CA2765876A1 - Compositions et methodes pour traiter la sclerose laterale amyotrophique (als) - Google Patents

Compositions et methodes pour traiter la sclerose laterale amyotrophique (als) Download PDF

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Publication number
CA2765876A1
CA2765876A1 CA2765876A CA2765876A CA2765876A1 CA 2765876 A1 CA2765876 A1 CA 2765876A1 CA 2765876 A CA2765876 A CA 2765876A CA 2765876 A CA2765876 A CA 2765876A CA 2765876 A1 CA2765876 A1 CA 2765876A1
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CA
Canada
Prior art keywords
subjects
dose
dexpramipexole
administering
als
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2765876A
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English (en)
Inventor
Valentin Gribkoff
Michael E. Bozik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Knopp Neurosciences Inc
Original Assignee
Knopp Neurosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43356795&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2765876(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Knopp Neurosciences Inc filed Critical Knopp Neurosciences Inc
Publication of CA2765876A1 publication Critical patent/CA2765876A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
CA2765876A 2009-06-19 2010-06-21 Compositions et methodes pour traiter la sclerose laterale amyotrophique (als) Abandoned CA2765876A1 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US21865909P 2009-06-19 2009-06-19
US61/218,659 2009-06-19
US26794509P 2009-12-09 2009-12-09
US61/267,945 2009-12-09
US31711810P 2010-03-24 2010-03-24
US61/317,118 2010-03-24
US35643910P 2010-06-18 2010-06-18
US61/356,439 2010-06-18
PCT/US2010/039379 WO2010148409A1 (fr) 2009-06-19 2010-06-21 Compositions et méthodes pour traiter la sclérose latérale amyotrophique (als)

Publications (1)

Publication Number Publication Date
CA2765876A1 true CA2765876A1 (fr) 2010-12-23

Family

ID=43356795

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2765876A Abandoned CA2765876A1 (fr) 2009-06-19 2010-06-21 Compositions et methodes pour traiter la sclerose laterale amyotrophique (als)

Country Status (12)

Country Link
US (2) US20110009460A1 (fr)
EP (1) EP2442655A4 (fr)
JP (1) JP2012530723A (fr)
CN (1) CN102802418A (fr)
AU (1) AU2010262970A1 (fr)
BR (1) BRPI1010084A2 (fr)
CA (1) CA2765876A1 (fr)
CL (1) CL2011003191A1 (fr)
CO (1) CO6480953A2 (fr)
MX (1) MX2011013577A (fr)
RU (1) RU2012101792A (fr)
WO (1) WO2010148409A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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US8518926B2 (en) 2006-04-10 2013-08-27 Knopp Neurosciences, Inc. Compositions and methods of using (R)-pramipexole
PL2026803T3 (pl) 2006-05-16 2012-05-31 Knopp Neurosciences Inc Kompozycje R(+) i S(-) pramipeksolu i sposoby ich zastosowania
US8524695B2 (en) 2006-12-14 2013-09-03 Knopp Neurosciences, Inc. Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
RU2454409C2 (ru) 2007-03-14 2012-06-27 Нопп Ньюросайенсиз, Инк. Синтез хирально очищенных замещенных бензотиазолдиаминов
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WO2013096870A1 (fr) * 2011-12-22 2013-06-27 Knopp Neurosciences Inc Compositions et procédés pour traiter la sclérose latérale amyotrophique
US9512096B2 (en) 2011-12-22 2016-12-06 Knopp Biosciences, LLP Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds
WO2014134569A1 (fr) * 2013-02-28 2014-09-04 Knopp Biosciences Llc Compositions et procédés de traitement de la sclérose latérale amyotrophique chez les patients répondant au traitement
US9662313B2 (en) 2013-02-28 2017-05-30 Knopp Biosciences Llc Compositions and methods for treating amyotrophic lateral sclerosis in responders
US9468630B2 (en) 2013-07-12 2016-10-18 Knopp Biosciences Llc Compositions and methods for treating conditions related to increased eosinophils
SI3019167T1 (sl) 2013-07-12 2021-04-30 Knopp Biosciences Llc Zdravljenje povišanih ravni eozinofilcev in / ali bazofilcev
US9763918B2 (en) 2013-08-13 2017-09-19 Knopp Biosciences Llc Compositions and methods for treating chronic urticaria
WO2015023786A1 (fr) 2013-08-13 2015-02-19 Knopp Biosciences Llc Compositions et méthodes de traitement de troubles des cellules plasmatiques et de troubles prolymphocytaires à cellules b
AU2014352920A1 (en) * 2013-11-22 2016-06-23 Genzyme Corporation Novel methods for treating neurodegenerative diseases
US20170248579A1 (en) * 2014-09-10 2017-08-31 The Uab Research Foundation Amyotrophic lateral sclerosis (als) biomarkers and uses thereof
WO2016207924A1 (fr) * 2015-06-25 2016-12-29 Chiarugi Alberto Dexpramipexole pour le traitement de la douleur
WO2017103224A1 (fr) * 2015-12-16 2017-06-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) Méthode de traitement de la sclérose latérale amyotrophique

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Also Published As

Publication number Publication date
US20130245081A1 (en) 2013-09-19
MX2011013577A (es) 2012-04-10
RU2012101792A (ru) 2013-07-27
AU2010262970A1 (en) 2012-01-12
US20110009460A1 (en) 2011-01-13
CN102802418A (zh) 2012-11-28
WO2010148409A1 (fr) 2010-12-23
BRPI1010084A2 (pt) 2015-08-25
CO6480953A2 (es) 2012-07-16
EP2442655A1 (fr) 2012-04-25
EP2442655A4 (fr) 2013-04-03
CL2011003191A1 (es) 2012-07-20
JP2012530723A (ja) 2012-12-06

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