CA2814212C - Nasal spray device - Google Patents

Nasal spray device Download PDF

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Publication number
CA2814212C
CA2814212C CA2814212A CA2814212A CA2814212C CA 2814212 C CA2814212 C CA 2814212C CA 2814212 A CA2814212 A CA 2814212A CA 2814212 A CA2814212 A CA 2814212A CA 2814212 C CA2814212 C CA 2814212C
Authority
CA
Canada
Prior art keywords
discharge orifice
nasal spray
spray device
pharmaceutical formulation
aerosol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2814212A
Other languages
English (en)
French (fr)
Other versions
CA2814212A1 (en
Inventor
Declan Walsh
Xian-Ming Zeng
Jade Ly
Armando Morales
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ivax Pharmaceuticals Ireland
Teva Branded Pharmaceutical Products R&D Inc
Original Assignee
Ivax Pharmaceuticals Ireland
Teva Branded Pharmaceutical Products R&D Inc
Ivax Research LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44907783&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2814212(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ivax Pharmaceuticals Ireland, Teva Branded Pharmaceutical Products R&D Inc, Ivax Research LLC filed Critical Ivax Pharmaceuticals Ireland
Publication of CA2814212A1 publication Critical patent/CA2814212A1/en
Application granted granted Critical
Publication of CA2814212C publication Critical patent/CA2814212C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/08Inhaling devices inserted into the nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/44Valves specially adapted for the discharge of contents; Regulating devices
    • B65D83/52Metering valves; Metering devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Massaging Devices (AREA)
CA2814212A 2010-10-12 2011-10-12 Nasal spray device Active CA2814212C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39222310P 2010-10-12 2010-10-12
US61/392,223 2010-10-12
PCT/EP2011/005118 WO2012048867A1 (en) 2010-10-12 2011-10-12 Nasal spray device

Publications (2)

Publication Number Publication Date
CA2814212A1 CA2814212A1 (en) 2012-04-19
CA2814212C true CA2814212C (en) 2015-06-02

Family

ID=44907783

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2814212A Active CA2814212C (en) 2010-10-12 2011-10-12 Nasal spray device

Country Status (29)

