CA2812599A1 - Simple adhesive coacervates and methods of making and using thereof - Google Patents

Simple adhesive coacervates and methods of making and using thereof Download PDF

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Publication number
CA2812599A1
CA2812599A1 CA2812599A CA2812599A CA2812599A1 CA 2812599 A1 CA2812599 A1 CA 2812599A1 CA 2812599 A CA2812599 A CA 2812599A CA 2812599 A CA2812599 A CA 2812599A CA 2812599 A1 CA2812599 A1 CA 2812599A1
Authority
CA
Canada
Prior art keywords
adhesive
group
substrate
polycation
coacervate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2812599A
Other languages
English (en)
French (fr)
Inventor
Russell J. Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah Research Foundation Inc
Original Assignee
University of Utah Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah Research Foundation Inc filed Critical University of Utah Research Foundation Inc
Publication of CA2812599A1 publication Critical patent/CA2812599A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J143/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing boron, silicon, phosphorus, selenium, tellurium, or a metal; Adhesives based on derivatives of such polymers
    • C09J143/02—Homopolymers or copolymers of monomers containing phosphorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/28—Web or sheet containing structurally defined element or component and having an adhesive outermost layer
    • Y10T428/2852—Adhesive compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Dental Preparations (AREA)
  • Surgical Instruments (AREA)
  • Adhesive Tapes (AREA)
CA2812599A 2010-11-12 2011-11-12 Simple adhesive coacervates and methods of making and using thereof Abandoned CA2812599A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41283410P 2010-11-12 2010-11-12
US61/412,834 2010-11-12
PCT/US2011/060500 WO2012065148A2 (en) 2010-11-12 2011-11-12 Simple adhesive coacervates and methods of making and using thereof

Publications (1)

Publication Number Publication Date
CA2812599A1 true CA2812599A1 (en) 2012-05-18

Family

ID=45094250

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2812599A Abandoned CA2812599A1 (en) 2010-11-12 2011-11-12 Simple adhesive coacervates and methods of making and using thereof

Country Status (7)

Country Link
US (3) US9173971B2 (enExample)
EP (1) EP2637708A2 (enExample)
JP (1) JP2014502296A (enExample)
CN (1) CN103179992A (enExample)
AU (1) AU2011325961A1 (enExample)
CA (1) CA2812599A1 (enExample)
WO (1) WO2012065148A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9814778B2 (en) 2014-03-06 2017-11-14 The University Of Toledo Ionically crosslinked polyelectrolytes as underwater adhesives as controlled release vehicles

