CA2738644A1 - Hepatitis c antibodies and uses thereof - Google Patents
Hepatitis c antibodies and uses thereof Download PDFInfo
- Publication number
- CA2738644A1 CA2738644A1 CA2738644A CA2738644A CA2738644A1 CA 2738644 A1 CA2738644 A1 CA 2738644A1 CA 2738644 A CA2738644 A CA 2738644A CA 2738644 A CA2738644 A CA 2738644A CA 2738644 A1 CA2738644 A1 CA 2738644A1
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- Prior art keywords
- hcv
- antibody
- antibodies
- cbh
- binding
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
- C07K16/109—Hepatitis C virus; Hepatitis G virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2008/078884 WO2010039154A1 (en) | 2008-10-05 | 2008-10-05 | Hepatitis c antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2738644A1 true CA2738644A1 (en) | 2010-05-08 |
Family
ID=42073762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2738644A Abandoned CA2738644A1 (en) | 2008-10-05 | 2008-10-05 | Hepatitis c antibodies and uses thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8858947B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2331573A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2012504602A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20110061624A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102197050A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008362482A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0823197A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2738644A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201170353A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL212040A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2011003613A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010039154A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2495256A4 (en) * | 2009-10-30 | 2013-09-25 | Toray Industries | ANTIBODIES HAVING INHIBITION ACTIVITY OF HEPATITIS C VIRUS (HCV) INFECTION AND USE THEREOF |
| WO2012107589A1 (en) * | 2011-02-11 | 2012-08-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment and prevention of hcv infections |
| JP6158171B2 (ja) | 2011-05-02 | 2017-07-05 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 合成ｃ型肝炎ゲノム、並びに、その製造方法及びその使用 |
| AU2013299986B2 (en) | 2012-08-07 | 2018-05-17 | Massachusetts Institute Of Technology | Anti-dengue virus antibodies and uses thereof |
| CN103113458B (zh) * | 2013-02-27 | 2014-08-20 | 北京大学人民医院 | 丙型肝炎病毒b细胞表位肽puhi34及其应用 |
| CN103172705B (zh) * | 2013-02-27 | 2014-08-20 | 北京大学人民医院 | 丙型肝炎病毒b细胞表位肽puhi16及其应用 |
| RU2539770C1 (ru) * | 2013-12-27 | 2015-01-27 | Татьяна Николаевна Власик | Способ нейтрализации вируса гепатита с, полностью человеческое моноклональное антитело против вируса гепатита с (варианты), композиция полностью человеческих моноклональных антител против вируса гепатита с и гибридная мышь/человек клеточная линия - продуцент полностью человеческих моноклональных антител против вируса гепатита с (варианты) |
| US9902764B2 (en) | 2014-02-11 | 2018-02-27 | Massachusetts Institute Of Technology | Full spectrum anti-dengue antibody |
| JPWO2015133467A1 (ja) * | 2014-03-06 | 2017-04-06 | 株式会社シノテスト | Ｃ型肝炎ウイルスのワクチン及び診断に用いるためのＨＢｃ／ＨＣＶ Ｅ２ペプチドキメラタンパク質 |
| CN104327170A (zh) * | 2014-05-16 | 2015-02-04 | 中国疾病预防控制中心病毒病预防控制所 | 丙型肝炎病毒(hcv)细胞进入抑制肽zte1序列及应用 |
| GB201415714D0 (en) * | 2014-09-05 | 2014-10-22 | Medical Res Council | Antibodies and antigen binding fragments thereof |
| CN105254756B (zh) * | 2015-11-27 | 2018-09-07 | 武汉大学 | 一种针对丙型肝炎病毒包膜蛋白e2的单克隆抗体及应用 |
| KR102640157B1 (ko) * | 2016-03-22 | 2024-02-27 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 인간화 항-클라우딘-1 항체 및 이의 용도 |
| CN107011435B (zh) * | 2016-06-01 | 2019-02-12 | 苏州银河生物医药有限公司 | 抗丙型肝炎病毒的全人单克隆抗体8d6 |
| EP4095156A1 (en) * | 2021-05-28 | 2022-11-30 | Universität zu Köln | Neutralizing antibodies against hepatitis c virus |
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| EP1127170A4 (en) * | 1998-11-05 | 2005-04-27 | Univ Leland Stanford Junior | HUMAN MONOCLONAL ANTIBODIES OF THE HEPATITIS C VIRUS (HCV) PAN |
| US7091324B2 (en) * | 1998-11-05 | 2006-08-15 | Board Of Trustees Of Leland Stanford Junior University | Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes |
| ES2529736T3 (es) * | 2003-04-10 | 2015-02-25 | Novartis Vaccines And Diagnostics, Inc. | Composición inmunogénica que comprende una proteína espicular del coronavirus del SARS |
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- 2008-10-05 KR KR1020117008883A patent/KR20110061624A/ko not_active Withdrawn
- 2008-10-05 EA EA201170353A patent/EA201170353A1/ru unknown
- 2008-10-05 AU AU2008362482A patent/AU2008362482A1/en not_active Abandoned
- 2008-10-05 US US13/122,598 patent/US8858947B2/en not_active Expired - Fee Related
- 2008-10-05 MX MX2011003613A patent/MX2011003613A/es unknown
- 2008-10-05 JP JP2011530033A patent/JP2012504602A/ja not_active Withdrawn
- 2008-10-05 BR BRPI0823197-4A patent/BRPI0823197A2/pt not_active IP Right Cessation
- 2008-10-05 CA CA2738644A patent/CA2738644A1/en not_active Abandoned
- 2008-10-05 EP EP08824626A patent/EP2331573A4/en not_active Withdrawn
- 2008-10-05 WO PCT/US2008/078884 patent/WO2010039154A1/en not_active Ceased
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| CN102197050A (zh) | 2011-09-21 |
| EA201170353A1 (ru) | 2011-12-30 |
| MX2011003613A (es) | 2011-08-03 |
| EP2331573A1 (en) | 2011-06-15 |
| AU2008362482A1 (en) | 2010-04-08 |
| US20120039846A1 (en) | 2012-02-16 |
| KR20110061624A (ko) | 2011-06-09 |
| IL212040A0 (en) | 2011-06-30 |
| US8858947B2 (en) | 2014-10-14 |
| EP2331573A4 (en) | 2012-09-05 |
| WO2010039154A1 (en) | 2010-04-08 |
| JP2012504602A (ja) | 2012-02-23 |
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