CA2744699A1 - Device and methods for subcutaneous delivery of high viscosity fluids - Google Patents
Device and methods for subcutaneous delivery of high viscosity fluids Download PDFInfo
- Publication number
- CA2744699A1 CA2744699A1 CA2744699A CA2744699A CA2744699A1 CA 2744699 A1 CA2744699 A1 CA 2744699A1 CA 2744699 A CA2744699 A CA 2744699A CA 2744699 A CA2744699 A CA 2744699A CA 2744699 A1 CA2744699 A1 CA 2744699A1
- Authority
- CA
- Canada
- Prior art keywords
- needle
- infusion system
- fluid
- therapeutic
- infusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000012530 fluid Substances 0.000 title claims abstract description 130
- 238000007920 subcutaneous administration Methods 0.000 title claims abstract description 43
- 238000000034 method Methods 0.000 title claims abstract description 42
- 238000001802 infusion Methods 0.000 claims abstract description 105
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 72
- 239000003814 drug Substances 0.000 claims description 36
- 239000000203 mixture Substances 0.000 claims description 36
- 238000004891 communication Methods 0.000 claims description 24
- 229940079593 drug Drugs 0.000 claims description 21
- 108010003272 Hyaluronate lyase Proteins 0.000 claims description 10
- 102000009066 Hyaluronoglucosaminidase Human genes 0.000 claims description 10
- 210000001015 abdomen Anatomy 0.000 claims description 8
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- 230000037361 pathway Effects 0.000 claims description 7
- 101000585728 Homo sapiens Protein O-GlcNAcase Proteins 0.000 claims description 4
- 102000046319 human OGA Human genes 0.000 claims description 4
- 229960002773 hyaluronidase Drugs 0.000 claims description 4
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- 239000002246 antineoplastic agent Substances 0.000 claims 1
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- 230000000694 effects Effects 0.000 abstract description 16
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- 239000007924 injection Substances 0.000 description 12
- 210000004304 subcutaneous tissue Anatomy 0.000 description 12
- 229940055240 carimune Drugs 0.000 description 8
- 229920002674 hyaluronan Polymers 0.000 description 8
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 description 8
- 229940099552 hyaluronan Drugs 0.000 description 8
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- 238000013461 design Methods 0.000 description 6
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- 239000008223 sterile water Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 238000005206 flow analysis Methods 0.000 description 4
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- 230000006806 disease prevention Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000007515 enzymatic degradation Effects 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000005038 ethylene vinyl acetate Substances 0.000 description 1
- 230000036251 extravasation Effects 0.000 description 1
- 210000003195 fascia Anatomy 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
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- 238000001727 in vivo Methods 0.000 description 1
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- 230000037368 penetrate the skin Effects 0.000 description 1
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- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 210000001179 synovial fluid Anatomy 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/324,562 | 2008-11-26 | ||
| US12/324,562 US20100130958A1 (en) | 2008-11-26 | 2008-11-26 | Device and Methods for Subcutaneous Delivery of High Viscosity Fluids |
| PCT/US2009/065813 WO2010062919A1 (en) | 2008-11-26 | 2009-11-24 | Device and methods for subcutaneous delivery of high viscosity fluids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2744699A1 true CA2744699A1 (en) | 2010-06-03 |
Family
ID=42196986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2744699A Abandoned CA2744699A1 (en) | 2008-11-26 | 2009-11-24 | Device and methods for subcutaneous delivery of high viscosity fluids |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100130958A1 (enExample) |
| EP (1) | EP2358414A4 (enExample) |
| JP (1) | JP2012509749A (enExample) |
| KR (1) | KR20110092327A (enExample) |
| CN (1) | CN102227229A (enExample) |
| BR (1) | BRPI0922825A2 (enExample) |
| CA (1) | CA2744699A1 (enExample) |
| RU (1) | RU2011126201A (enExample) |
| WO (1) | WO2010062919A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011130107A2 (en) | 2010-04-16 | 2011-10-20 | Surgivision, Inc. | Mri surgical systems including mri-compatible surgical cannulae for transferring a substance to and/or from a patient |
