CA2820718A1 - Metalloenzyme inhibitor compounds - Google Patents
Metalloenzyme inhibitor compounds Download PDFInfo
- Publication number
- CA2820718A1 CA2820718A1 CA2820718A CA2820718A CA2820718A1 CA 2820718 A1 CA2820718 A1 CA 2820718A1 CA 2820718 A CA2820718 A CA 2820718A CA 2820718 A CA2820718 A CA 2820718A CA 2820718 A1 CA2820718 A1 CA 2820718A1
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- CA
- Canada
- Prior art keywords
- compound
- disease
- metalloenzyme
- family
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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- C07—ORGANIC CHEMISTRY
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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Landscapes
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- Neurology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42252810P | 2010-12-13 | 2010-12-13 | |
| US61/422,528 | 2010-12-13 | ||
| PCT/US2011/064658 WO2012082746A2 (en) | 2010-12-13 | 2011-12-13 | Metalloenzyme inhibitor compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2820718A1 true CA2820718A1 (en) | 2012-06-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2820718A Abandoned CA2820718A1 (en) | 2010-12-13 | 2011-12-13 | Metalloenzyme inhibitor compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8669274B2 (https=) |
| EP (1) | EP2651905B1 (https=) |
| JP (1) | JP6071897B2 (https=) |
| KR (1) | KR20130101576A (https=) |
| CN (1) | CN103328452A (https=) |
| AU (1) | AU2011343966B2 (https=) |
| BR (1) | BR112013014484A2 (https=) |
| CA (1) | CA2820718A1 (https=) |
| EA (1) | EA201390876A1 (https=) |
| WO (1) | WO2012082746A2 (https=) |
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| WO2013109998A1 (en) * | 2012-01-20 | 2013-07-25 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
| KR20150087400A (ko) | 2012-11-20 | 2015-07-29 | 버텍스 파마슈티칼스 인코포레이티드 | 인돌아민 2,3-디옥시게나제의 억제제로서 유용한 화합물 |
| AU2014209107B2 (en) | 2013-01-28 | 2018-04-12 | Viamet Pharmaceuticals (NC), Inc. | Metalloenzyme inhibitor compounds |
| DK3888658T3 (da) * | 2015-11-25 | 2024-03-18 | Effector Therapeutics Inc | Eif4-a-inhiberende forbindelser og fremgangsmåder relateret dertil |
| CN114989205A (zh) | 2016-12-22 | 2022-09-02 | 卡里塞拉生物科学股份公司 | 用于抑制精氨酸酶活性的组合物和方法 |
| CN110256342B (zh) * | 2019-07-16 | 2022-06-07 | 河南省科学院化学研究所有限公司 | 一种2-氰基喹啉衍生物的合成方法 |
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| US4227004A (en) * | 1979-01-02 | 1980-10-07 | Ici Americas Inc. | Synthesis of substituted 1-aralkyl-1H-v-triazoles |
| US4921475A (en) | 1983-08-18 | 1990-05-01 | Drug Delivery Systems Inc. | Transdermal drug patch with microtubes |
| US5087240A (en) | 1983-08-18 | 1992-02-11 | Drug Delivery Systems Inc. | Transdermal drug patch with conductive fibers |
| US4738851A (en) | 1985-09-27 | 1988-04-19 | University Of Iowa Research Foundation, Inc. | Controlled release ophthalmic gel formulation |
| US5163899A (en) | 1987-03-20 | 1992-11-17 | Drug Delivery Systems Inc. | Transdermal drug delivery system |
| US5312325A (en) | 1987-05-28 | 1994-05-17 | Drug Delivery Systems Inc | Pulsating transdermal drug delivery system |
| GB8804164D0 (en) | 1988-02-23 | 1988-03-23 | Tucker J M | Bandage for administering physiologically active compound |
| US4882150A (en) | 1988-06-03 | 1989-11-21 | Kaufman Herbert E | Drug delivery system |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| US5088977A (en) | 1988-12-21 | 1992-02-18 | Drug Delivery Systems Inc. | Electrical transdermal drug applicator with counteractor and method of drug delivery |
| US5521222A (en) | 1989-09-28 | 1996-05-28 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
| DK0431519T3 (da) | 1989-12-04 | 1994-07-04 | Searle & Co | System til transdermal indgivelse af albuterol |
| US5077033A (en) | 1990-08-07 | 1991-12-31 | Mediventures Inc. | Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| US5352456A (en) | 1991-10-10 | 1994-10-04 | Cygnus Therapeutic Systems | Device for administering drug transdermally which provides an initial pulse of drug |
