CA2824201A1 - Combination - Google Patents
Combination Download PDFInfo
- Publication number
- CA2824201A1 CA2824201A1 CA2824201A CA2824201A CA2824201A1 CA 2824201 A1 CA2824201 A1 CA 2824201A1 CA 2824201 A CA2824201 A CA 2824201A CA 2824201 A CA2824201 A CA 2824201A CA 2824201 A1 CA2824201 A1 CA 2824201A1
- Authority
- CA
- Canada
- Prior art keywords
- cancer
- methyl
- chloro
- administered
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
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| CA2929715A1 (en) * | 2013-11-07 | 2015-05-14 | Deciphera Pharmaceuticals, Llc | Methods for inhibiting tie2 kinase useful in the treatment of cancer |
| WO2019152711A1 (en) | 2018-01-31 | 2019-08-08 | Diciphera Pharmaceuticals Llc. | Combination therapy for the treatment of gastrointestinal stromal tumors |
| KR102708050B1 (ko) | 2018-01-31 | 2024-09-24 | 데시페라 파마슈티칼스, 엘엘씨. | 비만 세포증의 치료를 위한 병용 요법 |
| TWI878335B (zh) | 2019-08-12 | 2025-04-01 | 美商迪賽孚爾製藥有限公司 | 治療胃腸道基質瘤方法 |
| CA3150433A1 (en) | 2019-08-12 | 2021-02-18 | Deciphera Pharmaceuticals, Llc | Ripretinib for treating gastrointestinal stromal tumors |
| FI4084778T3 (fi) | 2019-12-30 | 2023-12-18 | Deciphera Pharmaceuticals Llc | Amorfisia kinaasi-inhibiittoriformulaatioita ja menetelmiä niiden käyttämiseksi |
| CN115243681B (zh) | 2019-12-30 | 2024-08-16 | 德西费拉制药有限责任公司 | 1-(4-溴-5-(1-乙基-7-(甲氨基)-2-侧氧基-1,2-二氢-1,6-萘啶-3-基)-2-氟苯基)-3-苯基脲的组合物 |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
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-
2012
- 2012-01-11 SG SG10201600077RA patent/SG10201600077RA/en unknown
- 2012-01-11 KR KR1020137021098A patent/KR20140053836A/ko not_active Abandoned
- 2012-01-11 CA CA2824201A patent/CA2824201A1/en not_active Abandoned
- 2012-01-11 BR BR112013017722A patent/BR112013017722A2/pt not_active IP Right Cessation
- 2012-01-11 ES ES12733916.6T patent/ES2689760T3/es active Active
- 2012-01-11 US US13/978,765 patent/US20130288984A1/en not_active Abandoned
- 2012-01-11 EP EP12733916.6A patent/EP2663189B1/en active Active
- 2012-01-11 EA EA201391027A patent/EA029000B1/ru not_active IP Right Cessation
- 2012-01-11 AU AU2012205601A patent/AU2012205601B2/en not_active Ceased
- 2012-01-11 SG SG2013043856A patent/SG191724A1/en unknown
- 2012-01-11 WO PCT/US2012/020863 patent/WO2012097021A1/en not_active Ceased
- 2012-01-11 JP JP2013549503A patent/JP6100700B2/ja active Active
- 2012-01-11 CN CN201280004830.0A patent/CN103298345B/zh active Active
- 2012-01-11 MX MX2013008074A patent/MX356704B/es active IP Right Grant
- 2012-02-08 US US13/368,434 patent/US20120258933A1/en not_active Abandoned
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2013
- 2013-06-06 ZA ZA2013/04139A patent/ZA201304139B/en unknown
- 2013-06-20 IL IL227097A patent/IL227097B/en active IP Right Grant
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2015
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- 2015-08-20 US US14/831,261 patent/US20160022641A1/en not_active Abandoned
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2016
- 2016-09-08 US US15/259,694 patent/US20160375086A1/en not_active Abandoned
- 2016-12-20 US US15/385,205 patent/US10449226B2/en active Active
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|---|---|
| WO2012097021A1 (en) | 2012-07-19 |
| MX2013008074A (es) | 2013-08-09 |
| AU2012205601A1 (en) | 2013-08-01 |
| US20160022641A1 (en) | 2016-01-28 |
| JP2014507412A (ja) | 2014-03-27 |
| AU2012205601B2 (en) | 2016-03-24 |
| ZA201304139B (en) | 2014-02-26 |
| US20150119337A1 (en) | 2015-04-30 |
| EP2663189B1 (en) | 2018-07-04 |
| IL227097B (en) | 2018-02-28 |
| US20160375086A1 (en) | 2016-12-29 |
| CN103298345A (zh) | 2013-09-11 |
| SG10201600077RA (en) | 2016-02-26 |
| EP2663189A4 (en) | 2014-06-11 |
| US20170100449A1 (en) | 2017-04-13 |
| US20120258933A1 (en) | 2012-10-11 |
| KR20140053836A (ko) | 2014-05-08 |
| US20130288984A1 (en) | 2013-10-31 |
| MX356704B (es) | 2018-06-11 |
| EP2663189A1 (en) | 2013-11-20 |
| ES2689760T3 (es) | 2018-11-15 |
| CN103298345B (zh) | 2016-12-14 |
| EA201391027A1 (ru) | 2014-01-30 |
| BR112013017722A2 (pt) | 2016-07-12 |
| SG191724A1 (en) | 2013-08-30 |
| JP6100700B2 (ja) | 2017-03-22 |
| US10449226B2 (en) | 2019-10-22 |
| EA029000B1 (ru) | 2018-01-31 |
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