CA2802635A1 - Peptides as active agents to stabilize biologic barriers - Google Patents

Peptides as active agents to stabilize biologic barriers Download PDF

Info

Publication number
CA2802635A1
CA2802635A1 CA2802635A CA2802635A CA2802635A1 CA 2802635 A1 CA2802635 A1 CA 2802635A1 CA 2802635 A CA2802635 A CA 2802635A CA 2802635 A CA2802635 A CA 2802635A CA 2802635 A1 CA2802635 A1 CA 2802635A1
Authority
CA
Canada
Prior art keywords
seq
peptide
xib
peptides
lps
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2802635A
Other languages
English (en)
French (fr)
Inventor
Peter Petzelbauer
Sonja Reingruber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XiberScience GmbH
Original Assignee
XiberScience GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by XiberScience GmbH filed Critical XiberScience GmbH
Publication of CA2802635A1 publication Critical patent/CA2802635A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2802635A 2010-06-18 2011-06-17 Peptides as active agents to stabilize biologic barriers Abandoned CA2802635A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT10102010 2010-06-18
ATA1010/2010(4BA1010 2010-06-18
PCT/EP2011/060105 WO2011157819A2 (en) 2010-06-18 2011-06-17 Peptides as active agents to stabilize biological barriers

Publications (1)

Publication Number Publication Date
CA2802635A1 true CA2802635A1 (en) 2011-12-22

Family

ID=44628513

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2802635A Abandoned CA2802635A1 (en) 2010-06-18 2011-06-17 Peptides as active agents to stabilize biologic barriers

Country Status (8)

Country Link
US (1) US9012403B2 (cg-RX-API-DMAC7.html)
EP (1) EP2582720B1 (cg-RX-API-DMAC7.html)
JP (1) JP5709985B2 (cg-RX-API-DMAC7.html)
CN (1) CN103038253A (cg-RX-API-DMAC7.html)
CA (1) CA2802635A1 (cg-RX-API-DMAC7.html)
ES (1) ES2486321T3 (cg-RX-API-DMAC7.html)
RU (1) RU2012157399A (cg-RX-API-DMAC7.html)
WO (1) WO2011157819A2 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103068400A (zh) 2010-06-25 2013-04-24 阿斯顿大学 具有脂类动员性质的糖蛋白及其治疗用途
WO2015022326A1 (en) 2013-08-12 2015-02-19 Xiber Science Gmbh Peptides as active agents for treating primary graft dysfunction
NL2015130B1 (en) * 2015-07-09 2017-02-01 Mimetas B V Barrier function measurements.
EP3436070A4 (en) * 2016-03-29 2019-11-27 University of Southern California AGAINST CANCER, CHIMERIC ANTIGEN RECEPTORS
MX2021001877A (es) * 2018-08-17 2021-07-15 Univ Pennsylvania Composiciones y métodos para el tratamiento de lesión pulmonar aguda.
US20220062391A1 (en) * 2019-01-16 2022-03-03 University Of Rochester Enhancing epithelial or endothelial barrier function
EP4093423A1 (en) 2020-01-22 2022-11-30 UCL Business Ltd Peptide inhibitors of guanine nucleotide exchange factor-h1

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
EP0052322B1 (de) 1980-11-10 1985-03-27 Gersonde, Klaus, Prof. Dr. Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
JPS58118008A (ja) 1982-01-06 1983-07-13 Nec Corp デ−タ処理装置
EP0088046B1 (de) 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
DE3218121A1 (de) 1982-05-14 1983-11-17 Leskovar, Peter, Dr.-Ing., 8000 München Arzneimittel zur tumorbehandlung
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
EP0102324A3 (de) 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
DE3483949D1 (de) 1983-09-26 1991-02-21 Udo Dr Med Ehrenfeld Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
EP0143949B1 (en) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Pharmaceutical composition containing urokinase
US5792608A (en) 1991-12-12 1998-08-11 Gilead Sciences, Inc. Nuclease stable and binding competent oligomers and methods for their use
US5525711A (en) 1994-05-18 1996-06-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pteridine nucleotide analogs as fluorescent DNA probes
US6372250B1 (en) * 2000-04-25 2002-04-16 The Regents Of The University Of California Non-invasive gene targeting to the brain
US20040053250A1 (en) * 2001-03-05 2004-03-18 Tang Y. Tom Novel arginine-rich protein-like nucleic acids and polypeptides
EP1519957B1 (en) * 2002-07-03 2009-03-04 Fondazione Centro San Raffaele Del Monte Tabor Use of hmgb1 in the treatment of tissue damage and/or to promote tissue repair
AU2007223888A1 (en) 2006-03-06 2007-09-13 Amunix, Inc. Genetic packages and uses thereof
EA021222B8 (ru) 2007-06-21 2015-11-30 ИксЭль-ПРОТЕИН ГМБХ Биологически активные белки, имеющие повышенную стабильность in vivo и/или in vitro

Also Published As

Publication number Publication date
ES2486321T3 (es) 2014-08-18
EP2582720A2 (en) 2013-04-24
WO2011157819A3 (en) 2012-02-23
JP2013529916A (ja) 2013-07-25
EP2582720B1 (en) 2014-05-21
US9012403B2 (en) 2015-04-21
CN103038253A (zh) 2013-04-10
JP5709985B2 (ja) 2015-04-30
RU2012157399A (ru) 2014-07-27
WO2011157819A2 (en) 2011-12-22
US20130143791A1 (en) 2013-06-06

Similar Documents

Publication Publication Date Title
EP2582720B1 (en) Peptides as active agents to stabilize biological barriers
US7718610B2 (en) Retrocyclins: antiviral and antimicrobial peptides
JP2022545554A (ja) Q-erペプチド
EP4013440A1 (en) Therapeutic peptides
US11117930B2 (en) Peptide inhibitors of transcription factor aggregation
US11787850B2 (en) Peptidic TGF-beta antagonists
EP4135738A2 (en) Method of treating coronavirus infections
WO2015022326A1 (en) Peptides as active agents for treating primary graft dysfunction
US9683025B2 (en) Methods and compositions for treating cancer and inflammatory diseases
WO2014047194A1 (en) Antagonist for (pro)renin receptor for the treatment of hypertension and diabetes
US10335449B2 (en) Rho associated kinase (ROCK) inhibitors and their use in treating disease
US20240197828A1 (en) Chimeric molecule to treat sepsis and other inflammatory conditions
CN103214555B (zh) 介导应激反应的肽抑制剂
HK1184167A (en) Peptides as active agents to stabilize biological barriers
US9573976B2 (en) Antagonist for (pro)renin receptor for the treatment of hypertension and diabetes
WO2016042411A1 (en) Ncx1 peptides and uses thereof
KR20250138134A (ko) 표적 단백질 분해자 및 세포 투과 펩타이드를 포함하는 융합 분자 및 이의 용도
US20230374087A1 (en) Method to improve protein quality control
EP2060581A1 (en) Scaffold proteins for recombinant peptide aptamers
WO2013023166A2 (en) Hapivirins and diprovirins
HK1232443A1 (en) Synthesis of beta-arrestin effectors
HK1258994A1 (zh) 用於疾病治疗的方法
JP2015126722A (ja) 新規ユビキチンリガーゼ及びその利用方法

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20170619