Country Link
US (2) US20120085345A1 (enExample)
EP (2) EP2627386B1 (enExample)
JP (2) JP6050236B2 (enExample)
KR (1) KR101559639B1 (enExample)
CN (3) CN106178205A (enExample)
AU (1) AU2011316124B2 (enExample)
BR (1) BR112013008824A2 (enExample)
CA (1) CA2814212C (enExample)
CL (1) CL2013000958A1 (enExample)
CY (1) CY1121719T1 (enExample)
DK (2) DK2926855T3 (enExample)
EA (1) EA023795B1 (enExample)
ES (2) ES2536969T3 (enExample)
HR (2) HRP20150452T1 (enExample)
HU (1) HUE043276T2 (enExample)
IL (1) IL225712A (enExample)
LT (1) LT2926855T (enExample)
MX (1) MX336164B (enExample)
NZ (1) NZ608218A (enExample)
PE (1) PE20131492A1 (enExample)
PL (2) PL2926855T3 (enExample)
PT (2) PT2627386E (enExample)
RS (2) RS58574B1 (enExample)
SG (1) SG189892A1 (enExample)
SI (2) SI2926855T1 (enExample)
SM (2) SMT201900135T1 (enExample)
TR (1) TR201902415T4 (enExample)
WO (1) WO2012048867A1 (enExample)
ZA (1) ZA201301938B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201121812D0 (en) * 2011-12-07 2012-02-01 Teva Branded Pharmaceutical Prod R & D Inc NAsal formulation
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
KR20150048727A (ko) * 2012-08-29 2015-05-07 키에시 파르마슈티시 엣스. 피. 에이. 에어로졸 흡입 장치
GB201308679D0 (en) * 2013-05-14 2013-06-26 3M Innovative Properties Co Actuator for an inhaler
CN103550058B (zh) * 2013-11-21 2015-08-19 江门大诚医疗器械有限公司 一种加氧清创器
GB201322677D0 (en) * 2013-12-20 2014-02-05 3M Innovative Properties Co Actuator for an inhaler
GB201408229D0 (en) * 2014-05-09 2014-06-25 Norton Waterford Ltd Aerosol device
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
WO2017008127A1 (en) * 2015-07-16 2017-01-19 Gd Pharma Pty Ltd Spray device and dosage cartridge
CN106376976B (zh) * 2016-10-13 2023-05-12 深圳市新宜康科技股份有限公司 一种单侧气道油气分离电子烟雾化器
KR102274992B1 (ko) * 2016-11-06 2021-07-12 마이크로 베이스 테크놀로지 코퍼레이션 고압액체 전송에 적용되는 장치
US10556072B2 (en) * 2017-01-31 2020-02-11 Dunan Microstaq, Inc. Metering device for a metered dose inhaler
KR102140739B1 (ko) 2018-04-23 2020-08-04 충남대학교산학협력단 상기도 분무 장치
US12133845B2 (en) * 2018-10-08 2024-11-05 Troikaa Pharmaceuticals Limited Oromucosal solutions of zolpidem or pharmaceutically acceptable salts thereof
KR20200098188A (ko) 2019-02-12 2020-08-20 조민수 다기능 상기도 분무 장치
CN210123827U (zh) * 2019-05-31 2020-03-03 庆虹电子(苏州)有限公司 电连接器
WO2021247283A1 (en) * 2020-06-04 2021-12-09 Amcyte Pharma, Inc. Delivery of aerosolized micromolar composition concentrations
US20220054668A1 (en) * 2020-08-21 2022-02-24 Carefusion 2200, Inc. Lavage fluid delivery device and systems
FR3120534B1 (fr) * 2021-03-09 2023-06-30 Aptar France Sas Tête de distribution nasale de produit fluide et dispositif comportant une telle tête
CN117083054A (zh) * 2021-03-23 2023-11-17 1232176 B.C.有限公司 用于治疗过敏反应的装置
WO2024079676A1 (en) * 2022-10-12 2024-04-18 Glenmark Specialty S.A. Novel nasal spray assembling process
CN116688331B (zh) * 2023-05-29 2024-02-20 山东京卫制药有限公司 一种鼻气雾剂给药器及其方法
CN116902402A (zh) * 2023-08-14 2023-10-20 中山市美捷时包装制品有限公司 一种气雾剂阀门及气雾剂喷雾装置
GB2639064A (en) * 2023-08-14 2025-09-10 Majesty Holdings Co Ltd Aerosol valve and aerosol sprayer

Family Cites Families (22)

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US3361306A (en) * 1966-03-31 1968-01-02 Merck & Co Inc Aerosol unit dispensing uniform amounts of a medically active ingredient
SE8704767L (sv) * 1987-11-30 1989-05-31 Sigmund Johannes Loefstedt Ny metod foer administrering av laekemedel
JP2922935B2 (ja) * 1989-08-11 1999-07-26 東興薬品工業株式会社 粘稠液用鼻孔内噴霧容器の使捨てアダプタ
CA2094266C (en) 1990-10-18 1999-06-01 Robert K. Schultz Aerosol formulations of beclomethasone-17,21-dipropionate
GB9705657D0 (en) * 1997-03-19 1997-05-07 Bacon Raymond J Dispenser
GB9805938D0 (en) 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
GB0121568D0 (en) * 2001-09-06 2001-10-24 Optinose As Nasal delivery device
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
GB0002798D0 (en) * 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
JP4472105B2 (ja) * 2000-04-20 2010-06-02 株式会社ダイゾー 噴霧製品
GB2367011A (en) * 2000-08-26 2002-03-27 Glaxo Group Ltd Metered dose inhaler for salmeterol
US20030178022A1 (en) * 2001-12-21 2003-09-25 Chiesi Farmaceutici S.P.A. Pressurized metered dose inhaler (PMDI) actuators and medicinal aerosol solution formulation products comprising therse actuators
GB0226020D0 (en) 2002-11-07 2002-12-18 Glaxo Group Ltd A holder
US7448385B2 (en) * 2004-06-07 2008-11-11 Purepharm Inc. Nasal adaptation of an oral inhaler device
US7055541B2 (en) 2004-09-07 2006-06-06 Ramot At Tel-Aviv University Ltd. Method and mechanism for producing suction and periodic excitation flow
FR2881119B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
EP1792660A1 (en) * 2005-12-02 2007-06-06 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
CN101528290A (zh) * 2006-08-22 2009-09-09 葛兰素集团有限公司 用于吸入器的致动器
JP5330994B2 (ja) * 2006-08-22 2013-10-30 グラクソ グループ リミテッド 吸入器用のアクチュエータ
MX2009009061A (es) * 2007-02-28 2009-11-12 Abbott Respiratory Llc Sistema de atomizacion a base de boquilla.
EP2011534A1 (en) 2007-07-03 2009-01-07 CHIESI FARMACEUTICI S.p.A. Metered dose inhaler actuator
DE102007063213B3 (de) * 2007-12-20 2009-06-18 Ing. Erich Pfeiffer Gmbh Austragsvorrichtung zur nasalen Anwendung

