CA2708156C - Reagents and methods for detecting analytes - Google Patents
Reagents and methods for detecting analytes Download PDFInfo
- Publication number
- CA2708156C CA2708156C CA2708156A CA2708156A CA2708156C CA 2708156 C CA2708156 C CA 2708156C CA 2708156 A CA2708156 A CA 2708156A CA 2708156 A CA2708156 A CA 2708156A CA 2708156 C CA2708156 C CA 2708156C
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- CA
- Canada
- Prior art keywords
- reagent
- mediator
- glucose
- less
- buffer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- QJIRSSCQIXYYBV-UHFFFAOYSA-N methyl 4-(phenothiazin-3-ylideneamino)benzoate Chemical compound C1=CC(C(=O)OC)=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 QJIRSSCQIXYYBV-UHFFFAOYSA-N 0.000 description 1
- ZVRFBOCINRAXEV-UHFFFAOYSA-N methyl 4-[(7-acetylphenothiazin-3-ylidene)amino]benzoate Chemical compound C1=CC(C(=O)OC)=CC=C1N=C1C=C2SC3=CC(C(C)=O)=CC=C3N=C2C=C1 ZVRFBOCINRAXEV-UHFFFAOYSA-N 0.000 description 1
- ZMJFEJMPTUDZBH-UHFFFAOYSA-N n,n-diethyl-4-(phenothiazin-3-ylideneamino)aniline Chemical compound C1=CC(N(CC)CC)=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 ZMJFEJMPTUDZBH-UHFFFAOYSA-N 0.000 description 1
- OMVNPYJPBBNXEO-UHFFFAOYSA-N n-(4-chlorophenyl)phenothiazin-3-imine Chemical compound C1=CC(Cl)=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 OMVNPYJPBBNXEO-UHFFFAOYSA-N 0.000 description 1
- GBHXUDVHFRNSDE-UHFFFAOYSA-N n-(4-ethylphenyl)-7-(4-ethylphenyl)iminophenothiazin-4-amine Chemical compound C1=CC(CC)=CC=C1NC1=CC=CC(N=C2C=C3)=C1SC2=CC3=NC1=CC=C(CC)C=C1 GBHXUDVHFRNSDE-UHFFFAOYSA-N 0.000 description 1
- KHAPWYDGYZRRII-UHFFFAOYSA-N n-(4-ethylphenyl)phenothiazin-3-imine Chemical compound C1=CC(CC)=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 KHAPWYDGYZRRII-UHFFFAOYSA-N 0.000 description 1
- VVQCSQXNNJGRAS-UHFFFAOYSA-N n-(4-methoxyphenyl)phenothiazin-3-imine Chemical compound C1=CC(OC)=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 VVQCSQXNNJGRAS-UHFFFAOYSA-N 0.000 description 1
- WJPLSLZLPGUUGJ-UHFFFAOYSA-N n-[4-(trifluoromethyl)phenyl]phenothiazin-3-imine Chemical compound C1=CC(C(F)(F)F)=CC=C1N=C1C=C2SC3=CC=CC=C3N=C2C=C1 WJPLSLZLPGUUGJ-UHFFFAOYSA-N 0.000 description 1
- 239000006174 pH buffer Substances 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 239000011112 polyethylene naphthalate Substances 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- MMXZSJMASHPLLR-UHFFFAOYSA-N pyrroloquinoline quinone Chemical compound C12=C(C(O)=O)C=C(C(O)=O)N=C2C(=O)C(=O)C2=C1NC(C(=O)O)=C2 MMXZSJMASHPLLR-UHFFFAOYSA-N 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000006479 redox reaction Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940048109 sodium methyl cocoyl taurate Drugs 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 229940116269 uric acid Drugs 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/004—Enzyme electrodes mediator-assisted
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Electrochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US712607P | 2007-12-10 | 2007-12-10 | |
| US61/007,126 | 2007-12-10 | ||
| PCT/US2008/086214 WO2009076433A1 (en) | 2007-12-10 | 2008-12-10 | Reagents and methods for detecting analytes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2708156A1 CA2708156A1 (en) | 2009-06-18 |
| CA2708156C true CA2708156C (en) | 2018-01-23 |
Family
ID=40329165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2708156A Expired - Fee Related CA2708156C (en) | 2007-12-10 | 2008-12-10 | Reagents and methods for detecting analytes |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20090145775A1 (enExample) |
