CA2757686C - Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (ghb) in a sample - Google Patents

Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (ghb) in a sample Download PDF

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Publication number
CA2757686C
CA2757686C CA2757686A CA2757686A CA2757686C CA 2757686 C CA2757686 C CA 2757686C CA 2757686 A CA2757686 A CA 2757686A CA 2757686 A CA2757686 A CA 2757686A CA 2757686 C CA2757686 C CA 2757686C
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Canada
Prior art keywords
ghb
cofactor
sample
concentration
enzyme
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CA2757686A
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English (en)
French (fr)
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CA2757686A1 (en
Inventor
Lara Hasan
Michel-Angelo Sciotti
Thomas Jermann
Jakob Matthias Weber
Daniel Gygax
Andre Scholer
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Buehlmann Laboratories AG
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2757686A 2009-04-28 2010-04-23 Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (ghb) in a sample Active CA2757686C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09005884.3A EP2253711B1 (en) 2009-04-28 2009-04-28 Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (GHB) in a sample
EP09005884.3 2009-04-28
PCT/EP2010/055436 WO2010124999A1 (en) 2009-04-28 2010-04-23 Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (ghb) in a sample

Publications (2)

Publication Number Publication Date
CA2757686A1 CA2757686A1 (en) 2010-11-04
CA2757686C true CA2757686C (en) 2018-07-24

Family

ID=40740184

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2757686A Active CA2757686C (en) 2009-04-28 2010-04-23 Methods, compositions and a kit suitable for determining the concentration of gamma-hydroxy butyric acid (ghb) in a sample

Country Status (7)

Country Link
US (1) US8609359B2 (enExample)
EP (1) EP2253711B1 (enExample)
JP (1) JP5711216B2 (enExample)
KR (1) KR20120015327A (enExample)
CN (1) CN102405294A (enExample)
CA (1) CA2757686C (enExample)
WO (1) WO2010124999A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2649443A2 (en) 2010-12-06 2013-10-16 Ramot at Tel-Aviv University Ltd Methods and kits for detection of drugs
GB201116420D0 (en) * 2011-09-23 2011-11-02 Univ Strathclyde GHB detection
CN104111253A (zh) * 2014-06-20 2014-10-22 武汉高丰生物科技有限公司 一种抗抗坏血酸和色素干扰的4-羟基丁酸检测试纸的制备方法
CN104713874B (zh) * 2015-03-05 2016-08-31 杭州欣叶生物科技有限公司 乳腺癌尿液检测试剂和检测试剂盒及其制备和检测方法
CN104897667B (zh) * 2015-06-19 2017-10-03 公安部物证鉴定中心 Smith试剂在检测液体检材中GHB中的应用
CN107014939B (zh) * 2017-02-27 2018-06-08 南京市公安局刑事侦查局 离子排斥-离子交换柱切换联用测定尿液中的γ-羟基丁酸的方法
CN111208247A (zh) * 2020-01-08 2020-05-29 浙江工业大学 在线热辅助甲基化-气相色谱质谱法测定人体毛发中γ-羟基丁酸含量的方法
KR20210091996A (ko) 2020-01-15 2021-07-23 금오공과대학교 산학협력단 감마-히드록시뷰티릭산 감지 물질이 도포된 섬유를 포함하는 감지키트 및 이의 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6091998A (ja) * 1983-10-27 1985-05-23 Yukio Shigeta 体液及び尿中のｄ―３―ヒドロキシ酪酸の測定法並びにそのための測定試薬
US6153147A (en) * 1998-10-06 2000-11-28 Craig; James J. Beverage analysis sample
US20050233459A1 (en) * 2003-11-26 2005-10-20 Melker Richard J Marker detection method and apparatus to monitor drug compliance
US20010046710A1 (en) * 2000-02-04 2001-11-29 Cutler Charlyne E. Narcotics detector test strips for a beverage
US6617123B1 (en) * 2000-06-29 2003-09-09 Jack V. Smith Method for detection of 4-hydroxybutyric acid and its precursor(s) in fluids
US6703216B2 (en) * 2002-03-14 2004-03-09 The Regents Of The University Of California Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
CN1962876A (zh) * 2006-11-13 2007-05-16 于永光 酶法测定d－3－羟基丁酸试剂盒

Also Published As

Publication number Publication date
CA2757686A1 (en) 2010-11-04
EP2253711B1 (en) 2014-01-01
WO2010124999A1 (en) 2010-11-04
US8609359B2 (en) 2013-12-17
JP2012525127A (ja) 2012-10-22
JP5711216B2 (ja) 2015-04-30
KR20120015327A (ko) 2012-02-21
EP2253711A1 (en) 2010-11-24
CN102405294A (zh) 2012-04-04
US20120052520A1 (en) 2012-03-01

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