CN106861041B - 植入式眼外肌神经肌肉刺激器及其参数设置方法 - Google Patents
植入式眼外肌神经肌肉刺激器及其参数设置方法 Download PDFInfo
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- CN106861041B CN106861041B CN201710092691.6A CN201710092691A CN106861041B CN 106861041 B CN106861041 B CN 106861041B CN 201710092691 A CN201710092691 A CN 201710092691A CN 106861041 B CN106861041 B CN 106861041B
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- China
- Prior art keywords
- pulse generator
- extraocular muscle
- implanted
- implantable pulse
- setting
- Prior art date
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- 210000003205 muscle Anatomy 0.000 title claims abstract description 77
- 230000002232 neuromuscular Effects 0.000 title claims abstract description 26
- 238000000034 method Methods 0.000 title claims abstract description 17
- 230000008602 contraction Effects 0.000 claims abstract description 11
- 238000007920 subcutaneous administration Methods 0.000 claims abstract description 9
- 230000000638 stimulation Effects 0.000 claims abstract description 8
- 238000012545 processing Methods 0.000 claims description 22
- 238000007405 data analysis Methods 0.000 claims description 11
- 238000005424 photoluminescence Methods 0.000 claims description 10
- 238000004458 analytical method Methods 0.000 claims description 6
- 238000012546 transfer Methods 0.000 claims description 6
- 230000004118 muscle contraction Effects 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims 1
- 230000005611 electricity Effects 0.000 claims 1
- 206010029864 nystagmus Diseases 0.000 abstract description 18
- 210000005252 bulbus oculi Anatomy 0.000 abstract description 13
- 230000007547 defect Effects 0.000 abstract description 7
- 210000005036 nerve Anatomy 0.000 abstract 2
- 210000001508 eye Anatomy 0.000 description 16
- 238000010586 diagram Methods 0.000 description 6
- 208000015698 cervical squamous intraepithelial neoplasia Diseases 0.000 description 5
- 201000009487 Amblyopia Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000007383 nerve stimulation Effects 0.000 description 4
- 208000006354 Congenital Nystagmus Diseases 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 210000003786 sclera Anatomy 0.000 description 2
- 201000009279 spontaneous ocular nystagmus Diseases 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 210000004279 orbit Anatomy 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 238000004153 renaturation Methods 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36046—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36125—Details of circuitry or electric components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
- A61N1/3752—Details of casing-lead connections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/02—Subjective types, i.e. testing apparatus requiring the active assistance of the patient
- A61B3/08—Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing binocular or stereoscopic vision, e.g. strabismus
- A61B3/085—Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing binocular or stereoscopic vision, e.g. strabismus for testing strabismus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/36139—Control systems using physiological parameters with automatic adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37205—Microstimulators, e.g. implantable through a cannula
Abstract
Description
Claims (10)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710092691.6A CN106861041B (zh) | 2017-02-21 | 2017-02-21 | 植入式眼外肌神经肌肉刺激器及其参数设置方法 |
EP17897519.9A EP3586911B1 (en) | 2017-02-21 | 2017-04-26 | Implantable extraocular muscle neuromuscular stimulator and parameter setting method therefor |
JP2019546319A JP6748308B2 (ja) | 2017-02-21 | 2017-04-26 | 植え込み式眼外筋神経筋刺激装置及びそのパラメータ設定方法 |
PCT/CN2017/081942 WO2018152954A1 (zh) | 2017-02-21 | 2017-04-26 | 植入式眼外肌神经肌肉刺激器及其参数设置方法 |
US16/546,309 US20190374774A1 (en) | 2017-02-21 | 2019-08-21 | Implantable extraocular muscle neuromuscular stimulator and parameter setting method therefor |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710092691.6A CN106861041B (zh) | 2017-02-21 | 2017-02-21 | 植入式眼外肌神经肌肉刺激器及其参数设置方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106861041A CN106861041A (zh) | 2017-06-20 |
