BRPI1014505A2 - métodos e composições para tratar e previnir infecção por escherichia coli produtora de toxina shiga. - Google Patents
métodos e composições para tratar e previnir infecção por escherichia coli produtora de toxina shiga.Info
- Publication number
- BRPI1014505A2 BRPI1014505A2 BRPI1014505A BRPI1014505A BRPI1014505A2 BR PI1014505 A2 BRPI1014505 A2 BR PI1014505A2 BR PI1014505 A BRPI1014505 A BR PI1014505A BR PI1014505 A BRPI1014505 A BR PI1014505A BR PI1014505 A2 BRPI1014505 A2 BR PI1014505A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- treating
- methods
- escherichia coli
- shiga toxin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1228—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K16/1232—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia from Escherichia (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21198909P | 2009-04-06 | 2009-04-06 | |
US21660809P | 2009-05-19 | 2009-05-19 | |
PCT/CA2010/000516 WO2010115278A1 (en) | 2009-04-06 | 2010-04-06 | Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI1014505A2 true BRPI1014505A2 (pt) | 2016-04-05 |
BRPI1014505A8 BRPI1014505A8 (pt) | 2017-07-11 |
BRPI1014505B1 BRPI1014505B1 (pt) | 2020-02-04 |
Family
ID=42935602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1014505A BRPI1014505B1 (pt) | 2009-04-06 | 2010-04-06 | Proteína de fusão de múltiplos epítopos, método para produzir uma composição, polinucleotídeo, vetor recombinante, célula hospedeira, método para produzir umaproteína de fusão de múltiplos epítopos, kit de teste imunodiagnóstico, composição, e, uso de uma proteína de fusão de múltiplos epítopos |
Country Status (7)
Country | Link |
---|---|
US (1) | US8734811B2 (pt) |
EP (1) | EP2417165B1 (pt) |
JP (2) | JP2012522522A (pt) |
AU (1) | AU2010234193B2 (pt) |
BR (1) | BRPI1014505B1 (pt) |
CA (1) | CA2757828C (pt) |
WO (1) | WO2010115278A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CL2014001126A1 (es) * | 2014-04-29 | 2014-08-29 | Univ Chile | Composición farmacéutica útil como vacuna contra bacterias escherichia coli productoras de shigatoxinas (stec), que comprende al menos un antígeno o una proteína de membrana externa inmunogénica o proteína inmunogénica asociada y conservada en cepas stec. |
US20210369836A1 (en) * | 2020-05-26 | 2021-12-02 | Synlogic Operating Company, Inc. | Surface display of proteins on recombinant bacteria and uses thereof |
WO2024064200A2 (en) * | 2022-09-20 | 2024-03-28 | The Texas A&M University System | Darpin-containing compositions and methods thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5055400A (en) | 1986-11-26 | 1991-10-08 | University Of Guelph | Leukotoxin gene of pasteurella haemolytica |
US4957739A (en) | 1987-08-13 | 1990-09-18 | Board Of Regents, The University Of Texas System | Pharmaceutical compositions of a 105 kD P. Haemolytica derived antigen useful for treatment of Shipping Fever |
CA2014033C (en) | 1989-04-07 | 1993-02-09 | Stephen D. Acres | Compositions and treatments for pneumonia in animals |
AU642650B2 (en) * | 1990-04-05 | 1993-10-28 | University Of Saskatchewan | Compositions and treatments for pneumonia in animals |
US5594107A (en) * | 1990-08-22 | 1997-01-14 | University Of Saskatchewan | Chimeric protein comprising an RTX-family cytotoxin and interferon-2 or interferon |
US5273889A (en) | 1990-08-22 | 1993-12-28 | University Of Saskatchewan | Gamma-iterferon-leukotoxin gene fusions and uses thereof |
US5238823A (en) | 1990-08-22 | 1993-08-24 | Veterinary Infectious Disease Organization | Interleukin-2-leukotoxin gene fusions and uses thereof |
