CA2711217C - Antimicrobial compositions - Google Patents
Antimicrobial compositions Download PDFInfo
- Publication number
- CA2711217C CA2711217C CA2711217A CA2711217A CA2711217C CA 2711217 C CA2711217 C CA 2711217C CA 2711217 A CA2711217 A CA 2711217A CA 2711217 A CA2711217 A CA 2711217A CA 2711217 C CA2711217 C CA 2711217C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- antimicrobial composition
- antimicrobial
- alkyl
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 239000004599 antimicrobial Substances 0.000 claims abstract description 75
- 125000002091 cationic group Chemical group 0.000 claims abstract description 62
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 51
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- 150000005691 triesters Chemical class 0.000 claims abstract description 21
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- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims abstract description 15
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- SMGTYJPMKXNQFY-UHFFFAOYSA-N octenidine dihydrochloride Chemical compound Cl.Cl.C1=CC(=NCCCCCCCC)C=CN1CCCCCCCCCCN1C=CC(=NCCCCCCCC)C=C1 SMGTYJPMKXNQFY-UHFFFAOYSA-N 0.000 claims description 4
- OVYMWJFNQQOJBU-UHFFFAOYSA-N 1-octanoyloxypropan-2-yl octanoate Chemical compound CCCCCCCC(=O)OCC(C)OC(=O)CCCCCCC OVYMWJFNQQOJBU-UHFFFAOYSA-N 0.000 claims description 3
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- RDOFJDLLWVCMRU-UHFFFAOYSA-N Diisobutyl adipate Chemical compound CC(C)COC(=O)CCCCC(=O)OCC(C)C RDOFJDLLWVCMRU-UHFFFAOYSA-N 0.000 claims description 3
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 3
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- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 claims description 3
- OJXOOFXUHZAXLO-UHFFFAOYSA-M magnesium;1-bromo-3-methanidylbenzene;bromide Chemical compound [Mg+2].[Br-].[CH2-]C1=CC=CC(Br)=C1 OJXOOFXUHZAXLO-UHFFFAOYSA-M 0.000 claims description 3
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 claims description 3
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- 241000124008 Mammalia Species 0.000 claims description 2
- 150000004287 bisbiguanides Chemical class 0.000 claims description 2
- 150000003856 quaternary ammonium compounds Chemical class 0.000 claims description 2
- 230000001419 dependent effect Effects 0.000 claims 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 abstract description 42
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- 239000002904 solvent Substances 0.000 abstract description 20
- 239000002537 cosmetic Substances 0.000 abstract description 10
- 150000002194 fatty esters Chemical class 0.000 abstract description 5
- 210000003491 skin Anatomy 0.000 description 80
- 235000019441 ethanol Nutrition 0.000 description 68
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 37
- 238000009472 formulation Methods 0.000 description 32
- 150000001875 compounds Chemical class 0.000 description 25
- 239000000243 solution Substances 0.000 description 25
- 235000011187 glycerol Nutrition 0.000 description 21
- 125000004432 carbon atom Chemical group C* 0.000 description 19
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- 230000002421 anti-septic effect Effects 0.000 description 15
- 230000000694 effects Effects 0.000 description 15
- 235000014113 dietary fatty acids Nutrition 0.000 description 14
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- 229930195729 fatty acid Natural products 0.000 description 14
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- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 12
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 11
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- 230000000052 comparative effect Effects 0.000 description 9
- 238000010790 dilution Methods 0.000 description 9
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- 238000001035 drying Methods 0.000 description 8
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 7
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Classifications
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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| IN2014CN03706A (https=) | 2011-11-16 | 2015-10-09 | 3M Innovative Properties Co | |
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| CA2883373A1 (en) * | 2012-08-28 | 2014-03-06 | 3M Innovative Properties Company | Chlorhexidine gluconate compositions, resin systems and articles |
| WO2014124232A2 (en) | 2013-02-07 | 2014-08-14 | Avery Dennison Corporation | Antimicrobial adhesives having improved properties |
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| US9999633B2 (en) | 2013-04-09 | 2018-06-19 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
| US9357772B2 (en) * | 2013-04-09 | 2016-06-07 | International Business Machines Corporation | Antimicrobial cationic polycarbonates |
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| GB201405660D0 (en) * | 2014-03-28 | 2014-05-14 | Gama Healthcare Ltd | A liquid disinfecting composition |
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| JP2022547755A (ja) * | 2020-08-14 | 2022-11-16 | ビーエルアンドエイチ カンパニー，リミテッド | 白癬を防止又は処置するための医薬組成物 |
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- 2008-12-31 EP EP13167054.9A patent/EP2625957A1/en not_active Withdrawn
- 2008-12-31 CN CN2008801269272A patent/CN101951779A/zh active Pending
- 2008-12-31 EP EP08869762.8A patent/EP2240031B1/en not_active Not-in-force
- 2008-12-31 AU AU2008347253A patent/AU2008347253B2/en not_active Ceased
- 2008-12-31 CA CA2711217A patent/CA2711217C/en not_active Expired - Fee Related
- 2008-12-31 BR BRPI0819567 patent/BRPI0819567A2/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101951779A (zh) | 2011-01-19 |
| EP2240031B1 (en) | 2013-09-18 |
| AU2008347253A1 (en) | 2009-07-16 |
| BRPI0819567A2 (pt) | 2015-05-05 |
| EP2240031A2 (en) | 2010-10-20 |
| US8623935B2 (en) | 2014-01-07 |
| EP2625957A1 (en) | 2013-08-14 |
| JP2011507978A (ja) | 2011-03-10 |
| AU2008347253B2 (en) | 2012-04-19 |
| WO2009088894A3 (en) | 2010-07-29 |
| CA2711217A1 (en) | 2009-07-16 |
| WO2009088894A2 (en) | 2009-07-16 |
| CN107019686A (zh) | 2017-08-08 |
| US20100282409A1 (en) | 2010-11-11 |
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| EEER | Examination request |
Effective date: 20131230 |
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| MKLA | Lapsed |
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| MKLA | Lapsed |
Effective date: 20191231 |