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2712843A1 (en) 2008-01-24 2009-07-30 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
US8283384B2 (en) 2008-01-24 2012-10-09 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
US20110287067A1 (en) 2010-05-24 2011-11-24 University Of Utah Research Foundation Reinforced adhesive complex coacervates and methods of making and using thereof
AU2011325961A1 (en) 2010-11-12 2013-03-28 University Of Utah Research Foundation Simple adhesive coacervates and methods of making and using thereof
US20130273145A1 (en) * 2012-03-06 2013-10-17 Kci Licensing, Inc. Compositions, the preparation and use thereof
WO2014123665A1 (en) 2013-02-06 2014-08-14 Kci Licensing, Inc. Polymers, preparation and use thereof
CN103242762A (zh) * 2013-05-31 2013-08-14 苏州华周胶带有限公司 一种以环氧薄膜为基材的胶带的制造方法
EP3079730B1 (en) * 2013-12-10 2023-02-01 INSERM - Institut National de la Santé et de la Recherche Médicale Methods for adhering tissue surfaces and materials and biomedical uses thereof
EP3632478B1 (en) * 2014-07-14 2022-09-28 University of Utah Research Foundation In situ solidifying solution and methods of making and using thereof
CN105770983B (zh) * 2016-03-14 2019-02-19 武汉纺织大学 一种透明质酸生物粘合剂的制备方法
WO2017172955A1 (en) 2016-03-29 2017-10-05 Safewhite, Inc. Polyelectrolyte dental adhesives for whitening teeth and teeth components
CN106798952B (zh) * 2017-02-13 2019-12-10 先健科技(深圳)有限公司 可吸收铁基骨折内固定材料
EP3687479A4 (en) * 2017-09-29 2021-07-14 SafeWhite, Inc. POLYELECTROLYTE DENTAL COATINGS
WO2019070561A1 (en) * 2017-10-02 2019-04-11 Aleo Bme, Inc. ADHESIVES FOR WATER-BASED FABRICS
WO2019084548A1 (en) * 2017-10-27 2019-05-02 University Of Utah Research Foundation COMPLEX LIQUID IN SITU SOLIDIFICATION COASTALITIES FOR LOCAL ADMINISTRATION OF ANTI-ANGIOGENIC AGENTS OR CHEMOTHERAPEUTIC AGENTS
JP7410876B2 (ja) 2018-01-26 2024-01-10 フルイデックス メディカル テクノロジー，リミティッド ライアビリティ カンパニー 血管閉塞のためにその場凝固複合コアセルベートを使用する装置及び方法
CN108186371B (zh) * 2018-02-05 2020-09-22 上海御齿台医疗科技有限公司 安全种植牙用粘合剂及其制备方法
CN109453144A (zh) * 2019-01-04 2019-03-12 巴斯特医药科技（常州）有限公司 具有可膨润性低密度网传输槽的长效控释复合膜及其制法
DE102019109150A1 (de) * 2019-04-08 2020-10-08 Mühlbauer Technology Gmbh Remineralisierendes Dentalmaterial
DE102020124372A1 (de) * 2020-09-18 2022-03-24 Carl Zeiss Meditec Ag Gewebekleber zur Anwendung in einem Behandlungsverfahren, bei welchem einem menschlichen oder tierischen Patienten ein ophthalmologisches Implantat implantiert wird, und ophthalmologisches Implantationssystem
CN114533944A (zh) * 2022-03-01 2022-05-27 袁淑惠 一种基于天然化合物的弹性体组织密封胶及其制备方法
FR3135475B1 (fr) 2022-05-12 2025-03-21 Saint Gobain Adfors Revêtement mural préencollé avec une composition adhésive latente activable à l’eau
EP4299680A1 (en) 2022-06-29 2024-01-03 Saint-Gobain Weber France Quick setting aqueous composition comprising polyelectrolyte coacervates and polyphenols
CN114939192B (zh) * 2022-07-01 2023-05-12 郑州大学第一附属医院 一种巩膜钉用水凝胶及其制备方法和应用
EP4634448A1 (fr) 2022-12-16 2025-10-22 Saint-Gobain Adfors Textile lié par un liant à base de polyélectrolytes à polarités de charge opposees
FR3145939B1 (fr) 2023-02-21 2025-03-21 Saint Gobain Isover Amélioration de l’adhésion entre l’isolant et l’enduit dans des systèmes d’isolation thermique par l’extérieur de bâtiments

