CA2713025C - Kappa selective opioid receptor antagonist - Google Patents
Kappa selective opioid receptor antagonist Download PDFInfo
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- CA2713025C CA2713025C CA2713025A CA2713025A CA2713025C CA 2713025 C CA2713025 C CA 2713025C CA 2713025 A CA2713025 A CA 2713025A CA 2713025 A CA2713025 A CA 2713025A CA 2713025 C CA2713025 C CA 2713025C
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- disorder
- ethanol
- pharmaceutically acceptable
- compound
- acceptable salt
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| US3912108P | 2008-03-25 | 2008-03-25 | |
| US61/039,121 | 2008-03-25 | ||
| PCT/US2009/030811 WO2009094260A1 (en) | 2008-01-22 | 2009-01-13 | Kappa selective opioid receptor antagonist |
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| CA2713025A1 CA2713025A1 (en) | 2009-07-30 |
| CA2713025C true CA2713025C (en) | 2012-12-04 |
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| AR070218A1 (es) * | 2008-01-22 | 2010-03-25 | Takeda Pharmaceutical | COMPUESTOS TRICíCLICOS, SUS PROFÁRMACOS, UNA COMPOSICIoN FARMACÉUTICA QUE LOS COMPRENDE Y SU USO EN LA PRODUCCIoN DE UN MEDICAMENTO PARA EL TRATAMIENTO DE ENFERMEDADES MEDIADAS POR EL RECEPTOR CRF. |
| BRPI0907382B8 (pt) * | 2008-01-22 | 2021-05-25 | Lilly Co Eli | antagonista de receptor de opioide seletivo capa, seu uso e composição farmacêutica que o compreende |
| US9345703B2 (en) | 2011-09-15 | 2016-05-24 | University Of Kansas | Kappa opioid receptor effectors and uses thereof |
| US10813925B2 (en) | 2011-09-19 | 2020-10-27 | Carmel—Haifa University Economic Corporation Ltd. | Buprenorphine for the treatment of acute suicidality |
| WO2013086496A2 (en) | 2011-12-09 | 2013-06-13 | Research Triangle Institute | 1-substituted 4-arylpiperazine as kappa opioid receptor antagonists |
| EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US9283196B1 (en) | 2013-01-30 | 2016-03-15 | MediSynergics, LLC | Cycloalkyl-diamines for CNS disorders |
| AU2014268361B2 (en) * | 2013-05-24 | 2018-09-06 | Alkermes Pharma Ireland Limited | Morphan and morphinan analogues, and methods of use |
| US10316021B2 (en) | 2016-11-28 | 2019-06-11 | Pfizer Inc. | Heteroarylphenoxy benzamide kappa opioid ligands |
| SG11201908633SA (en) | 2017-03-17 | 2019-10-30 | Scripps Research Inst | Kappa opioid receptor antagonists and products and methods related thereto |
| JP6480616B1 (ja) | 2018-02-08 | 2019-03-13 | 有限会社 ディオン光学技研 | 照準スコープ |
| US11266627B1 (en) | 2021-05-04 | 2022-03-08 | Janssen Pharmaceuticals, Inc. | Compositions and methods for the treatment of depression |
| CN114195693A (zh) * | 2020-09-17 | 2022-03-18 | 广东东阳光药业有限公司 | 一种酰胺化合物的晶型及其制备方法 |
| CN114591211B (zh) * | 2020-12-04 | 2025-10-21 | 广东东阳光药业股份有限公司 | 一种酰胺化合物的共晶及其制备方法 |
| BR112023023030A2 (pt) | 2021-05-04 | 2024-02-15 | Janssen Pharmaceuticals Inc | Composições e métodos para o tratamento de depressão |
| US12161622B2 (en) | 2021-05-04 | 2024-12-10 | Janssen Pharmaceuticals, Inc. | Compositions and methods for the treatment of depression |
| JP2025503646A (ja) * | 2022-01-10 | 2025-02-04 | ヤンセン ファーマシューティカルズ，インコーポレーテッド | うつ病の治療のための組成物及び方法 |
| MX2024008619A (es) * | 2022-01-10 | 2024-09-25 | Janssen Pharmaceuticals Inc | Composiciones y métodos para el tratamiento de la depresión. |
| IL315411A (en) * | 2022-03-07 | 2024-11-01 | Janssen Pharmaceuticals Inc | Pure forms of crystalline eticarpant |