| US10245421B2 (en) | 2010-04-28 | 2019-04-02 | Sorrento Therapeutics, Inc. | Nanopatterned medical device with enhanced cellular interaction |
| JP5981442B2 (ja) * | 2010-11-24 | 2016-08-31 | アシスト・メディカル・システムズ，インコーポレイテッド | 造影剤注入シリンジの入口弁システム |
| CN104039382B (zh) | 2011-10-27 | 2018-01-12 | 金伯利-克拉克环球有限公司 | 高粘度生物活性剂的经皮递送 |
| EP3542851B1 (en) | 2011-10-27 | 2021-12-15 | Sorrento Therapeutics, Inc. | Implantable devices for delivery of bioactive agents |
| US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
| US20150217058A1 (en) | 2012-09-24 | 2015-08-06 | Enable Injections, Llc | Medical vial and injector assemblies and methods of use |
| US9265925B2 (en) | 2012-10-16 | 2016-02-23 | Acist Medical Systems, Inc. | Controlling flow in a medical injection system |
| US20170128059A1 (en) * | 2013-01-08 | 2017-05-11 | Prescient Surgical, Inc. | Methods and apparatus for prevention of surgical site infections |
| WO2014204894A2 (en) | 2013-06-18 | 2014-12-24 | Enable Injections, Llc | Vial transfer and injection apparatus and method |
| KR102320331B1 (ko) * | 2013-08-27 | 2021-11-03 | 레프로-메드 시스템즈, 인코포레이티드 | 피하 치료를 위한 바늘을 선택하는 방법 |
| US9891296B2 (en) * | 2013-09-13 | 2018-02-13 | MRI Interventions, Inc. | Intrabody fluid transfer devices, systems and methods |
| WO2017142698A1 (en) | 2016-02-17 | 2017-08-24 | MRI Interventions, Inc. | Intrabody surgical fluid transfer assemblies with adjustable exposed cannula to needle tip length, related systems and methods |
| WO2019094502A1 (en) | 2017-11-07 | 2019-05-16 | Prescient Surgical, Inc. | Methods and apparatus for prevention of surgical site infection |
| US20190201620A1 (en) * | 2017-12-29 | 2019-07-04 | Repro-Med Systems, Inc. | High flow at low pressure infusion system and method |
| EP3781074A1 (en) | 2018-05-09 | 2021-02-24 | ClearPoint Neuro, Inc. | Mri compatible intrabody fluid transfer systems and related devices and methods |
| US11253237B2 (en) | 2018-05-09 | 2022-02-22 | Clearpoint Neuro, Inc. | MRI compatible intrabody fluid transfer systems and related devices and methods |
| US11684750B2 (en) | 2019-10-08 | 2023-06-27 | Clearpoint Neuro, Inc. | Extension tube assembly and related medical fluid transfer systems and methods |
| WO2021154926A1 (en) | 2020-01-30 | 2021-08-05 | Acist Medical Systems, Inc. | Valve assembly |
| US11560964B2 (en) | 2020-08-21 | 2023-01-24 | Acist Medical Systems, Inc. | Valve actuation device coupling |
| WO2024138188A1 (en) | 2022-12-22 | 2024-06-27 | Halozyme, Inc. | Hyaluronidase enzyme formulations for high volume administration |
| WO2025081072A1 (en) * | 2023-10-13 | 2025-04-17 | Halozyme, Inc. | Prefilled autoinfusion device |
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| US4235234A (en) * | 1978-11-30 | 1980-11-25 | Martin John K Iii | Subcutaneous injection system |
| FR2453306B1 (fr) * | 1979-04-06 | 1986-03-14 | Dba | Dispositif d'actionnement hydraulique a cinq positions |
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| CN101087625B (zh) * | 2004-11-22 | 2012-02-22 | 因特利杰克特有限公司 | 用于药物供给的装置和系统 |
| US7648482B2 (en) * | 2004-11-22 | 2010-01-19 | Intelliject, Inc. | Devices, systems, and methods for medicament delivery |
| WO2006123329A2 (en) * | 2005-05-17 | 2006-11-23 | Medingo Ltd. | Disposable dispenser for patient infusion |
| EP2063934A1 (en) * | 2006-09-18 | 2009-06-03 | Agency for Science, Technology and Research | Needle structures and methods for fabricating needle structures |
-
2008
- 2008-11-26 US US12/324,562 patent/US20100130958A1/en not_active Abandoned
-
2009
- 2009-11-24 JP JP2011538680A patent/JP2012509749A/ja not_active Withdrawn
- 2009-11-24 KR KR1020117014657A patent/KR20110092327A/ko not_active Withdrawn
- 2009-11-24 RU RU2011126201/14A patent/RU2011126201A/ru not_active Application Discontinuation
- 2009-11-24 CA CA2744699A patent/CA2744699A1/en not_active Abandoned
- 2009-11-24 EP EP09829770.8A patent/EP2358414A4/en not_active Withdrawn
- 2009-11-24 CN CN2009801473832A patent/CN102227229A/zh active Pending
- 2009-11-24 BR BRPI0922825A patent/BRPI0922825A2/pt not_active IP Right Cessation
- 2009-11-24 WO PCT/US2009/065813 patent/WO2010062919A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2358414A1 (en) | 2011-08-24 |
| RU2011126201A (ru) | 2013-01-10 |
| CN102227229A (zh) | 2011-10-26 |
| BRPI0922825A2 (pt) | 2015-12-29 |
| WO2010062919A1 (en) | 2010-06-03 |
| EP2358414A4 (en) | 2013-04-24 |
| US20100130958A1 (en) | 2010-05-27 |
| JP2012509749A (ja) | 2012-04-26 |
| KR20110092327A (ko) | 2011-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20141125 |