CA2742107A1 - Method of producing serum-free insulin-free factor vii - Google Patents

Method of producing serum-free insulin-free factor vii Download PDF

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Publication number
CA2742107A1
CA2742107A1 CA2742107A CA2742107A CA2742107A1 CA 2742107 A1 CA2742107 A1 CA 2742107A1 CA 2742107 A CA2742107 A CA 2742107A CA 2742107 A CA2742107 A CA 2742107A CA 2742107 A1 CA2742107 A1 CA 2742107A1
Authority
CA
Canada
Prior art keywords
insulin
free
serum
cells
media
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2742107A
Other languages
English (en)
French (fr)
Inventor
Simone Von Fircks
Ruth Elmer
Manfred Reiter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare SA
Baxter International Inc
Original Assignee
Baxter Healthcare SA
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42165541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2742107(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Baxter Healthcare SA, Baxter International Inc filed Critical Baxter Healthcare SA
Publication of CA2742107A1 publication Critical patent/CA2742107A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C12N2500/95—Protein-free medium and culture conditions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2742107A 2008-11-12 2009-11-05 Method of producing serum-free insulin-free factor vii Abandoned CA2742107A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11379208P 2008-11-12 2008-11-12
US61/113,792 2008-11-12
PCT/US2009/063338 WO2010056584A1 (en) 2008-11-12 2009-11-05 Method of producing serum-free insulin-free factor vii

Publications (1)

Publication Number Publication Date
CA2742107A1 true CA2742107A1 (en) 2010-05-20

Family

ID=42165541

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2742107A Abandoned CA2742107A1 (en) 2008-11-12 2009-11-05 Method of producing serum-free insulin-free factor vii

Country Status (15)

Country Link
US (1) US20100120093A1 (https=)
EP (2) EP2356247B2 (https=)
JP (1) JP5719301B2 (https=)
AU (1) AU2009314345B2 (https=)
CA (1) CA2742107A1 (https=)
DK (1) DK2356247T4 (https=)
ES (1) ES2547881T5 (https=)
HK (1) HK1219113A1 (https=)
HR (1) HRP20151054T4 (https=)
HU (1) HUE026210T2 (https=)
IL (1) IL212355A (https=)
PL (1) PL2356247T5 (https=)
PT (1) PT2356247E (https=)
SI (1) SI2356247T2 (https=)
WO (1) WO2010056584A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013535981A (ja) * 2010-08-20 2013-09-19 ワイス・エルエルシー 成長因子不含適合細胞の細胞培養
US20120076779A1 (en) 2010-09-17 2012-03-29 Baxter Healthcare S.A. STABILIZATION OF IMMUNOGLOBULINS AND OTHER PROTEINS THROUGH AQUEOUS FORMULATIONS WITH SODIUM CHLORIDE AT WEAK ACIDIC TO NEUTRAL ph
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
AR095196A1 (es) 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
KR20150026024A (ko) * 2013-08-30 2015-03-11 한미약품 주식회사 인간 혈액응고 7인자 유도체의 대량 생산 방법
US11286292B2 (en) 2014-02-07 2022-03-29 Cmc Biologics A/S Bioreactor arrangement and continuous process for producing and capturing a biopolymer
NZ724826A (en) * 2014-04-16 2022-07-29 Cmc Biologics As A high cell density fill and draw fermentation process
AU2015269365A1 (en) 2014-06-04 2016-12-15 Amgen Inc. Methods for harvesting mammalian cell cultures
US12297451B1 (en) 2019-10-25 2025-05-13 Regeneron Pharmaceuticals, Inc. Cell culture medium

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456591A (en) 1981-06-25 1984-06-26 Baxter Travenol Laboratories, Inc. Therapeutic method for activating factor VII
GR860984B (en) 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
GB9022545D0 (en) * 1990-10-17 1990-11-28 Wellcome Found Culture medium
US5997864A (en) 1995-06-07 1999-12-07 Novo Nordisk A/S Modified factor VII
US5804420A (en) * 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium
AT407255B (de) * 1997-06-20 2001-02-26 Immuno Ag Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons
AT409379B (de) † 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
DK1200561T3 (da) † 1999-08-05 2006-10-16 Baxter Ag Rekombinant stabil celleklon, dens fremstilling og anvendelse
US20030204338A1 (en) 2002-04-22 2003-10-30 Peter Martinek Method and measurement probe for the performance of measurements in water supply systems
US20040185535A1 (en) † 2003-03-21 2004-09-23 Giles Wilson Industrial-scale serum-free production of recombinant FVII in mammalian cells
BR0114373A (pt) * 2000-10-02 2004-02-17 Novo Nordisk As Célula hospedeira eucariótica, métodos para a produção de fvii e de fviia ou de suas variantes, de uma proteìna dependente de vitamina k e de uma célula hospedeira eucariótica produtora de fvii ou de seu análogo, vetor recombinante, fvii e fviia recombinante ou suas variantes, e, proteìna dependente de vitamina k recombinante
EP1434857B1 (en) * 2001-10-02 2007-08-01 Novo Nordisk Health Care AG Method for production of recombinant proteins in eukaryote cells
US20050214289A1 (en) * 2004-03-26 2005-09-29 Human Genome Sciences, Inc. Antibodies against Nogo receptor
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
EP1851305B1 (en) * 2005-02-11 2012-01-18 Novo Nordisk Health Care AG Production of a polypeptide in a serum-free cell culture liquid containing plant protein hydrolysate
CN101300342A (zh) † 2005-11-02 2008-11-05 惠氏公司 用于使哺乳动物细胞具备适应性的方法
ES2474573T3 (es) † 2006-01-04 2014-07-09 Baxter International Inc Medio de cultivo celular sin oligop�ptidos

Also Published As

Publication number Publication date
PL2356247T5 (pl) 2019-10-31
SI2356247T1 (sl) 2015-11-30
HK1219113A1 (en) 2017-03-24
PT2356247E (pt) 2015-10-26
EP2977461A1 (en) 2016-01-27
JP2012508562A (ja) 2012-04-12
IL212355A0 (en) 2011-06-30
US20100120093A1 (en) 2010-05-13
JP5719301B2 (ja) 2015-05-13
ES2547881T5 (es) 2019-10-16
AU2009314345B2 (en) 2015-02-12
EP2356247A4 (en) 2013-01-02
PL2356247T3 (pl) 2016-04-29
WO2010056584A1 (en) 2010-05-20
SI2356247T2 (sl) 2019-08-30
EP2356247A1 (en) 2011-08-17
IL212355A (en) 2016-04-21
HRP20151054T4 (hr) 2019-11-15
EP2356247B2 (en) 2019-05-15
EP2356247B1 (en) 2015-07-15
HRP20151054T1 (xx) 2015-11-20
HUE026210T2 (en) 2016-05-30
ES2547881T3 (es) 2015-10-09
AU2009314345A1 (en) 2011-06-30
DK2356247T3 (en) 2015-09-21
DK2356247T4 (da) 2019-06-03

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20151105