US6797272B1 (en) | 1991-10-16 | 2004-09-28 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
US5422110A (en) | 1991-10-16 | 1995-06-06 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
US5837268A (en) * | 1991-10-16 | 1998-11-17 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
US5723129A (en) | 1991-10-16 | 1998-03-03 | University Of Saskatchewan | GnRH-leukotoxin chimeras |
WO1993008290A1 (en) | 1991-10-16 | 1993-04-29 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
AU2562897A (en) | 1996-04-23 | 1997-11-12 | University Of British Columbia, The | Pathogenic (escherichia coli) associated protein |
AU1137399A (en) | 1997-11-12 | 1999-05-31 | University Of British Columbia, The | Hp90: host membrane receptor for pathogenic bacteria, encoded by the bacterial tir gene |
NZ509137A (en) * | 1998-06-04 | 2004-01-30 | Metamorphix Internat Inc | Methods for reducing GnRH levels in prepubertal vertebrates as an alternative to surgical sterilisation |
US6365723B1 (en) | 1998-12-04 | 2002-04-02 | Wisconsin Alumni Research Foundation | Sequences of E. coli O157 |
BR0206312A (pt) * | 2001-01-04 | 2004-02-17 | Univ Saskatchewan | Composição de vacina, uso sobrenadante de cultura celular de escherichia coli enteroemorrágica (ehec), e, métodos para a geração de uma resposta imunológica em um mamìfero contra um antìgeno de escherichia coli enteroemorrágica (ehec) secretado, e 0157:h7 enteroemorrágica (ehec 0157:h7) secretado, e para a redução da colonização de escherichia coli enteroemorrágica (ehec) em um ruminante |
AU2002347314A1 (en) * | 2002-11-29 | 2004-06-23 | Imperial College Innovations Limited | Vaccine against enteropathogenic and enterohaemorragic escherichia coli |
WO2007101337A1 (en) * | 2006-03-06 | 2007-09-13 | Bioniche Life Sciences Inc. | Methods and compositions comprising bacterial type hi secreted proteins for mucosal immunization of animals |
AU2007240614B2 (en) * | 2006-04-20 | 2013-09-12 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine Incorporated | Methods and compositions based on Shiga toxin type 1 protein |
-
2010
- 2010-04-06 CA CA2757828A patent/CA2757828C/en active Active
- 2010-04-06 JP JP2012503839A patent/JP2012522522A/ja active Pending
- 2010-04-06 AU AU2010234193A patent/AU2010234193B2/en active Active
- 2010-04-06 WO PCT/CA2010/000516 patent/WO2010115278A1/en active Application Filing
- 2010-04-06 US US13/262,444 patent/US8734811B2/en active Active
- 2010-04-06 EP EP10761153.5A patent/EP2417165B1/en active Active
- 2010-04-06 BR BRPI1014505A patent/BRPI1014505B1/pt active IP Right Grant
-
2015
- 2015-09-02 JP JP2015172551A patent/JP2016029049A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2417165A4 (en) | 2013-02-13 |
WO2010115278A1 (en) | 2010-10-14 |
EP2417165A1 (en) | 2012-02-15 |
CA2757828C (en) | 2019-01-08 |
EP2417165B1 (en) | 2016-05-25 |
WO2010115278A8 (en) | 2010-12-02 |
CA2757828A1 (en) | 2010-10-14 |
JP2016029049A (ja) | 2016-03-03 |
US20120087939A1 (en) | 2012-04-12 |
AU2010234193A1 (en) | 2011-11-03 |
BRPI1014505B1 (pt) | 2020-02-04 |
BRPI1014505A8 (pt) | 2017-07-11 |
AU2010234193B2 (en) | 2015-08-20 |
US8734811B2 (en) | 2014-05-27 |
JP2012522522A (ja) | 2012-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: UNIVERSITY OF SASKATCHEWAN (CA) , TELESTA THERAPEUTICS INC. (CA) Owner name: UNIVERSITY OF SASKATCHEWAN (CA) , TELESTA THERAPEU |
|
B25A | Requested transfer of rights approved |
Owner name: UNIVERSITY OF SASKATCHEWAN (CA) |
|
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI. |
|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/04/2010, OBSERVADAS AS CONDICOES LEGAIS. |