Family Cites Families (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3456460A (en) 1967-04-11 1969-07-22 Singer Co Cylinder and dial knitting machine
US3458460A (en) 1967-11-27 1969-07-29 Hooker Chemical Corp Unsaturated polyesters cross-linked by diels-alder reaction
US3950296A (en) 1972-04-28 1976-04-13 The Dow Chemical Company Reversible coacervation of anion-containing aqueous disperse systems with amphoteric polyelectrolytes
US3947396A (en) 1972-04-28 1976-03-30 The Dow Chemical Company Coacervation of anion-containing aqueous disperse systems with amphoteric polyelectrolytes
US4767463A (en) 1987-04-15 1988-08-30 Union Carbide Corporation Glycosaminoglycan and cationic polymer combinations
US4913743A (en) 1987-04-15 1990-04-03 Biomatrix, Inc. Processes for managing keratinous material using glycosaminoglycan and cationic polymer combinations
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
TW328535B (en) 1993-07-02 1998-03-21 Novartis Ag Functional photoinitiators and their manufacture
WO1995003789A1 (en) * 1993-07-28 1995-02-09 The Johns Hopkins University School Of Medicine Controlled release of pharmaceutically active substances from coacervate microcapsules
AU7634694A (en) 1993-08-20 1995-03-21 University Of Medicine And Dentistry Of New Jersey Bridged polycationic polymer-oligonucleotide conjugates and methods for preparing same
JPH11505505A (ja) * 1994-06-27 1999-05-21 ザ・ジョンズ・ホプキンス・ユニバーシティー ターゲッティングされた遺伝子輸送システム
AU3739697A (en) * 1996-07-09 1998-02-02 Johns Hopkins University, The Gene delivery system
AU7121198A (en) * 1997-04-18 1998-11-13 California Institute Of Technology Multifunctional polymeric tissue coatings
AU749032B2 (en) * 1997-06-13 2002-06-20 Johns Hopkins University, The Therapeutic nanospheres
DE19810965A1 (de) 1998-03-13 1999-09-16 Aventis Res & Tech Gmbh & Co Nanopartikel, Verfahren zu ihrer Herstellung und ihre Verwendung
US6428978B1 (en) 1998-05-08 2002-08-06 Cohesion Technologies, Inc. Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
EP1130996B1 (en) * 1998-11-20 2005-04-13 The University of Connecticut Generic integrated implantable potentiostat telemetry unit for electrochemical sensors
BR0007644A (pt) * 1999-01-22 2002-01-08 St Jude Medical Compósito de componentes de substrato/adesivo, método de prender um primeiro substrato a um segundo substrato, sistema de ligação, método de preparar um primeiro substrato para ligação a um segundo substrato, substrato, métodos de formar um substrato e de formar uma prótese
US6312725B1 (en) 1999-04-16 2001-11-06 Cohesion Technologies, Inc. Rapid gelling biocompatible polymer composition
US6916488B1 (en) 1999-11-05 2005-07-12 Biocure, Inc. Amphiphilic polymeric vesicles
US20020006886A1 (en) 1999-11-19 2002-01-17 Peter William Beerse Personal care articles comprising cationic polymer coacervate compositions
CA2402773C (en) 2000-03-13 2011-10-11 Biocure, Inc. Tissue bulking and coating compositions
US7056554B2 (en) 2000-08-02 2006-06-06 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Production of polyelectrolyte capsules by surface precipitation
US6488870B1 (en) 2000-11-27 2002-12-03 Xerox Corporation Encapsulation process
MXPA03007665A (es) 2001-02-26 2004-03-16 Univ Duke Polimeros dendriticos novedosos y sus usos biomedicos.
US6568398B2 (en) 2001-03-07 2003-05-27 Edgar C. Cohen Method for hemostasis
US6562361B2 (en) 2001-05-02 2003-05-13 3M Innovative Properties Company Pheromone immobilized in stable hydrogel microbeads
FR2824756B1 (fr) 2001-05-16 2005-07-08 Mainelab Microcapsules a base de proteines vegetales
WO2002100453A1 (en) 2001-06-07 2002-12-19 Surmodics, Inc. Crosslinkable macromers
US6559233B2 (en) 2001-07-13 2003-05-06 Rhodia Chimie Composition comprising a copolymer at least two charged blocks and type of opposite charge
US7204997B2 (en) 2002-01-29 2007-04-17 Supratek Pharma Inc. Responsive microgel and methods related thereto
JP2005526879A (ja) 2002-03-11 2005-09-08 ファースト ウォーター リミテッド 吸収性ハイドロゲル
JP4058283B2 (ja) 2002-03-22 2008-03-05 株式会社リコー 振動検出装置
US7060798B2 (en) 2002-05-13 2006-06-13 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education On Behalf Of Oregon State University Modified protein adhesives and lignocellulosic composites made from the adhesives
US6958848B2 (en) 2002-05-23 2005-10-25 E Ink Corporation Capsules, materials for use therein and electrophoretic media and displays containing such capsules
US6800663B2 (en) 2002-10-18 2004-10-05 Alkermes Controlled Therapeutics Inc. Ii, Crosslinked hydrogel copolymers
US8105652B2 (en) 2002-10-24 2012-01-31 Massachusetts Institute Of Technology Methods of making decomposable thin films of polyelectrolytes and uses thereof
CN1446590A (zh) 2003-01-21 2003-10-08 华东理工大学 新型聚肽/磷酸钙复合骨水泥
DE10334753A1 (de) 2003-07-30 2005-03-10 Constr Res & Tech Gmbh Selbstvernetzende hochmolekulare Polyurethan-Dispersion
CA2535513A1 (en) * 2003-08-11 2005-03-03 University Of Utah Research Foundation Crosslinking within coordination complexes
US7544770B2 (en) 2003-08-29 2009-06-09 Louisiana Tech Foundation, Inc. Multilayer films, coatings, and microcapsules comprising polypeptides
DE60327766D1 (de) 2003-09-25 2009-07-09 Rhodia Chimie Sa Mizellen mit einem Komplexkoazervatkern als fäulnishemmende Mittel
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
AU2004289287A1 (en) 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US7780873B2 (en) 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
WO2007024972A2 (en) 2005-08-22 2007-03-01 Quick-Med Technologies, Inc. Non-leaching absorbent wound dressing
US7854924B2 (en) 2004-03-30 2010-12-21 Relypsa, Inc. Methods and compositions for treatment of ion imbalances
KR100974733B1 (ko) 2004-04-28 2010-08-06 안지오디바이스 인터내셔널 게엠베하 가교된 생합성물질을 형성하기 위한 조성물 및 시스템, 및이와 관련된 제조 및 사용 방법
US8728526B2 (en) 2004-08-19 2014-05-20 The United States of America, Represented by Secretary of Department of Health and Human Services, NIH Coacervate microparticles useful for the sustained release administration of therapeutic agents
US20060039950A1 (en) 2004-08-23 2006-02-23 Zhengrong Zhou Multi-functional biocompatible coatings for intravascular devices
US20060116682A1 (en) 2004-11-18 2006-06-01 Longo Marc N Surgical implant and methods of making and using the same
US7795359B2 (en) 2005-03-04 2010-09-14 Novartis Ag Continuous process for production of polymeric materials
EP1888729A4 (en) 2005-06-01 2009-07-08 Rhodia KOAZERVATSYSTEME WITH ANTI-GROUNDING AND ANTI-DEPOSITION PROPERTIES ON HYDROPHILIC SURFACES
CA2925688C (en) 2005-09-09 2019-10-22 Farshid Guilak Tissue engineering methods and compositions
AU2007204872B2 (en) 2006-01-11 2013-04-04 Hyperbranch Medical Technology, Inc. Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices
US9198981B2 (en) 2006-02-01 2015-12-01 The University Of Kentucky Modulation of angiogenesis
WO2007097710A1 (en) 2006-02-27 2007-08-30 Agency For Science, Technology And Research Curable bone cement
AU2007283772B2 (en) 2006-08-04 2013-03-07 Kensey Nash Corporation Biomimetic compounds and synthetic methods therefor
DE102007015698B4 (de) 2007-03-27 2009-05-14 Innotere Gmbh Implantatmaterial auf Basis eines Polymersystems und dessen Verwendung sowie Applikationsset
JP2009084224A (ja) 2007-09-28 2009-04-23 Fujifilm Corp マイクロカプセル及びその製造方法
EP2222281B1 (en) 2007-12-20 2018-12-05 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
US8283384B2 (en) 2008-01-24 2012-10-09 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
CA2712843A1 (en) 2008-01-24 2009-07-30 University Of Utah Research Foundation Adhesive complex coacervates and methods of making and using thereof
CA2731072C (en) 2008-07-18 2016-11-08 Quick-Med Technologies, Inc. Polyelectrolyte complex for imparting antimicrobial properties to a substrate
WO2010021930A1 (en) 2008-08-16 2010-02-25 Synedgen, Inc. Prevention and treatment of mrsa infections with chitosan-derivatives
JP2009084292A (ja) 2008-11-14 2009-04-23 Cell-Medicine Inc 免疫アジュバント
US8618250B2 (en) 2009-07-17 2013-12-31 The Texas A&M University System Designer collagens and use thereof
DE102009033616A1 (de) 2009-07-17 2011-01-20 Karl Heinz Linnig Gmbh & Co. Kg Kühlvorrichtung, insbesondere Brennkraftmaschinenkühlvorrichtung, mit einer Sekundärantriebsmaschine
CA2806559C (en) 2009-09-02 2018-06-26 Synedgen Inc. Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds
CA2788998A1 (en) 2010-02-26 2011-09-01 University Of Utah Research Foundation Adhesive complex coacervates produced from electrostatically associated block copolymers and methods for making and using the same
US20110287067A1 (en) 2010-05-24 2011-11-24 University Of Utah Research Foundation Reinforced adhesive complex coacervates and methods of making and using thereof
AU2011325961A1 (en) * 2010-11-12 2013-03-28 University Of Utah Research Foundation Simple adhesive coacervates and methods of making and using thereof
CN103930133A (zh) 2011-11-13 2014-07-16 桑那瑞斯公司 原位可交联的聚合物组合物及其方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9814778B2 (en) 2014-03-06 2017-11-14 The University Of Toledo Ionically crosslinked polyelectrolytes as underwater adhesives as controlled release vehicles

Also Published As

Publication number Publication date
CN103179992A (zh) 2013-06-26
AU2011325961A1 (en) 2013-03-28
US9173971B2 (en) 2015-11-03
US9421300B2 (en) 2016-08-23
US20160074556A1 (en) 2016-03-17
US20180147316A1 (en) 2018-05-31
US20120177918A1 (en) 2012-07-12
JP2014502296A (ja) 2014-01-30
EP2637708A2 (en) 2013-09-18
WO2012065148A2 (en) 2012-05-18
WO2012065148A3 (en) 2012-07-05
US9999700B1 (en) 2018-06-19

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