CA2808900A1 - Fast-dissolve dosage forms of 5-ht2c agonists - Google Patents
Fast-dissolve dosage forms of 5-ht2c agonists Download PDFInfo
- Publication number
- CA2808900A1 CA2808900A1 CA2808900A CA2808900A CA2808900A1 CA 2808900 A1 CA2808900 A1 CA 2808900A1 CA 2808900 A CA2808900 A CA 2808900A CA 2808900 A CA2808900 A CA 2808900A CA 2808900 A1 CA2808900 A1 CA 2808900A1
- Authority
- CA
- Canada
- Prior art keywords
- salt
- weight
- tetrahydro
- chloro
- benzazepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| PCT/US2011/049953 WO2012030951A1 (en) | 2010-09-01 | 2011-08-31 | Fast-dissolve dosage forms of 5-ht2c agonists |
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| CA2808900A1 true CA2808900A1 (en) | 2012-03-08 |
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| JP (1) | JP2013536858A (enExample) |
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| CN (1) | CN103189358A (enExample) |
| AU (1) | AU2011296027A1 (enExample) |
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| IN (1) | IN2013DN02552A (enExample) |
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| WO (1) | WO2012030951A1 (enExample) |
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| KR20140091458A (ko) | 2010-09-01 | 2014-07-21 | 아레나 파마슈티칼스, 인크. | 신장 손상을 갖는 개체에 대한 로카세린의 투여 |
| CA2808909A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids |
| CN107669687A (zh) | 2010-09-01 | 2018-02-09 | 艾尼纳制药公司 | 用于体重控制的5‑ht2c激动剂的调节释放剂型 |
| CN103189360A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 5-ht2c激动剂的非吸湿性盐 |
| JP2015534563A (ja) | 2012-10-09 | 2015-12-03 | アリーナ ファーマシューティカルズ， インコーポレイテッド | 体重管理の方法 |
| WO2014135545A1 (en) * | 2013-03-05 | 2014-09-12 | Sandoz Ag | Solid dispersion comprising amorphous lorcaserin hydrochloride |
| EP2999692A1 (en) * | 2013-05-20 | 2016-03-30 | LEK Pharmaceuticals d.d. | Novel synthetic processes to 8-chloro-3-benzo[d]azepine via friedel-crafts alkylation of olefin |
| EP2868656A1 (en) * | 2013-11-05 | 2015-05-06 | LEK Pharmaceuticals d.d. | Stabilized amorphous lorcaserin hydrochloride |
| WO2015096119A1 (zh) * | 2013-12-27 | 2015-07-02 | 杭州普晒医药科技有限公司 | 氯卡色林盐及其晶体、其制备方法和用途 |
| CN105228986B (zh) | 2014-04-21 | 2017-11-07 | 杭州普晒医药科技有限公司 | 一种氯卡色林共晶及其制备方法、药物组合物和用途 |
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| TW201618787A (zh) | 2014-10-30 | 2016-06-01 | 艾尼納製藥公司 | 組合物及方法 |
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| US5073374A (en) | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
| US5112616A (en) | 1988-11-30 | 1992-05-12 | Schering Corporation | Fast dissolving buccal tablet |
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| US5223264A (en) | 1989-10-02 | 1993-06-29 | Cima Labs, Inc. | Pediatric effervescent dosage form |
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| US5188825A (en) | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
| CA2110575A1 (en) * | 1991-06-21 | 1993-01-07 | John Gerard Ward | Use of tetrahydrobenzazepine derivatives for the treatment of portal hypertension and migraine |
| US5464632C1 (en) | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
| DE69331839T2 (de) | 1992-01-29 | 2002-12-12 | Takeda Chemical Industries, Ltd. | Schnellösliche Tablette und ihre Herstellung |
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| US5595761A (en) | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
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| US5635210A (en) | 1994-02-03 | 1997-06-03 | The Board Of Regents Of The University Of Oklahoma | Method of making a rapidly dissolving tablet |
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-
2011
- 2011-08-31 SG SG10201506873WA patent/SG10201506873WA/en unknown
- 2011-08-31 EP EP11755511.0A patent/EP2611781A1/en not_active Withdrawn
- 2011-08-31 MX MX2013002430A patent/MX2013002430A/es not_active Application Discontinuation
- 2011-08-31 SG SG2013015607A patent/SG188363A1/en unknown
- 2011-08-31 IN IN2552DEN2013 patent/IN2013DN02552A/en unknown
- 2011-08-31 KR KR1020137008322A patent/KR20130138768A/ko not_active Withdrawn
- 2011-08-31 JP JP2013527262A patent/JP2013536858A/ja active Pending
- 2011-08-31 CN CN201180052517XA patent/CN103189358A/zh active Pending
- 2011-08-31 WO PCT/US2011/049953 patent/WO2012030951A1/en not_active Ceased
- 2011-08-31 AU AU2011296027A patent/AU2011296027A1/en not_active Abandoned
- 2011-08-31 CA CA2808900A patent/CA2808900A1/en not_active Abandoned
- 2011-08-31 US US13/820,123 patent/US20140148442A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013536858A (ja) | 2013-09-26 |
| EP2611781A1 (en) | 2013-07-10 |
| SG188363A1 (en) | 2013-04-30 |
| KR20130138768A (ko) | 2013-12-19 |
| US20140148442A1 (en) | 2014-05-29 |
| IN2013DN02552A (enExample) | 2015-08-07 |
| AU2011296027A1 (en) | 2013-04-04 |
| WO2012030951A1 (en) | 2012-03-08 |
| CN103189358A (zh) | 2013-07-03 |
| MX2013002430A (es) | 2013-07-22 |
| SG10201506873WA (en) | 2015-10-29 |
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Legal Events
| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20170831 |