CA2719453A1 - Methods for improving lid margin and tear film function and treatment of lid margin disease using tetracycline family antibiotics - Google Patents

Methods for improving lid margin and tear film function and treatment of lid margin disease using tetracycline family antibiotics Download PDF

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Publication number
CA2719453A1
CA2719453A1 CA2719453A CA2719453A CA2719453A1 CA 2719453 A1 CA2719453 A1 CA 2719453A1 CA 2719453 A CA2719453 A CA 2719453A CA 2719453 A CA2719453 A CA 2719453A CA 2719453 A1 CA2719453 A1 CA 2719453A1
Authority
CA
Canada
Prior art keywords
blepharitis
eyelid
disease
subject
lid margin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2719453A
Other languages
English (en)
French (fr)
Inventor
Eric Donnenfeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2719453A1 publication Critical patent/CA2719453A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2719453A 2008-03-26 2009-03-26 Methods for improving lid margin and tear film function and treatment of lid margin disease using tetracycline family antibiotics Abandoned CA2719453A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7085008P 2008-03-26 2008-03-26
US61/070,850 2008-03-26
PCT/US2009/038428 WO2009120881A1 (en) 2008-03-26 2009-03-26 Methods for improving lid margin and tear film function and treatment of lid margin desease using tetracycline family antibiotics

Publications (1)

Publication Number Publication Date
CA2719453A1 true CA2719453A1 (en) 2009-10-01

Family

ID=40750879

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2719453A Abandoned CA2719453A1 (en) 2008-03-26 2009-03-26 Methods for improving lid margin and tear film function and treatment of lid margin disease using tetracycline family antibiotics

Country Status (6)

Country Link
US (1) US20110059925A1 (enExample)
EP (1) EP2285346A1 (enExample)
JP (1) JP2011515494A (enExample)
AU (1) AU2009228205A1 (enExample)
CA (1) CA2719453A1 (enExample)
WO (1) WO2009120881A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090043365A1 (en) * 2005-07-18 2009-02-12 Kolis Scientific, Inc. Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma
US8950405B2 (en) 2006-05-15 2015-02-10 Tearscience, Inc. Treatment of obstructive disorders of the eye or eyelid
US7981146B2 (en) 2006-05-15 2011-07-19 Tearscience Inc. Inner eyelid treatment for treating meibomian gland dysfunction
US7981095B2 (en) * 2005-07-18 2011-07-19 Tearscience, Inc. Methods for treating meibomian gland dysfunction employing fluid jet
WO2013003594A2 (en) 2011-06-28 2013-01-03 Tearscience, Inc. Methods and systems for treating meibomian gland dysfunction using radio-frequency energy
US7981145B2 (en) 2005-07-18 2011-07-19 Tearscience Inc. Treatment of meibomian glands
US20070060988A1 (en) 2005-07-18 2007-03-15 Grenon Stephen M Melting meibomian gland obstructions
US20080114423A1 (en) 2006-05-15 2008-05-15 Grenon Stephen M Apparatus for inner eyelid treatment of meibomian gland dysfunction
US20070016256A1 (en) * 2005-07-18 2007-01-18 Korb Donald R Method and apparatus for treating gland dysfunction
US8128673B2 (en) 2006-05-15 2012-03-06 Tearscience, Inc. System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
US8007524B2 (en) 2006-05-15 2011-08-30 Tearscience, Inc. Heat treatment and heat loss reduction for treating meibomian gland dysfunction
US8128674B2 (en) 2006-05-15 2012-03-06 Tearscience, Inc. System for outer eyelid heat and pressure treatment for treating meibomian gland dysfunction
US8137390B2 (en) 2006-05-15 2012-03-20 Tearscience, Inc. System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction
US7976573B2 (en) 2006-05-15 2011-07-12 Tearscience, Inc. Inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
US9314369B2 (en) 2006-05-15 2016-04-19 Tearscience, Inc. System for inner eyelid treatment of meibomian gland dysfunction
US7981147B2 (en) 2006-05-15 2011-07-19 Tearscience, Inc. Outer eyelid heat and pressure treatment for treating meibomian gland dysfunction
US20130177599A1 (en) * 2012-01-06 2013-07-11 Insite Vision Incorporated Methods and kits for extending contact lens use
US10842670B2 (en) 2012-08-22 2020-11-24 Johnson & Johnson Vision Care, Inc. Apparatuses and methods for diagnosing and/or treating lipid transport deficiency in ocular tear films, and related components and devices
US9763827B2 (en) 2013-04-30 2017-09-19 Tear Film Innovations, Inc. Systems and methods for the treatment of eye conditions
ES2942724T3 (es) 2013-04-30 2023-06-06 Alcon Inc Sistemas para el tratamiento de enfermedades del ojo
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
EP3199163A4 (en) * 2014-09-23 2018-06-20 Agencia Pública Empresarial Sanitaria Hospital Alto Guadalquivir Composition of doxycycline in liposomes for the prevention, improvement and/or treatment of ocular pathologies
US9463201B2 (en) 2014-10-19 2016-10-11 M.G. Therapeutics Ltd Compositions and methods for the treatment of meibomian gland dysfunction
WO2016159351A1 (ja) * 2015-04-03 2016-10-06 参天製薬株式会社 涙腺ドラッグデリバリーシステム
KR20180090251A (ko) * 2015-09-28 2018-08-10 아주라 오프탈믹스 엘티디 마이봄샘 지질 분비를 증가시키기 위한 티올 및 이황화물 함유 약제
EP3442519A4 (en) 2016-04-14 2019-12-04 Azura Opthalmics Ltd. SELDISULFID COMPOSITIONS FOR USE IN THE TREATMENT OF THE MEIBOM DRESSING DYSFUNCTION
US10974063B2 (en) 2016-06-30 2021-04-13 Alcon Inc. Light therapy for eyelash growth
WO2018054932A1 (en) * 2016-09-22 2018-03-29 Novaliq Gmbh Pharmaceutical compositions for use in the therapy of blepharitis
US20180221407A1 (en) * 2017-02-03 2018-08-09 The Administrators Of The Tulane Educational Fund Ophthalmic compositions for therapeutic and prophylactic uses
KR20250065422A (ko) 2017-12-15 2025-05-12 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
EP3741367A1 (en) * 2019-05-21 2020-11-25 Premark Pharma GmbH Treatment of ocular disease
CN115279458A (zh) 2020-01-10 2022-11-01 阿祖拉眼科有限公司 组合物和敏感性说明
CA3199736A1 (en) 2020-11-23 2022-05-27 Sight Sciences, Inc. Formulations and methods for treating conditions of the eye

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE319456T1 (de) * 1998-05-08 2006-03-15 Univ Miami Verwendung von tetracyclinen zur behandlung von störungen der meibomschen drüsen
US7056893B2 (en) * 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
IT1313610B1 (it) * 1999-08-09 2002-09-09 S I F I Societa Ind Farmaceuti Processo per la preparazione di formulazioni acquose per uso oftalmico
US7069084B2 (en) * 2002-06-14 2006-06-27 Seefit Incorporated Method and apparatus for preventing and treating eyelid problems

Also Published As

Publication number Publication date
US20110059925A1 (en) 2011-03-10
JP2011515494A (ja) 2011-05-19
EP2285346A1 (en) 2011-02-23
AU2009228205A1 (en) 2009-10-01
WO2009120881A1 (en) 2009-10-01

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20150326