CA2776522C - Development of a preventive vaccine for filovirus infection in primates - Google Patents
Development of a preventive vaccine for filovirus infection in primates Download PDFInfo
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- CA2776522C CA2776522C CA2776522A CA2776522A CA2776522C CA 2776522 C CA2776522 C CA 2776522C CA 2776522 A CA2776522 A CA 2776522A CA 2776522 A CA2776522 A CA 2776522A CA 2776522 C CA2776522 C CA 2776522C
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- ebola
- glycoprotein
- marburg
- pvr1012
- sequence
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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- C12N2760/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14111—Ebolavirus, e.g. Zaire ebolavirus
- C12N2760/14134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/14011—Filoviridae
- C12N2760/14211—Marburgvirus, e.g. lake Victoria marburgvirus
- C12N2760/14222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Veterinary Medicine (AREA)
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- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32647601P | 2001-10-01 | 2001-10-01 | |
| US60/326,476 | 2001-10-01 | ||
| CA2462455A CA2462455C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2462455A Division CA2462455C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2776522A1 CA2776522A1 (en) | 2003-04-10 |
| CA2776522C true CA2776522C (en) | 2015-02-17 |
Family
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Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2776522A Expired - Lifetime CA2776522C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
| CA 2776391 Expired - Lifetime CA2776391C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
| CA2776272A Expired - Lifetime CA2776272C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
| CA2462455A Expired - Lifetime CA2462455C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2776391 Expired - Lifetime CA2776391C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
| CA2776272A Expired - Lifetime CA2776272C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
| CA2462455A Expired - Lifetime CA2462455C (en) | 2001-10-01 | 2002-09-24 | Development of a preventive vaccine for filovirus infection in primates |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US7635688B2 (enExample) |
| EP (1) | EP1504112A4 (enExample) |
| JP (2) | JP2005508916A (enExample) |
| AT (1) | ATE396739T1 (enExample) |
| AU (1) | AU2002327049B2 (enExample) |
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| DE (1) | DE60226911D1 (enExample) |
| ES (1) | ES2307093T3 (enExample) |
| WO (1) | WO2003028632A2 (enExample) |
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| EP1654370B1 (en) * | 2003-08-01 | 2018-05-30 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Accelerated ebola vaccination |
| EP1675613B1 (en) * | 2003-09-15 | 2012-05-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Hiv vaccines based on env of multiple clades of hiv |
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| EP1737885A2 (en) * | 2004-04-12 | 2007-01-03 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Method of using adenoviral vectors to induce an immune response |
| AU2005274948B2 (en) * | 2004-07-16 | 2011-09-22 | Genvec, Inc. | Vaccines against aids comprising CMV/R-nucleic acid constructs |
| CA2581840C (en) | 2004-09-27 | 2014-08-05 | Crucell Holland B.V. | Optimized vaccines to provide protection against ebola and other viruses |
| DK1869171T4 (en) | 2005-04-11 | 2016-01-18 | Crucell Holland Bv | Virus cleaning using ultrafiltration |
| CA2604909A1 (en) | 2005-04-15 | 2006-10-26 | The Government Of The United States Of America, As Represented By The Se Cretary, Department Of Health And Human Services | Methods and compositions for producing an enhanced immune response to a human papillomavirus immunogen |
| US20070185025A1 (en) * | 2005-09-11 | 2007-08-09 | The Trustees Of Columbia University In The City Of New York | Filoviral immunosuppressive peptides and uses thereof |
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| CA2642644A1 (en) * | 2006-02-16 | 2007-09-07 | The Government Of The United States Of America, As Represented By The Se Cretary, Department Of Health And Human Services | Antiviral agents and vaccines against influenza |
| EP2152889B1 (en) | 2007-05-29 | 2017-03-15 | Nature Technology Corporation | Vectors and methods for genetic immunization |
| WO2009092038A1 (en) * | 2008-01-16 | 2009-07-23 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Influenza dna vaccination and methods of use thereof |
| AU2009259456A1 (en) | 2008-06-20 | 2009-12-23 | Basf Se | Agrochemical formulations comprising a pesticide, an organic UV-photoprotective filter and coated metal-oxide nanoparticles |
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| US20120219584A1 (en) | 2009-10-05 | 2012-08-30 | The United States Of America As Represented By The Secretary, Department Of Health | Protection against pandemic and seasonal strains of influenza |
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| WO2011130627A2 (en) | 2010-04-16 | 2011-10-20 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Chimpanzee adenoviral vector-based filovirus vaccines |
| EP3593802A3 (en) | 2010-05-26 | 2020-03-25 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
| CN103370411B (zh) * | 2010-12-14 | 2016-05-04 | 美国卫生和人类服务部 | 腺病毒血清型26和血清型35线状病毒疫苗 |