| KR20240156409A (ko) | 2022-03-07 | 2024-10-29 | 얀센 파마슈티칼즈, 인코포레이티드 | 주요 우울 장애 치료에 사용을 위한 아티카프란트의 다형 형태 |
| US20230277500A1 (en) * | 2022-03-07 | 2023-09-07 | Janssen Pharmaceuticals, Inc. | Compositions comprising aticaprant |
| JP7176142B1 (ja) | 2022-03-09 | 2022-11-21 | 直迪 清瀬 | 各アルコール飲用者において飲用し得るアルコール飲料の種類に対応する飲用量の上限値に関する情報を提供するシステム |
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| US5457208A (en) * | 1993-06-21 | 1995-10-10 | Regents Of The University Of Minnesota | Kappa opioid receptor antagonists |
| KR100451610B1 (ko) * | 1999-05-12 | 2004-10-06 | 에프. 호프만-라 로슈 아게 | 이미다조디아제핀 유도체 |
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| US6974824B2 (en) | 2001-01-08 | 2005-12-13 | Research Triangle Institute | Kappa opioid receptor ligands |
| DE60319812T2 (de) * | 2002-03-28 | 2009-04-23 | Wisys Technology Foundation, Inc., Madison | Angstlösende wirkstoffe mit verminderten beruhigenden und ataktischen nebenwirkungen |
| MXPA05003093A (es) * | 2002-09-19 | 2005-07-13 | Lilly Co Eli | Diaril eteres como antagonistas de receptor opiode. |
| AU2004220113A1 (en) * | 2003-03-07 | 2004-09-23 | Eli Lilly And Company | Opioid receptor antagonists |
| MXPA05009508A (es) | 2003-03-07 | 2005-12-14 | Lilly Co Eli | Derivados de nicotinamida 6-substituida como antagonistas de receptor opioide. |
| BRPI0417156A (pt) * | 2003-12-12 | 2007-03-06 | Lilly Co Eli | composto, composição farmacêutica, e, métodos para bloquear receptor mu, capa, delta ou combinação (heterodìmero) dos mesmos em mamìferos, para tratar e/ou prevenir doenças relacionadas com obesidade e obesidade, para suprimir apetite em um paciente, para efetuar perda de peso em um paciente obeso |
| JP2007516284A (ja) * | 2003-12-22 | 2007-06-21 | イーライ リリー アンド カンパニー | オピオイド受容体拮抗物質 |
| ES2308471T3 (es) * | 2004-03-12 | 2008-12-01 | Eli Lilly And Company | Antagonistas de receptores de opioides. |
| AU2005222640A1 (en) * | 2004-03-12 | 2005-09-29 | The Mclean Hospital Corporation | Salvinorin derivatives and uses thereof |
| CA2558568A1 (en) * | 2004-03-12 | 2005-09-29 | Eli Lilly And Company | Opioid receptor antagonists |
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| EP1751103B1 (en) * | 2004-03-15 | 2009-01-14 | Eli Lilly And Company | 4-(5-(aminomethyl)-indole-1-ylmethyl)-benzamide derivatives and related compounds as opioid receptor antagonists for the treatment of obesity |
| WO2007067714A2 (en) * | 2005-12-08 | 2007-06-14 | The Mclean Hospital Corporation | Treatment of sequelae of psychiatric disorders |
| SI2001456T1 (sl) | 2006-04-04 | 2010-04-30 | Emodys Gmbh | Uporaba zmesi, ki vsebuje antagonist na opioidnem kapa receptorju za zdravljenje disocialnih bolezni |
| WO2008021849A2 (en) | 2006-08-09 | 2008-02-21 | Smithkline Beecham Corporation | Novel compounds as antagonists or inverse agonists at opioid receptors |
| US20100222345A1 (en) | 2006-08-09 | 2010-09-02 | Caroline Jean Diaz | Novel compounds as antagonists or inverse agonists for opioid receptors |
| EP2064199A1 (en) | 2006-09-08 | 2009-06-03 | Pfizer Products Inc. | Diaryl ether derivatives and uses thereof |
| BRPI0907382B8 (pt) * | 2008-01-22 | 2021-05-25 | Lilly Co Eli | antagonista de receptor de opioide seletivo capa, seu uso e composição farmacêutica que o compreende |
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