CA2731496A1 - Pyrazolopyridine kinase inhibitors - Google Patents
Pyrazolopyridine kinase inhibitors Download PDFInfo
- Publication number
- CA2731496A1 CA2731496A1 CA2731496A CA2731496A CA2731496A1 CA 2731496 A1 CA2731496 A1 CA 2731496A1 CA 2731496 A CA2731496 A CA 2731496A CA 2731496 A CA2731496 A CA 2731496A CA 2731496 A1 CA2731496 A1 CA 2731496A1
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Landscapes
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- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8294108P | 2008-07-23 | 2008-07-23 | |
| US61/082,941 | 2008-07-23 | ||
| PCT/US2009/051423 WO2010011762A1 (en) | 2008-07-23 | 2009-07-22 | Pyrazolopyridine kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2731496A1 true CA2731496A1 (en) | 2010-01-28 |
Family
ID=41203687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2731496A Abandoned CA2731496A1 (en) | 2008-07-23 | 2009-07-22 | Pyrazolopyridine kinase inhibitors |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120165368A1 (OSRAM) |
| EP (1) | EP2321318A1 (OSRAM) |
| JP (1) | JP5542287B2 (OSRAM) |
| CN (1) | CN102131808A (OSRAM) |
| AU (1) | AU2009274017A1 (OSRAM) |
| CA (1) | CA2731496A1 (OSRAM) |
| MX (1) | MX2011000834A (OSRAM) |
| WO (1) | WO2010011762A1 (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
| JP2011530527A (ja) * | 2008-08-06 | 2011-12-22 | バーテックス ファーマシューティカルズ インコーポレイテッド | アミノピリジンキナーゼ阻害剤 |
| DK2442809T3 (en) | 2009-06-17 | 2016-12-19 | Vertex Pharma | Inhibitors of the replication of influenza virus |
| MX2012008642A (es) * | 2010-01-27 | 2012-11-23 | Vertex Pharma | Inhibidores de cinasas de pirazolopiridinas. |
| CN102858769A (zh) * | 2010-01-27 | 2013-01-02 | 沃泰克斯药物股份有限公司 | 吡唑并吡啶激酶抑制剂 |
| AU2011343642A1 (en) | 2010-12-16 | 2013-05-02 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| EP3068776B1 (en) | 2013-11-13 | 2019-05-29 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| RS57541B1 (sr) | 2013-11-13 | 2018-10-31 | Vertex Pharma | Postupci za pripremu inhibitora replikacije virusa gripa |
| JP6704416B2 (ja) | 2015-05-13 | 2020-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | インフルエンザウイルスの複製の阻害剤を調製する方法 |
| MA42422A (fr) | 2015-05-13 | 2018-05-23 | Vertex Pharma | Inhibiteurs de la réplication des virus de la grippe |
| CN108794480A (zh) * | 2017-04-28 | 2018-11-13 | 天津药物研究院有限公司 | 吡咯并嘧啶类化合物、其制备方法和用途 |
| JP7536767B2 (ja) | 2018-12-31 | 2024-08-20 | バイオメア フュージョン，インコーポレイテッド | メニン－ｍｌｌ相互作用の不可逆的阻害剤 |
| US11174263B2 (en) | 2018-12-31 | 2021-11-16 | Biomea Fusion, Inc. | Inhibitors of menin-MLL interaction |
| CA3228627A1 (en) | 2021-08-11 | 2023-02-16 | Thomas Butler | Covalent inhibitors of menin-mll interaction for diabetes mellitus |
| KR20240087693A (ko) | 2021-08-20 | 2024-06-19 | 바이오메아 퓨전, 인크. | 암 치료를 위한 비가역적 메닌-mll 억제제인 n-[4-[4-(4-모르폴리닐)-7h-피롤로[2,3-d]피리미딘-6-일]페닐]-4-[[3(r)-[(1-옥소-2-프로펜-1-일)아미노]-1-피페리디닐]메틸]-2-피리딘카르복스아미드의 결정질 형태 |
| TW202430528A (zh) | 2023-01-18 | 2024-08-01 | 美商拜歐米富士恩股份有限公司 | Ｎ－［４－［４－（４－嗎啉基）－７ｈ－吡咯並［２，３－ｄ］嘧啶－６－基］苯基］－４－［［３（ｒ）－［（１－氧代－２－丙烯－１－基）氨基］－１－哌啶基］甲基］－２－吡啶甲醯胺的結晶形式作為ｍｅｎｉｎ－ｍｌｌ相互作用的共價抑制劑 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05001688A (es) * | 2002-08-12 | 2005-04-19 | Sugen Inc | 3-pirrolil-piridopirazoles y 3-pirrolil-indazoles como inhibidores de cinasa novedosos. |
| WO2005103050A2 (en) * | 2004-04-02 | 2005-11-03 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of rock and other protein kinases |
| ZA200704888B (en) * | 2004-11-22 | 2009-02-25 | Vertex Pharma | Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases |
-
2009
- 2009-07-22 CA CA2731496A patent/CA2731496A1/en not_active Abandoned
- 2009-07-22 CN CN2009801327342A patent/CN102131808A/zh active Pending
- 2009-07-22 EP EP09790732A patent/EP2321318A1/en not_active Withdrawn
- 2009-07-22 WO PCT/US2009/051423 patent/WO2010011762A1/en not_active Ceased
- 2009-07-22 AU AU2009274017A patent/AU2009274017A1/en not_active Abandoned
- 2009-07-22 MX MX2011000834A patent/MX2011000834A/es not_active Application Discontinuation
- 2009-07-22 JP JP2011520170A patent/JP5542287B2/ja not_active Expired - Fee Related
-
2011
- 2011-12-01 US US13/308,605 patent/US20120165368A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120165368A1 (en) | 2012-06-28 |
| WO2010011762A1 (en) | 2010-01-28 |
| JP2011529063A (ja) | 2011-12-01 |
| AU2009274017A1 (en) | 2010-01-28 |
| MX2011000834A (es) | 2011-04-05 |
| JP5542287B2 (ja) | 2014-07-09 |
| EP2321318A1 (en) | 2011-05-18 |
| CN102131808A (zh) | 2011-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20140722 |