| WO2012170814A1 (en) * | 2011-06-08 | 2012-12-13 | The Ohio State University | Norovirus immunogens and related materials and methods |
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| CA2849822C (en) | 2011-09-23 | 2021-05-11 | Gary J. Nabel, M.D. | Novel influenza hemagglutinin protein-based vaccines |
| EA030839B1 (ru) | 2011-10-28 | 2018-10-31 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециклинга желчных кислот при лечении холестатических заболеваний печени у детей |
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| KR102877352B1 (ko) * | 2012-04-12 | 2025-10-29 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 필로바이러스 공통 항원, 이로부터 제조된 핵산 구조체 및 백신, 및 이를 사용하는 방법 |
| CN105792842B (zh) | 2013-10-11 | 2020-06-02 | 美利坚合众国, 由健康及人类服务部部长代表 | 埃巴病毒疫苗 |
| TWI516602B (zh) | 2013-10-29 | 2016-01-11 | 臺北醫學大學 | 高通量篩選高表現細胞之方法及由其篩選之細胞 |
| CN114014937A (zh) | 2014-05-27 | 2022-02-08 | 美利坚合众国, 由健康及人类服务部部长代表 | 稳定化的流感血凝素茎区三聚体及其用途 |
| SG10201901735XA (en) * | 2014-09-03 | 2019-03-28 | Bavarian Nordic As | Recombinant modified vaccinia virus ankara (mva) filovirus vaccine |
| SG11201705264WA (en) | 2014-12-31 | 2017-07-28 | The Usa As Represented By The Secretary Detp Of Health And Human Services | Novel multivalent nanoparticle-based vaccines |
| CA2974114A1 (en) * | 2015-01-28 | 2016-08-04 | Integrated Biotherapeutics, Inc. | Equine immunoglobulin compositions and uses for treating filovirus-mediated diseases |
| TN2018000187A1 (en) | 2015-12-04 | 2019-10-04 | Dana Farber Cancer Inst Inc | Vaccination with mica/b alpha 3 domain for the treatment of cancer |
| US11459619B2 (en) | 2016-02-08 | 2022-10-04 | The Johns Hopkins University | Handheld nucleic acid-based assay for rapid identification |
| IL265121B2 (en) | 2016-09-02 | 2023-11-01 | Us Health | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
| WO2019028266A1 (en) | 2017-08-02 | 2019-02-07 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | HEPATITIS B NANOPARTICLE VACCINE FOR INFLUENZA VIRUS |
| CA3100070A1 (en) * | 2018-05-18 | 2019-11-21 | Universite Laval | Vectors for dna vaccination |
| CN113423718A (zh) | 2019-02-08 | 2021-09-21 | 美国政府(由卫生和人类服务部的部长所代表) | 基于纳米颗粒的流感病毒疫苗及其用途 |
| WO2024138204A1 (en) | 2022-12-22 | 2024-06-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Stabilized pfs48/45 proteins and uses thereof |
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| US6171596B1 (en) | 1993-12-10 | 2001-01-09 | The United States Of America As Represented By The Department Of Health And Human Services | Oligomeric HIV-1 envelope glycoproteins |
| US6027881A (en) | 1996-05-08 | 2000-02-22 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Mutant Aequorea victoria fluorescent proteins having increased cellular fluorescence |
| US6200959B1 (en) | 1996-12-04 | 2001-03-13 | Powerject Vaccines Inc. | Genetic induction of anti-viral immune response and genetic vaccine for filovirus |
| WO1999032147A1 (en) * | 1997-12-23 | 1999-07-01 | The Regents Of The University Of Michigan | Immunization for ebola virus infection |
| WO2001016183A1 (en) | 1999-08-30 | 2001-03-08 | U.S. Army Medical Research Institute Of Infectious Diseases | Monoclonal antibodies and vaccines against epitopes on the ebola virus glycoprotein |
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2002
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- 2002-09-24 WO PCT/US2002/030251 patent/WO2003028632A2/en not_active Ceased
- 2002-09-24 CA CA 2776391 patent/CA2776391C/en not_active Expired - Lifetime
- 2002-09-24 CA CA2776272A patent/CA2776272C/en not_active Expired - Lifetime
- 2002-09-24 JP JP2003531968A patent/JP2005508916A/ja active Pending
- 2002-09-24 US US10/491,121 patent/US7635688B2/en not_active Expired - Lifetime
- 2002-09-24 AU AU2002327049A patent/AU2002327049B2/en not_active Expired
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- 2002-09-24 ES ES05013732T patent/ES2307093T3/es not_active Expired - Lifetime
- 2002-09-24 AT AT05013732T patent/ATE396739T1/de not_active IP Right Cessation
- 2002-09-24 CA CA2462455A patent/CA2462455C/en not_active Expired - Lifetime
- 2002-09-24 EP EP02761814A patent/EP1504112A4/en not_active Ceased
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- 2009-11-04 US US12/612,625 patent/US8124592B2/en not_active Expired - Fee Related
- 2009-11-04 US US12/612,579 patent/US8106026B2/en not_active Expired - Fee Related
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| CA2776391A1 (en) | 2003-04-10 |
| US7635688B2 (en) | 2009-12-22 |
| US20060148087A1 (en) | 2006-07-06 |
| CA2776522A1 (en) | 2003-04-10 |
| CA2776272A1 (en) | 2003-04-10 |
| US20100297171A1 (en) | 2010-11-25 |
| WO2003028632A2 (en) | 2003-04-10 |
| US20040259825A1 (en) | 2004-12-23 |
| JP2006081549A (ja) | 2006-03-30 |
| JP2005508916A (ja) | 2005-04-07 |
| ATE396739T1 (de) | 2008-06-15 |
| AU2002327049B2 (en) | 2008-04-03 |
| CA2462455C (en) | 2012-07-17 |
| WO2003028632A3 (en) | 2004-12-02 |
| CA2776391C (en) | 2015-03-31 |
| US20100303857A1 (en) | 2010-12-02 |
| EP1504112A2 (en) | 2005-02-09 |
| DE60226911D1 (de) | 2008-07-10 |
| US8124592B2 (en) | 2012-02-28 |
| US8106027B2 (en) | 2012-01-31 |
| US20100298414A1 (en) | 2010-11-25 |
| US8106026B2 (en) | 2012-01-31 |
| CA2462455A1 (en) | 2003-04-10 |
| CA2776272C (en) | 2016-05-17 |
| ES2307093T3 (es) | 2008-11-16 |
| JP4198148B2 (ja) | 2008-12-17 |
| US7094598B2 (en) | 2006-08-22 |
| EP1504112A4 (en) | 2006-02-08 |
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