Also Published As

Publication number Publication date
MX2013003840A (es) 2013-08-15
JP2013541378A (ja) 2013-11-14
EA023795B1 (ru) 2016-07-29
SMT201900135T1 (it) 2019-05-10
CN106178206A (zh) 2016-12-07
KR101559639B1 (ko) 2015-10-12
RS54037B1 (sr) 2015-10-30
SI2926855T1 (sl) 2019-05-31
ES2536969T3 (es) 2015-06-01
US10188811B2 (en) 2019-01-29
PT2627386E (pt) 2015-06-11
PT2926855T (pt) 2019-02-27
CL2013000958A1 (es) 2014-05-30
HK1214990A1 (en) 2016-08-12
JP6050236B2 (ja) 2016-12-21
ES2712996T3 (es) 2019-05-17
LT2926855T (lt) 2019-03-25
CA2814212A1 (en) 2012-04-19
SG189892A1 (en) 2013-06-28
PE20131492A1 (es) 2014-01-17
IL225712A (en) 2017-07-31
NZ608218A (en) 2014-10-31
PL2926855T3 (pl) 2019-06-28
HUE043276T2 (hu) 2019-08-28
ZA201301938B (en) 2014-05-28
CY1121719T1 (el) 2020-07-31
CN106178205A (zh) 2016-12-07
EP2926855A1 (en) 2015-10-07
MX336164B (es) 2016-01-11
WO2012048867A1 (en) 2012-04-19
SMT201500114B (it) 2015-09-07
EA201390490A1 (ru) 2013-07-30
PL2627386T3 (pl) 2015-08-31
KR20130100334A (ko) 2013-09-10
SI2627386T1 (sl) 2015-10-30
DK2627386T3 (en) 2015-05-26
EP2627386B1 (en) 2015-04-22
DK2926855T3 (en) 2019-03-25
EP2627386A1 (en) 2013-08-21
AU2011316124B2 (en) 2014-12-11
AU2011316124A1 (en) 2013-04-04
US20120085345A1 (en) 2012-04-12
HRP20190337T1 (hr) 2019-05-03
CN103282070A (zh) 2013-09-04
EP2926855B1 (en) 2018-12-05
HRP20150452T1 (hr) 2015-08-14
IL225712A0 (en) 2013-06-27
JP6023247B2 (ja) 2016-11-09
CN103282070B (zh) 2016-08-10
TR201902415T4 (tr) 2019-03-21
RS58574B1 (sr) 2019-05-31
BR112013008824A2 (pt) 2016-06-28
JP2015147061A (ja) 2015-08-20
US20160082204A1 (en) 2016-03-24

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Legal Events

Date Code Title Description
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Effective date: 20130410