2017164576A (ja) | 2017-09-21 |
| CN103747834B (zh) | 2016-03-02 |
| JP6596124B2 (ja) | 2019-10-23 |
| JP2014514070A (ja) | 2014-06-19 |
| CN105727444B (zh) | 2018-10-09 |
| JP2018196732A (ja) | 2018-12-13 |
| EP3263175A1 (en) | 2018-01-03 |
| AU2018203202B2 (en) | 2020-10-08 |
| JP6746767B2 (ja) | 2020-08-26 |
| JP2019213969A (ja) | 2019-12-19 |
| AU2012239966B2 (en) | 2015-11-26 |
| AU2016201224B2 (en) | 2018-02-08 |
| WO2012139063A2 (en) | 2012-10-11 |
| ES2645204T3 (es) | 2017-12-04 |
| CN103747834A (zh) | 2014-04-23 |
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| US20250121197A1 (en) | Systems and methods for treatment of dry eye | |
| AU2017204067B2 (en) | Systems and methods for treatment of dry eye |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20170321 |
|
| FZDE | Discontinued |
Effective date: 20230317 |