| EP (1) | EP2222866A1 (enExample) |
| JP (2) | JP5856371B2 (enExample) |
| CN (1) | CN101896618B (enExample) |
| BR (1) | BRPI0820721A2 (enExample) |
| CA (1) | CA2708156C (enExample) |
| RU (2) | RU2518310C2 (enExample) |
| WO (1) | WO2009076433A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| IT1191646B (it) | 1985-12-19 | 1988-03-23 | Montedison Spa | Processo per l'adesione di poli-p.xililene a substrati e articoli ottenuti |
| JP5395665B2 (ja) | 2006-09-22 | 2014-01-22 | バイエル・ヘルスケア・エルエルシー | 改善された安定性およびヘマトクリット性能（ｐｅｒｆｏｒｍａｎｃｅ）を有するバイオセンサー系 |
| RU2524660C2 (ru) * | 2007-12-10 | 2014-07-27 | БАЙЕР ХЕЛТКЭА ЭлЭлСи | Способ получения медиатора 3-фенилимино-3н-фенотиазина или 3-фенилимино-3н-феноксазина |
| JP5773883B2 (ja) | 2008-12-08 | 2015-09-02 | バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ | バイオセンサのための低全塩試薬組成物およびシステム |
| EP4252639A3 (en) * | 2009-02-26 | 2024-01-03 | Abbott Diabetes Care Inc. | Method of calibrating an analyte sensor |
| EP4309580A3 (en) | 2009-07-23 | 2024-02-28 | Abbott Diabetes Care Inc. | Continuous analyte measurement system |
| TWI565943B (zh) * | 2011-07-22 | 2017-01-11 | 拜耳保健公司 | 具有增進測量性能之生物感測器乾燥劑系統 |
| KR101847758B1 (ko) | 2014-01-24 | 2018-04-10 | 에프. 호프만-라 로슈 아게 | 유니- 및 노-코드 테스트 스트라이프 제조 방법 |
| JP7333160B2 (ja) | 2017-09-28 | 2023-08-24 | 大日本印刷株式会社 | 高摺動性樹脂成形体 |
| CN107941880B (zh) * | 2017-11-16 | 2020-07-31 | 江苏鱼跃医疗设备股份有限公司 | 用于提高葡萄糖传感器储存稳定性的包含甜菜碱衍生物的反应试剂以及葡萄糖传感器 |
| CA3152919A1 (en) | 2019-09-30 | 2021-04-08 | Stanley Zhen-Jin TEO | Electrochemical sensor for analysis of beverages |
| MX2023008608A (es) * | 2021-01-25 | 2023-08-04 | Trividia Health Inc | Biosensor para la determinacion de hemoglobina. |
| CN118772197A (zh) * | 2024-06-07 | 2024-10-15 | 江苏鱼跃凯立特生物科技有限公司 | 一种苯胺2，4二磷酸及制备方法和制备二磷酸苯胺吩噻嗪的方法与应用 |
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-
2008
- 2008-12-10 EP EP08859272A patent/EP2222866A1/en not_active Withdrawn
- 2008-12-10 JP JP2010538123A patent/JP5856371B2/ja active Active
- 2008-12-10 US US12/316,142 patent/US20090145775A1/en not_active Abandoned
- 2008-12-10 WO PCT/US2008/086214 patent/WO2009076433A1/en not_active Ceased
- 2008-12-10 RU RU2010128611/15A patent/RU2518310C2/ru not_active IP Right Cessation
- 2008-12-10 BR BRPI0820721-6A patent/BRPI0820721A2/pt not_active IP Right Cessation
- 2008-12-10 CN CN200880120025.8A patent/CN101896618B/zh active Active
- 2008-12-10 CA CA2708156A patent/CA2708156C/en not_active Expired - Fee Related
-
2014
- 2014-01-16 RU RU2014101344/15A patent/RU2014101344A/ru not_active Application Discontinuation
-
2015
- 2015-08-19 JP JP2015161610A patent/JP6251217B2/ja active Active
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2017
- 2017-08-21 US US15/682,182 patent/US10696998B2/en active Active
-
2020
- 2020-05-13 US US15/931,185 patent/US11180790B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN101896618A (zh) | 2010-11-24 |
| WO2009076433A1 (en) | 2009-06-18 |
| JP2016006432A (ja) | 2016-01-14 |
| BRPI0820721A2 (pt) | 2015-06-16 |
| CA2708156A1 (en) | 2009-06-18 |
| JP2011505834A (ja) | 2011-03-03 |
| RU2518310C2 (ru) | 2014-06-10 |
| RU2014101344A (ru) | 2015-07-27 |
| US10696998B2 (en) | 2020-06-30 |
| JP5856371B2 (ja) | 2016-02-09 |
| JP6251217B2 (ja) | 2017-12-20 |
| US11180790B2 (en) | 2021-11-23 |
| US20200270668A1 (en) | 2020-08-27 |
| US20170349929A1 (en) | 2017-12-07 |
| CN101896618B (zh) | 2015-04-22 |
| HK1147525A1 (en) | 2011-08-12 |
| RU2010128611A (ru) | 2012-01-20 |
| US20090145775A1 (en) | 2009-06-11 |
| EP2222866A1 (en) | 2010-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20211210 |