| DE69228827T2 (de) | 1991-12-18 | 1999-10-21 | Minnesota Mining And Mfg. Co., Saint Paul | Mehrschichtige sperrstrukturen |
| ATE132381T1 (de) | 1992-01-29 | 1996-01-15 | Voelkl Franz Ski | Ballspielschläger, insbesondere tennisschläger |
| WO1995009157A1 (en) * | 1993-09-30 | 1995-04-06 | Yamanouchi Pharmaceutical Co., Ltd. | Azole derivative and pharmaceutical composition thereof |
| IL114193A (en) | 1994-06-20 | 2000-02-29 | Teva Pharma | Ophthalmic pharmaceutical compositions based on sodium alginate |
| ES2094688B1 (es) | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
| GB9418443D0 (en) * | 1994-09-13 | 1994-11-02 | Pfizer Ltd | Therapeutic agents |
| US5800807A (en) | 1997-01-29 | 1998-09-01 | Bausch & Lomb Incorporated | Ophthalmic compositions including glycerin and propylene glycol |
| US5994335A (en) * | 1997-10-17 | 1999-11-30 | The University Of Maryland, Baltimore | 17-azolyl steroids useful as androgen synthesis inhibitors |
| DE60218493D1 (de) * | 2001-09-12 | 2007-04-12 | Pharmacia & Upjohn Co Llc | Substituierte 7-aza-ä2.2.1übicycloheptane für die behandlung von krankheiten |
| US6770659B2 (en) * | 2002-08-26 | 2004-08-03 | Sk Corporation | Benzoyl piperidine compounds |
| MXPA06000401A (es) * | 2003-07-10 | 2006-03-17 | Osi Pharm Inc | Derivados de naftileno como inhibidores de citocromo p450. |
| GB2404613A (en) | 2003-07-14 | 2005-02-09 | David Jarman | A vegetation pruning device |
| CN1993347A (zh) * | 2004-07-29 | 2007-07-04 | 默克公司 | 钾通道抑制剂 |
| US7183284B2 (en) * | 2004-12-29 | 2007-02-27 | Bristol-Myers Squibb Company | Aminium salts of 1,2,3-triazoles as prodrugs of drugs including antiviral agents |
| CL2007002231A1 (es) * | 2006-08-02 | 2008-04-11 | Basf Ag | Uso de compuestos derivados de 5-(het) arilpirimidina para combatir hongos daninos; compuestos derivados de 5-(het) arilpirimidina; agente fungicida; y agente farmaceutico. |
| JP2011517313A (ja) | 2007-12-11 | 2011-06-02 | ビアメト ファーマシューティカルズ，インク． | 金属結合部分を標的化部分と組み合わせて使用する金属酵素阻害剤 |
| US8101642B2 (en) | 2008-06-05 | 2012-01-24 | Sk Biopharmaceuticals Co., Ltd. | 3-substituted propanamine compounds |
| JP5527668B2 (ja) | 2008-06-05 | 2014-06-18 | エスケー バイオファーマスティカルズ カンパニー リミテッド | ３−置換プロパンアミン化合物 |
| US8546576B2 (en) | 2008-06-06 | 2013-10-01 | Sk Biopharmaceuticals Co., Ltd. | 3 or 4-substituted piperidine compounds |
-
2011
- 2011-12-13 CN CN201180065056XA patent/CN103328452A/zh active Pending
- 2011-12-13 CA CA2820718A patent/CA2820718A1/en not_active Abandoned
- 2011-12-13 US US13/324,707 patent/US8669274B2/en not_active Expired - Fee Related
- 2011-12-13 JP JP2013543412A patent/JP6071897B2/ja not_active Expired - Fee Related
- 2011-12-13 EA EA201390876A patent/EA201390876A1/ru unknown
- 2011-12-13 WO PCT/US2011/064658 patent/WO2012082746A2/en not_active Ceased
- 2011-12-13 EP EP11848545.7A patent/EP2651905B1/en not_active Not-in-force
- 2011-12-13 KR KR1020137017838A patent/KR20130101576A/ko not_active Ceased
- 2011-12-13 AU AU2011343966A patent/AU2011343966B2/en not_active Ceased
- 2011-12-13 BR BR112013014484A patent/BR112013014484A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012082746A2 (en) | 2012-06-21 |
| KR20130101576A (ko) | 2013-09-13 |
| EP2651905B1 (en) | 2017-07-19 |
| EP2651905A2 (en) | 2013-10-23 |
| JP2014504287A (ja) | 2014-02-20 |
| AU2011343966B2 (en) | 2017-03-16 |
| CN103328452A (zh) | 2013-09-25 |
| JP6071897B2 (ja) | 2017-02-01 |
| AU2011343966A1 (en) | 2013-07-04 |
| WO2012082746A3 (en) | 2012-08-30 |
| US8669274B2 (en) | 2014-03-11 |
| US20120149729A1 (en) | 2012-06-14 |
| BR112013014484A2 (pt) | 2016-07-19 |
| EA201390876A1 (ru) | 2013-12-30 |
| EP2651905A4 (en) | 2014-05-07 |
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| EEER | Examination request |
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| FZDE | Discontinued |
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