CA2704422C - Compositions and methods of enhancing immune responses to eimeria - Google Patents

Compositions and methods of enhancing immune responses to eimeria Download PDF

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Publication number
CA2704422C
CA2704422C CA2704422A CA2704422A CA2704422C CA 2704422 C CA2704422 C CA 2704422C CA 2704422 A CA2704422 A CA 2704422A CA 2704422 A CA2704422 A CA 2704422A CA 2704422 C CA2704422 C CA 2704422C
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CA
Canada
Prior art keywords
vaccine
seq
polypeptide
subject
trap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2704422A
Other languages
English (en)
French (fr)
Other versions
CA2704422A1 (en
Inventor
Walter Bottje
Billy Hargis
Luc Berghman
Young Min Kwon
Kimberly Cole
Mandy Cox
Sherryll Layton
Said El-Ashram
John Barta
Guillermo Tellez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Guelph
Texas A&M University
University of Arkansas at Little Rock
Original Assignee
University of Guelph
Texas A&M University
University of Arkansas at Little Rock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Guelph, Texas A&M University, University of Arkansas at Little Rock filed Critical University of Guelph
Priority to CA3051748A priority Critical patent/CA3051748C/en
Publication of CA2704422A1 publication Critical patent/CA2704422A1/en
Application granted granted Critical
Publication of CA2704422C publication Critical patent/CA2704422C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA2704422A 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria Active CA2704422C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3051748A CA3051748C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98461207P 2007-11-01 2007-11-01
US60/984,612 2007-11-01
PCT/US2008/082254 WO2009059298A2 (en) 2007-11-01 2008-11-03 Compositions and methods of enhancinc immune responses to eimeria

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3051748A Division CA3051748C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria

Publications (2)

Publication Number Publication Date
CA2704422A1 CA2704422A1 (en) 2009-05-07
CA2704422C true CA2704422C (en) 2019-09-24

Family

ID=40591796

Family Applications (3)

Application Number Title Priority Date Filing Date
CA2704422A Active CA2704422C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria
CA3156538A Active CA3156538C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria
CA3051748A Active CA3051748C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA3156538A Active CA3156538C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria
CA3051748A Active CA3051748C (en) 2007-11-01 2008-11-03 Compositions and methods of enhancing immune responses to eimeria

Country Status (14)

Country Link
US (3) US8956849B2 (enExample)
EP (2) EP2214701B1 (enExample)
JP (1) JP5480812B2 (enExample)
CN (2) CN103893747B (enExample)
AU (1) AU2008318357B2 (enExample)
BR (1) BRPI0819229B1 (enExample)
CA (3) CA2704422C (enExample)
DK (2) DK2214701T3 (enExample)
ES (2) ES2761693T3 (enExample)
HU (2) HUE047164T2 (enExample)
NZ (2) NZ601880A (enExample)
PL (2) PL3097926T3 (enExample)
PT (2) PT2214701T (enExample)
WO (1) WO2009059298A2 (enExample)

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WO2011156619A2 (en) * 2010-06-09 2011-12-15 The Board Of Trustees Of The University Of Arkansas Vaccine and methods to reduce campylobacter infection
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JP6530742B2 (ja) 2013-03-15 2019-06-12 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー 腸内病原体の免疫応答を強化する組成物及び方法
CN114621942B (zh) 2015-05-08 2024-05-14 诺维信公司 α-淀粉酶变体以及编码其的多核苷酸
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
BR112018072592A2 (pt) 2016-05-03 2019-04-16 The Board Of Trustees Of The University Of Arkansas vetor de vacina de levedura que inclui polipeptídeos imunoestimulantes e antigênicos, e métodos de uso dos mesmos
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN110468069B (zh) * 2019-08-19 2020-11-06 中国水产科学研究院长江水产研究所 一种干酪乳杆菌yfi-5及其在抗鲤疱疹病毒ii型中的应用
CN113304254A (zh) * 2021-06-07 2021-08-27 吉林大学 一种微小隐孢子虫Cp15重组侵入型乳酸菌活载体疫苗

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Also Published As

Publication number Publication date
WO2009059298A2 (en) 2009-05-07
NZ601880A (en) 2013-12-20
US20110111015A1 (en) 2011-05-12
BRPI0819229B1 (pt) 2019-01-22
PT3097926T (pt) 2020-01-08
WO2009059298A8 (en) 2010-08-05
JP2011503003A (ja) 2011-01-27
ES2761693T3 (es) 2020-05-20
NZ585777A (en) 2012-09-28
AU2008318357A1 (en) 2009-05-07
ES2599905T3 (es) 2017-02-06
PL2214701T3 (pl) 2017-01-31
CN101969990A (zh) 2011-02-09
EP3097926B1 (en) 2019-10-02
EP2214701A4 (en) 2011-06-01
EP3097926A1 (en) 2016-11-30
US8956849B2 (en) 2015-02-17
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