CA2751581A1 - Compositions and methods for extended therapy with aminopyridines - Google Patents

Compositions and methods for extended therapy with aminopyridines Download PDF

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Publication number
CA2751581A1
CA2751581A1 CA2751581A CA2751581A CA2751581A1 CA 2751581 A1 CA2751581 A1 CA 2751581A1 CA 2751581 A CA2751581 A CA 2751581A CA 2751581 A CA2751581 A CA 2751581A CA 2751581 A1 CA2751581 A1 CA 2751581A1
Authority
CA
Canada
Prior art keywords
aminopyridine
patient
timed
treatment
walk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2751581A
Other languages
English (en)
French (fr)
Inventor
Andrew R. Blight
Ron Cohen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acorda Therapeutics Inc
Original Assignee
Acorda Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42562065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2751581(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Acorda Therapeutics Inc filed Critical Acorda Therapeutics Inc
Publication of CA2751581A1 publication Critical patent/CA2751581A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CA2751581A 2009-02-11 2010-02-11 Compositions and methods for extended therapy with aminopyridines Abandoned CA2751581A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US15167909P 2009-02-11 2009-02-11
US61/151,679 2009-02-11
US25956309P 2009-11-09 2009-11-09
US61/259,563 2009-11-09
US28587209P 2009-12-11 2009-12-11
US61/285,872 2009-12-11
US28895309P 2009-12-22 2009-12-22
US61/288,953 2009-12-22
US29925910P 2010-01-28 2010-01-28
US61/299,259 2010-01-28
PCT/US2010/023970 WO2010093839A1 (en) 2009-02-11 2010-02-11 Compositions and methods for extended therapy with aminopyridines

Publications (1)

Publication Number Publication Date
CA2751581A1 true CA2751581A1 (en) 2010-08-19

Family

ID=42562065

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2751581A Abandoned CA2751581A1 (en) 2009-02-11 2010-02-11 Compositions and methods for extended therapy with aminopyridines

Country Status (22)

Country Link
US (3) US20120029035A1 (enExample)
JP (1) JP2012517449A (enExample)
KR (3) KR20180114250A (enExample)
CN (2) CN101896182A (enExample)
AR (1) AR075413A1 (enExample)
AU (2) AU2010213663A1 (enExample)
BR (2) BRPI1000030A2 (enExample)
CA (1) CA2751581A1 (enExample)
CL (1) CL2011001927A1 (enExample)
CO (1) CO6440534A2 (enExample)
EA (1) EA022755B1 (enExample)
EC (1) ECSP11011311A (enExample)
IL (1) IL214500A0 (enExample)
MX (1) MX2011008485A (enExample)
NI (1) NI201100155A (enExample)
NZ (1) NZ595046A (enExample)
PE (1) PE20120791A1 (enExample)
SG (2) SG173641A1 (enExample)
TN (1) TN2011000403A1 (enExample)
TW (2) TW201034665A (enExample)
UY (2) UY32445A (enExample)
WO (2) WO2010093839A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
US20150111930A1 (en) * 2013-10-23 2015-04-23 Afgin Pharma, Llc Topical regional neuro-affective therapy
TW201125562A (en) * 2009-09-04 2011-08-01 Acorda Therapeutics Inc Sustained release fampridine treatment in patients with multiple sclerosis
CN102442942A (zh) * 2010-10-08 2012-05-09 天津和美生物技术有限公司 4-氨基吡啶的多晶型物及其制备和应用
BR112013019265A2 (pt) * 2011-01-28 2016-10-11 Acorda Therapeutics Inc uso de bloqueadores do canal de potássio no tratamento da paralisia cerebral
EP2814492A1 (en) * 2012-02-13 2014-12-24 Acorda Therapeutics, Inc. Methods for treating an impairment in gait and/or balance in patients with multiple sclerosis using an aminopyridine
WO2014028387A1 (en) * 2012-08-13 2014-02-20 Acorda Therapeutics, Inc. Methods for improving walking capacity in patients with multiple sclerosis using an aminopyridine
US11145417B2 (en) * 2014-02-04 2021-10-12 Optimata Ltd. Method and system for prediction of medical treatment effect
RU2580837C1 (ru) * 2015-05-05 2016-04-10 Федеральное Государственное Автономное Образовательное Учреждение Высшего Профессионального Образования "Московский Физико-Технический Институт (Государственный Университет)" Кристаллогидрат 4-аминопиридина, способ его получения, фармацевтическая композиция и способ лечения и/или профилактики на её основе
TWI679012B (zh) * 2015-09-11 2019-12-11 法德生技藥品股份有限公司 含有達方吡啶的緩釋口服滲透錠劑及其用途
WO2022124946A1 (ru) * 2020-12-10 2022-06-16 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые полиморфные формы 4-аминопиридина и их фармацевтическое применение
CN112914884B (zh) * 2021-01-19 2022-02-11 重庆火后草科技有限公司 通过稳态时长置信度测量睡眠状态下的体重值的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE82916B1 (en) * 1990-11-02 2003-06-11 Elan Corp Plc Formulations and their use in the treatment of neurological diseases
US6288026B1 (en) * 1999-02-24 2001-09-11 Heinrich Exner Process and composition for treating diseases with an oil-in-water emulsion
US8007826B2 (en) * 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions

Also Published As

Publication number Publication date
PE20120791A1 (es) 2012-07-08
EA201171043A1 (ru) 2012-02-28
WO2010093838A1 (en) 2010-08-19
TW201032809A (en) 2010-09-16
NI201100155A (es) 2012-02-16
UY32444A (es) 2010-09-30
CN101896182A (zh) 2010-11-24
SG173641A1 (en) 2011-09-29
CL2011001927A1 (es) 2012-07-20
AU2016219650C1 (en) 2018-08-23
NZ595046A (en) 2013-10-25
TN2011000403A1 (en) 2013-03-27
CN102046174A (zh) 2011-05-04
KR20170034452A (ko) 2017-03-28
TW201034665A (en) 2010-10-01
US20150313886A1 (en) 2015-11-05
KR20180114250A (ko) 2018-10-17
EA022755B1 (ru) 2016-02-29
JP2012517449A (ja) 2012-08-02
CO6440534A2 (es) 2012-05-15
KR20120000560A (ko) 2012-01-02
SG10201609184PA (en) 2016-12-29
BRPI1000031A2 (pt) 2018-02-14
AU2010213663A1 (en) 2011-09-29
US20120029035A1 (en) 2012-02-02
AR075413A1 (es) 2011-03-30
US20170319562A1 (en) 2017-11-09
ECSP11011311A (es) 2011-10-31
AU2016219650A1 (en) 2016-09-15
MX2011008485A (es) 2011-11-04
WO2010093839A1 (en) 2010-08-19
IL214500A0 (en) 2011-09-27
BRPI1000030A2 (pt) 2018-02-14
AU2016219650B2 (en) 2018-05-10
UY32445A (es) 2010-09-30

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150210

FZDE Discontinued

Effective date: 20210831