CA2757828C - Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection - Google Patents
Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection Download PDFInfo
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- CA2757828C CA2757828C CA2757828A CA2757828A CA2757828C CA 2757828 C CA2757828 C CA 2757828C CA 2757828 A CA2757828 A CA 2757828A CA 2757828 A CA2757828 A CA 2757828A CA 2757828 C CA2757828 C CA 2757828C
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- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
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- A—HUMAN NECESSITIES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
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- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21198909P | 2009-04-06 | 2009-04-06 | |
| US61/211,989 | 2009-04-06 | ||
| US21660809P | 2009-05-19 | 2009-05-19 | |
| US61/216,608 | 2009-05-19 | ||
| PCT/CA2010/000516 WO2010115278A1 (en) | 2009-04-06 | 2010-04-06 | Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection |
Publications (2)
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| CA2757828A Active CA2757828C (en) | 2009-04-06 | 2010-04-06 | Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection |
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| CL2014001126A1 (es) * | 2014-04-29 | 2014-08-29 | Univ Chile | Composición farmacéutica útil como vacuna contra bacterias escherichia coli productoras de shigatoxinas (stec), que comprende al menos un antígeno o una proteína de membrana externa inmunogénica o proteína inmunogénica asociada y conservada en cepas stec. |
| KR20220007619A (ko) * | 2019-05-01 | 2022-01-18 | 이네이트 바이올로직스 엘엘씨 | 면역조절 조성물 및 방법 |
| EP4054655A4 (en) * | 2019-11-08 | 2024-02-28 | Ionis Pharmaceuticals, Inc. | COMPOUNDS AND METHODS FOR REDUCING SPDEF EXPRESSION |
| US20210369836A1 (en) * | 2020-05-26 | 2021-12-02 | Synlogic Operating Company, Inc. | Surface display of proteins on recombinant bacteria and uses thereof |
| WO2024064200A2 (en) * | 2022-09-20 | 2024-03-28 | The Texas A&M University System | Darpin-containing compositions and methods thereof |
| AR132724A1 (es) | 2024-05-17 | 2025-07-23 | Instituto Nac De Tecnologia Agropecuaria Inta | Construcción de adn que codifica una proteína de fusión con al menos dos antígenos de escherichia coli enterohemorrágica, vectores, proteína de fusión, métodos de inmunización y vacunas |
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| US5055400A (en) | 1986-11-26 | 1991-10-08 | University Of Guelph | Leukotoxin gene of pasteurella haemolytica |
| US4957739A (en) | 1987-08-13 | 1990-09-18 | Board Of Regents, The University Of Texas System | Pharmaceutical compositions of a 105 kD P. Haemolytica derived antigen useful for treatment of Shipping Fever |
| CA2014033C (en) | 1989-04-07 | 1993-02-09 | Stephen D. Acres | Compositions and treatments for pneumonia in animals |
| ES2108693T3 (es) * | 1990-04-05 | 1998-01-01 | Univ Saskatchewan | Compuestos y tratamientos para la neumonia en animales. |
| US5273889A (en) | 1990-08-22 | 1993-12-28 | University Of Saskatchewan | Gamma-iterferon-leukotoxin gene fusions and uses thereof |
| US5238823A (en) | 1990-08-22 | 1993-08-24 | Veterinary Infectious Disease Organization | Interleukin-2-leukotoxin gene fusions and uses thereof |
| US5594107A (en) * | 1990-08-22 | 1997-01-14 | University Of Saskatchewan | Chimeric protein comprising an RTX-family cytotoxin and interferon-2 or interferon |
| AU2699192A (en) | 1991-10-16 | 1993-05-21 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
| US5723129A (en) | 1991-10-16 | 1998-03-03 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
| US5422110A (en) | 1991-10-16 | 1995-06-06 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
| US6797272B1 (en) | 1991-10-16 | 2004-09-28 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
| US5837268A (en) | 1991-10-16 | 1998-11-17 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
| ES2389625T3 (es) | 1996-04-23 | 2012-10-29 | The University Of British Columbia | Vacuna que comprende la proteína EspA asociada a Escherichia coli patógena |
| EP1029054B1 (en) | 1997-11-12 | 2009-08-05 | The University Of British Columbia | Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene |
| EP1098661A2 (en) * | 1998-06-04 | 2001-05-16 | Metamorphix, Inc. | Gnrh vaccines for suppressing reproductive behavior in animals |
| US6365723B1 (en) | 1998-12-04 | 2002-04-02 | Wisconsin Alumni Research Foundation | Sequences of E. coli O157 |
| MXPA03006042A (es) * | 2001-01-04 | 2005-02-14 | Univ British Columbia | Vacuna de escherichia colienterohemorragica. |
| AU2002347314A1 (en) * | 2002-11-29 | 2004-06-23 | Imperial College Innovations Limited | Vaccine against enteropathogenic and enterohaemorragic escherichia coli |
| WO2007101337A1 (en) * | 2006-03-06 | 2007-09-13 | Bioniche Life Sciences Inc. | Methods and compositions comprising bacterial type hi secreted proteins for mucosal immunization of animals |
| EP2420246A1 (en) * | 2006-04-20 | 2012-02-22 | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. | Methods and compositions based on shiga toxin type 1 protein |
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| BRPI1014505A2 (pt) | 2016-04-05 |
| EP2417165A4 (en) | 2013-02-13 |
| AU2010234193A1 (en) | 2011-11-03 |
| US8734811B2 (en) | 2014-05-27 |
| JP2016029049A (ja) | 2016-03-03 |
| EP2417165A1 (en) | 2012-02-15 |
| BRPI1014505A8 (pt) | 2017-07-11 |
| WO2010115278A8 (en) | 2010-12-02 |
| CA2757828A1 (en) | 2010-10-14 |
| BRPI1014505B1 (pt) | 2020-02-04 |
| EP2417165B1 (en) | 2016-05-25 |
| US20120087939A1 (en) | 2012-04-12 |
| AU2010234193B2 (en) | 2015-08-20 |
| WO2010115278A1 (en) | 2010-10-14 |
| JP2012522522A (ja) | 2012-09-27 |
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