CA2729124A1 - New i-crei derived single-chain meganuclease and uses thereof - Google Patents

New i-crei derived single-chain meganuclease and uses thereof Download PDF

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Publication number
CA2729124A1
CA2729124A1 CA2729124A CA2729124A CA2729124A1 CA 2729124 A1 CA2729124 A1 CA 2729124A1 CA 2729124 A CA2729124 A CA 2729124A CA 2729124 A CA2729124 A CA 2729124A CA 2729124 A1 CA2729124 A1 CA 2729124A1
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CA
Canada
Prior art keywords
crei
anyone
chain
meganuclease
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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CA2729124A
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English (en)
French (fr)
Inventor
Sylvestre Grizot
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Cellectis SA
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Cellectis SA
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Filing date
Publication date
Application filed by Cellectis SA filed Critical Cellectis SA
Publication of CA2729124A1 publication Critical patent/CA2729124A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2729124A 2008-01-31 2009-02-02 New i-crei derived single-chain meganuclease and uses thereof Abandoned CA2729124A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/IB2008/001331 WO2009095742A1 (en) 2008-01-31 2008-01-31 New i-crei derived single-chain meganuclease and uses thereof
IBPCT/IB2008/001331 2008-01-31
PCT/IB2009/000439 WO2009095793A1 (en) 2008-01-31 2009-02-02 New i-crei derived single-chain meganuclease and uses thereof

Publications (1)

Publication Number Publication Date
CA2729124A1 true CA2729124A1 (en) 2009-08-06

Family

ID=39884323

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2729124A Abandoned CA2729124A1 (en) 2008-01-31 2009-02-02 New i-crei derived single-chain meganuclease and uses thereof

Country Status (7)

Country Link
US (1) US8927247B2 (https=)
EP (1) EP2245147A1 (https=)
JP (1) JP2011514144A (https=)
CN (1) CN101970649B (https=)
AU (1) AU2009208732A1 (https=)
CA (1) CA2729124A1 (https=)
WO (2) WO2009095742A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025101946A1 (en) * 2023-11-08 2025-05-15 Precision Biosciences, Inc. Polypeptide linkers for use in engineered meganucleases

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AU2003215869B2 (en) † 2002-03-15 2008-04-24 Cellectis Hybrid and single chain meganucleases and use thereof
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Cited By (1)

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Also Published As

Publication number Publication date
CN101970649A (zh) 2011-02-09
US8927247B2 (en) 2015-01-06
WO2009095793A1 (en) 2009-08-06
CN101970649B (zh) 2014-02-12
EP2245147A1 (en) 2010-11-03
WO2009095742A1 (en) 2009-08-06
JP2011514144A (ja) 2011-05-06
AU2009208732A1 (en) 2009-08-06
US20110179506A1 (en) 2011-07-21

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