CA2742595C - Dried and irradiated skin equivalents for ready use - Google Patents
Dried and irradiated skin equivalents for ready use Download PDFInfo
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- CA2742595C CA2742595C CA2742595A CA2742595A CA2742595C CA 2742595 C CA2742595 C CA 2742595C CA 2742595 A CA2742595 A CA 2742595A CA 2742595 A CA2742595 A CA 2742595A CA 2742595 C CA2742595 C CA 2742595C
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/105—Skin implants, e.g. artificial skin
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
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- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
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- Cell Biology (AREA)
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- Molecular Biology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (3)
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| US11115308P | 2008-11-04 | 2008-11-04 | |
| US61/111,153 | 2008-11-04 | ||
| PCT/US2009/063217 WO2010053948A1 (en) | 2008-11-04 | 2009-11-04 | Dried and irradiated skin equivalents for ready use |
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| CA2742595A1 CA2742595A1 (en) | 2010-05-14 |
| CA2742595C true CA2742595C (en) | 2014-04-01 |
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| PT2352472T (pt) | 2008-11-04 | 2017-04-11 | Stratatech Corp | Equivalentes de pele secos e irradiados prontos a utilizar |
| WO2010135655A2 (en) | 2009-05-21 | 2010-11-25 | Stratatech Corporation | Human skin substitutes expressing il-12 |
| CA2905656C (en) * | 2013-03-13 | 2020-04-14 | Stratatech Corporation | Cryopreservation of viable human skin substitutes |
| KR101701396B1 (ko) | 2014-10-28 | 2017-02-01 | 주식회사 엑티저 | 오디오 신호 처리 장치 및 방법 |
| US20220287298A1 (en) * | 2017-01-27 | 2022-09-15 | Stratatech Corporation | Tissue container systems |
| US20220347353A1 (en) * | 2019-09-27 | 2022-11-03 | Stratatech Corporation | Methods for treating acute wounds and improving outcomes |
| EP4150053A4 (en) * | 2020-05-13 | 2024-06-19 | Stratatech Corporation | VIABLE BIOTECHNOLOGICALLY ENGINEERED SKIN CONSTRUCTS |
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| US4485096A (en) * | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
| IL95429A (en) * | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
| ATE161408T1 (de) * | 1990-04-24 | 1998-01-15 | Mark Eisenberg | Zusammengesetztes äquivalent der lebenden haut |
| US6126935A (en) * | 1991-11-20 | 2000-10-03 | N.V. Innogenetics S.A. | Pellets obtained from cell cultures of keratinocytes and their use in wound healing |
| US6585969B1 (en) * | 1991-11-20 | 2003-07-01 | N. V. Innogenetics S.A. | Non-viable keratinocyte cell composition or lysate for promoting wound healing |
| JPH10509610A (ja) * | 1994-11-09 | 1998-09-22 | クリ・ハークチ，ワリド | 創傷修復用包帯およびそれらの保存法 |
| US5693332C1 (en) * | 1995-08-11 | 2001-01-09 | Univ California | Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure |
| JP3377354B2 (ja) * | 1995-12-25 | 2003-02-17 | 株式会社メニコン | 人工皮膚 |
| US5968546A (en) * | 1997-05-16 | 1999-10-19 | Baur; Marcus | Keratinocyte culture from precursor cells |
| US5989837A (en) * | 1998-07-13 | 1999-11-23 | Wisconsin Alumni Research Foundation | Immortalized human keratinocyte cell line |
| JP3738273B2 (ja) * | 1999-07-20 | 2006-01-25 | ディーエフビー ファーマシューティカルズ， インコーポレイテッド | 改良ケラチノサイト培養物およびその使用 |
| US6866686B2 (en) * | 2000-01-28 | 2005-03-15 | Cryolife, Inc. | Tissue graft |
| NZ549526A (en) * | 2001-03-02 | 2009-06-26 | Stratatech Corp | Human skin equivalents comprising near diploid immortalized keratinocyte cells (NIKS) |
| US6974697B2 (en) * | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
| JP4753577B2 (ja) * | 2002-04-30 | 2011-08-24 | ストラタテック コーポレーション | 外因性血管新生増殖因子を発現するケラチノサイト |
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| US7993922B2 (en) * | 2002-10-18 | 2011-08-09 | Reliance Life Sciences Pvt. Ltd. | Three-dimensional tissue equivalent using macromass culture |
| CA2527822A1 (en) * | 2003-05-30 | 2004-12-23 | Stratatech Corporation | Room temperature storage of organs |
| CA2758178C (en) | 2003-08-01 | 2016-10-11 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| US7674291B2 (en) * | 2003-08-01 | 2010-03-09 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| WO2005079821A1 (en) * | 2004-02-13 | 2005-09-01 | Intercytex Limited | Wound healing profile |
| US20060141627A1 (en) * | 2004-11-18 | 2006-06-29 | Stratatech Corporation | Vectors for stable gene expression |
| CA2600177C (en) | 2005-03-01 | 2011-06-14 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| CA2601595C (en) | 2005-03-17 | 2015-02-24 | Stratatech Corporation | Skin substitutes with improved purity |
| CN100400655C (zh) | 2005-12-02 | 2008-07-09 | 王平安 | 组织工程化细胞外基质的制备方法 |
| NO2215212T3 (OSRAM) * | 2007-11-14 | 2018-01-27 | ||
| PT2352472T (pt) | 2008-11-04 | 2017-04-11 | Stratatech Corp | Equivalentes de pele secos e irradiados prontos a utilizar |
| WO2010135655A2 (en) | 2009-05-21 | 2010-11-25 | Stratatech Corporation | Human skin substitutes expressing il-12 |
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| EP2352472B1 (en) | 2017-01-04 |
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| US8685463B2 (en) | 2014-04-01 |
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