CN106861041B true CN106861041B (zh) | 2018-08-31 |
Family
ID=59166496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710092691.6A Active CN106861041B (zh) | 2017-02-21 | 2017-02-21 | 植入式眼外肌神经肌肉刺激器及其参数设置方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20190374774A1 (zh) |
EP (1) | EP3586911B1 (zh) |
JP (1) | JP6748308B2 (zh) |
CN (1) | CN106861041B (zh) |
WO (1) | WO2018152954A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111388189A (zh) * | 2020-03-27 | 2020-07-10 | 王乐今 | 用于降低眼压的引流装置 |
KR102557813B1 (ko) * | 2021-10-13 | 2023-07-19 | 고려대학교 산학협력단 | 마비사시에 적용하기 위한 신경 자극 장치 및 전류 조절 방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090312817A1 (en) * | 2003-11-26 | 2009-12-17 | Wicab, Inc. | Systems and methods for altering brain and body functions and for treating conditions and diseases of the same |
CN100469401C (zh) * | 2005-10-28 | 2009-03-18 | 清华大学 | 一种植入式神经电脉冲刺激系统 |
US20090005756A1 (en) * | 2007-06-29 | 2009-01-01 | Boston Scientific Neuromodulation Corporation | Methods and Systems of Treating Strabismus |
US8352026B2 (en) * | 2007-10-03 | 2013-01-08 | Ethicon, Inc. | Implantable pulse generators and methods for selective nerve stimulation |
US9242094B2 (en) * | 2010-01-12 | 2016-01-26 | The Johns Hopkins University | Implantable vestibular prosthesis |
US9302103B1 (en) * | 2010-09-10 | 2016-04-05 | Cornell University | Neurological prosthesis |
AU2012239966B2 (en) * | 2011-04-07 | 2015-11-26 | Oculeve, Inc. | Stimulation devices and methods |
US20150224318A1 (en) * | 2014-02-12 | 2015-08-13 | Pacesetter, Inc. | Methods and systems for neurostimulation using paddle lead |
-
2017
- 2017-02-21 CN CN201710092691.6A patent/CN106861041B/zh active Active
- 2017-04-26 JP JP2019546319A patent/JP6748308B2/ja active Active
- 2017-04-26 WO PCT/CN2017/081942 patent/WO2018152954A1/zh unknown
- 2017-04-26 EP EP17897519.9A patent/EP3586911B1/en active Active
-
2019
- 2019-08-21 US US16/546,309 patent/US20190374774A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2020508176A (ja) | 2020-03-19 |
US20190374774A1 (en) | 2019-12-12 |
CN106861041A (zh) | 2017-06-20 |
JP6748308B2 (ja) | 2020-08-26 |
WO2018152954A1 (zh) | 2018-08-30 |
EP3586911C0 (en) | 2024-01-03 |
EP3586911A4 (en) | 2021-01-13 |
EP3586911A1 (en) | 2020-01-01 |
EP3586911B1 (en) | 2024-01-03 |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information |
Inventor after: Wang Lejin Inventor after: Meng Xiaoli Inventor after: Dong Jiamei Inventor after: Li Luojia Inventor after: Li Xiaoxin Inventor after: Miao Zequn Inventor after: Guo Lili Inventor after: Lu Yao Inventor after: Huang Lvzhen Inventor after: Zhao Kanxing Inventor after: Huang Ru Inventor after: Ye Le Inventor before: Wang Lejin Inventor before: Miao Zequn Inventor before: Huang Ru Inventor before: Ye Le Inventor before: Lu Yao Inventor before: Meng Xiaoli Inventor before: Guo Lili Inventor before: Dong Jiamei Inventor before: Li Luojia |
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CB03 | Change of inventor or designer information | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20190527 Address after: Room PK4-022, 7th Floor, 36 Haidian West Street, Haidian District, Beijing 100080 Patentee after: Chaomu Technology (Beijing) Co.,Ltd. Address before: 100044 No. 11 South Main Street, Xicheng District, Beijing, Xizhimen Patentee before: Wang Lejin |
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TR01 | Transfer of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Implantable extraocular neuromuscular stimulator and its parameter setting method Effective date of registration: 20210329 Granted publication date: 20180831 Pledgee: Haidian Beijing science and technology enterprise financing Company limited by guarantee Pledgor: Chaomu Technology (Beijing) Co.,Ltd. Registration number: Y2021990000278 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220803 Granted publication date: 20180831 Pledgee: Haidian Beijing science and technology enterprise financing Company limited by guarantee Pledgor: Chaomu Technology (Beijing) Co.,Ltd. Registration number: Y2021990000278 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |