CA2808900A1 - Fast-dissolve dosage forms of 5-ht2c agonists - Google Patents
Fast-dissolve dosage forms of 5-ht2c agonists Download PDFInfo
- Publication number
- CA2808900A1 CA2808900A1 CA2808900A CA2808900A CA2808900A1 CA 2808900 A1 CA2808900 A1 CA 2808900A1 CA 2808900 A CA2808900 A CA 2808900A CA 2808900 A CA2808900 A CA 2808900A CA 2808900 A1 CA2808900 A1 CA 2808900A1
- Authority
- CA
- Canada
- Prior art keywords
- salt
- weight
- tetrahydro
- chloro
- benzazepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US61/402,589 | 2010-09-01 | ||
| PCT/US2011/049953 WO2012030951A1 (en) | 2010-09-01 | 2011-08-31 | Fast-dissolve dosage forms of 5-ht2c agonists |
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| CA2808900A1 true CA2808900A1 (en) | 2012-03-08 |
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| US (1) | US20140148442A1 (enExample) |
| EP (1) | EP2611781A1 (enExample) |
| JP (1) | JP2013536858A (enExample) |
| KR (1) | KR20130138768A (enExample) |
| CN (1) | CN103189358A (enExample) |
| AU (1) | AU2011296027A1 (enExample) |
| CA (1) | CA2808900A1 (enExample) |
| IN (1) | IN2013DN02552A (enExample) |
| MX (1) | MX2013002430A (enExample) |
| SG (2) | SG188363A1 (enExample) |
| WO (1) | WO2012030951A1 (enExample) |
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| WO2012030938A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids |
| SG188361A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Non-hygroscopic salts of 5-ht2c agonists |
| JP6272695B2 (ja) | 2010-09-01 | 2018-01-31 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 体重管理のために有用な５−ｈｔ２ｃアゴニストの改変放出剤形 |
| CA2808890A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Administration of lorcaserin to individuals with renal impairment |
| JP2015534563A (ja) | 2012-10-09 | 2015-12-03 | アリーナ ファーマシューティカルズ， インコーポレイテッド | 体重管理の方法 |
| WO2014135545A1 (en) * | 2013-03-05 | 2014-09-12 | Sandoz Ag | Solid dispersion comprising amorphous lorcaserin hydrochloride |
| EP2999692A1 (en) * | 2013-05-20 | 2016-03-30 | LEK Pharmaceuticals d.d. | Novel synthetic processes to 8-chloro-3-benzo[d]azepine via friedel-crafts alkylation of olefin |
| EP2868656A1 (en) * | 2013-11-05 | 2015-05-06 | LEK Pharmaceuticals d.d. | Stabilized amorphous lorcaserin hydrochloride |
| CN104936947B (zh) * | 2013-12-27 | 2017-03-08 | 杭州普晒医药科技有限公司 | 氯卡色林盐及其晶体、其制备方法和用途 |
| WO2015161730A1 (zh) | 2014-04-21 | 2015-10-29 | 杭州普晒医药科技有限公司 | 一种氯卡色林共晶及其制备方法、药物组合物和用途 |
| CN103901151A (zh) * | 2014-04-23 | 2014-07-02 | 湖北朗昕生化药业有限公司 | 一种hplc法检测氯卡色林盐酸盐含量的方法 |
| WO2016069875A1 (en) | 2014-10-30 | 2016-05-06 | Arena Pharmaceuticals, Inc. | Compositions and methods for ceasing tobacco smoking |
| AU2017290107A1 (en) | 2016-06-29 | 2019-01-17 | CannScience Innovations Inc. | Decarboxylated cannabis resins, uses thereof and methods of making same |
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| FR2561916B1 (fr) | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
| US4642903A (en) | 1985-03-26 | 1987-02-17 | R. P. Scherer Corporation | Freeze-dried foam dosage form |
| US5073374A (en) | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
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| US5188825A (en) | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
| PT100602A (pt) * | 1991-06-21 | 1993-09-30 | Smithkline Beecham Plc | Uso de derivados de tetra-hidrobenzazepinas, derivados de tetra-hidrobenzazepinas,sua preparacao e composicoes farmaceuticas que os contem |
| US5464632C1 (en) | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
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-
2011
- 2011-08-31 JP JP2013527262A patent/JP2013536858A/ja active Pending
- 2011-08-31 WO PCT/US2011/049953 patent/WO2012030951A1/en not_active Ceased
- 2011-08-31 CA CA2808900A patent/CA2808900A1/en not_active Abandoned
- 2011-08-31 EP EP11755511.0A patent/EP2611781A1/en not_active Withdrawn
- 2011-08-31 US US13/820,123 patent/US20140148442A1/en not_active Abandoned
- 2011-08-31 IN IN2552DEN2013 patent/IN2013DN02552A/en unknown
- 2011-08-31 SG SG2013015607A patent/SG188363A1/en unknown
- 2011-08-31 CN CN201180052517XA patent/CN103189358A/zh active Pending
- 2011-08-31 KR KR1020137008322A patent/KR20130138768A/ko not_active Withdrawn
- 2011-08-31 MX MX2013002430A patent/MX2013002430A/es not_active Application Discontinuation
- 2011-08-31 SG SG10201506873WA patent/SG10201506873WA/en unknown
- 2011-08-31 AU AU2011296027A patent/AU2011296027A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN103189358A (zh) | 2013-07-03 |
| KR20130138768A (ko) | 2013-12-19 |
| SG10201506873WA (en) | 2015-10-29 |
| IN2013DN02552A (enExample) | 2015-08-07 |
| AU2011296027A1 (en) | 2013-04-04 |
| US20140148442A1 (en) | 2014-05-29 |
| SG188363A1 (en) | 2013-04-30 |
| WO2012030951A1 (en) | 2012-03-08 |
| MX2013002430A (es) | 2013-07-22 |
| JP2013536858A (ja) | 2013-09-26 |
| EP2611781A1 (en) | 2013-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20170831 |