CA2786545A1 - Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof - Google Patents

Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof Download PDF

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Publication number
CA2786545A1
CA2786545A1 CA2786545A CA2786545A CA2786545A1 CA 2786545 A1 CA2786545 A1 CA 2786545A1 CA 2786545 A CA2786545 A CA 2786545A CA 2786545 A CA2786545 A CA 2786545A CA 2786545 A1 CA2786545 A1 CA 2786545A1
Authority
CA
Canada
Prior art keywords
bonj
snp
gene
predisposition
biomarker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2786545A
Other languages
English (en)
French (fr)
Inventor
Joseph Katz
Taimour Y. Langaee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida Research Foundation Inc
Original Assignee
University of Florida Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Florida Research Foundation Inc filed Critical University of Florida Research Foundation Inc
Publication of CA2786545A1 publication Critical patent/CA2786545A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2786545A 2010-01-06 2010-12-13 Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof Abandoned CA2786545A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29273010P 2010-01-06 2010-01-06
US61/292,730 2010-01-06
PCT/US2010/060139 WO2011084387A2 (en) 2010-01-06 2010-12-13 Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof

Publications (1)

Publication Number Publication Date
CA2786545A1 true CA2786545A1 (en) 2011-07-14

Family

ID=44306025

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2786545A Abandoned CA2786545A1 (en) 2010-01-06 2010-12-13 Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof

Country Status (9)

Country Link
US (1) US20130035314A1 (https=)
EP (1) EP2521793A4 (https=)
CN (1) CN102812132A (https=)
AU (1) AU2010340161A1 (https=)
BR (1) BR112012016744A2 (https=)
CA (1) CA2786545A1 (https=)
IN (1) IN2012DN06571A (https=)
RU (1) RU2012133434A (https=)
WO (1) WO2011084387A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010005939A1 (en) * 2008-07-07 2010-01-14 University Of Florida Research Foundation, Inc. Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof
WO2015083163A1 (en) * 2013-12-04 2015-06-11 Micromedic Technologies Ltd. Methods and kits for identifying susceptability to antiresorptive-agent-induced osteonecrosis of the jaw
CN111518882B (zh) * 2019-02-03 2022-06-28 陈卫衡 通过分子标志物辨识激素性股骨头坏死的中医证型的系统
CN112410413A (zh) * 2020-09-24 2021-02-26 吉林大学 Onfh易感相关vdr、mmp2、mmp3、mmp9基因snp的检测物质及应用
ES2994026A1 (es) * 2023-07-11 2025-01-16 Fundacion Instituto De Investig Sanitaria De Santiago De Compostela Metodo in vitro para identificar si un sujeto tratado con agentes modificadores de los huesos puede desarrollar osteonecrosis de los maxilares

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003062465A1 (es) * 2002-01-25 2003-07-31 Universidad De Barcelona Compuestos para el diagnóstico de la predisposición a la osteoporosis
WO2010005939A1 (en) * 2008-07-07 2010-01-14 University Of Florida Research Foundation, Inc. Methods and kits for detecting risk factors for development of jaw osteonecrosis and methods of treatment thereof

Also Published As

Publication number Publication date
RU2012133434A (ru) 2014-02-27
EP2521793A4 (en) 2013-07-03
AU2010340161A1 (en) 2012-07-26
US20130035314A1 (en) 2013-02-07
IN2012DN06571A (https=) 2015-10-23
EP2521793A2 (en) 2012-11-14
BR112012016744A2 (pt) 2017-06-13
WO2011084387A2 (en) 2011-07-14
WO2011084387A3 (en) 2011-10-27
CN102812132A (zh) 2012-12-05

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130904

FZDE Discontinued

Effective date: 20151215