HUE047164T2 - Kompozíciók és eljárások eimeria elleni immunválasz fokozására - Google Patents

Kompozíciók és eljárások eimeria elleni immunválasz fokozására

Info

Publication number
HUE047164T2
HUE047164T2 HUE16175274A HUE16175274A HUE047164T2 HU E047164 T2 HUE047164 T2 HU E047164T2 HU E16175274 A HUE16175274 A HU E16175274A HU E16175274 A HUE16175274 A HU E16175274A HU E047164 T2 HUE047164 T2 HU E047164T2
Authority
HU
Hungary
Prior art keywords
eimeria
compositions
methods
immune responses
enhancing immune
Prior art date
Application number
HUE16175274A
Other languages
English (en)
Inventor
Walter Bottje
Billy Hargis
Luc Berghman
Young Kwon
Kimberly Cole
Mandy Cox
Sherryll Layton
Saeed El-Ashram
John Barta
Guillermo Tellez
Original Assignee
Univ Arkansas
Texas A & M Univ Sys
Univ Guelph
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arkansas, Texas A & M Univ Sys, Univ Guelph filed Critical Univ Arkansas
Publication of HUE047164T2 publication Critical patent/HUE047164T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HUE16175274A 2007-11-01 2008-11-03 Kompozíciók és eljárások eimeria elleni immunválasz fokozására HUE047164T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98461207P 2007-11-01 2007-11-01

Publications (1)

Publication Number Publication Date
HUE047164T2 true HUE047164T2 (hu) 2020-04-28

Family

ID=40591796

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE16175274A HUE047164T2 (hu) 2007-11-01 2008-11-03 Kompozíciók és eljárások eimeria elleni immunválasz fokozására
HUE08843740A HUE030655T2 (hu) 2007-11-01 2008-11-03 Készítmények és eljárások eimeria elleni immunválasz fokozására

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE08843740A HUE030655T2 (hu) 2007-11-01 2008-11-03 Készítmények és eljárások eimeria elleni immunválasz fokozására

Country Status (15)

Country Link
US (3) US8956849B2 (hu)
EP (2) EP3097926B1 (hu)
JP (1) JP5480812B2 (hu)
CN (2) CN103893747B (hu)
AU (1) AU2008318357B2 (hu)
BR (1) BRPI0819229B1 (hu)
CA (3) CA3156538C (hu)
DK (2) DK2214701T3 (hu)
ES (2) ES2761693T3 (hu)
HK (1) HK1146575A1 (hu)
HU (2) HUE047164T2 (hu)
NZ (2) NZ601880A (hu)
PL (2) PL2214701T3 (hu)
PT (2) PT2214701T (hu)
WO (1) WO2009059298A2 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2066339T3 (da) * 2006-09-18 2014-11-03 Univ Arkansas Sammensætninger og fremgangsmåder til forstærkning af immunreaktioner
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
CN102037135A (zh) 2007-10-30 2011-04-27 阿肯色大学评议会 增强对有鞭毛的细菌的免疫反应的组合物和方法
CA3156538C (en) * 2007-11-01 2023-12-12 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to eimeria
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
ES2643646T3 (es) 2010-01-21 2017-11-23 The Board Of Trustees Of The University Of Arkansas Vectores de vacuna y métodos para potenciar las respuestas inmunitarias
EP2579901B1 (en) * 2010-06-09 2019-08-07 The Board of Trustees of The University of Arkansas Vaccine and methods to reduce campylobacter infection
AU2013203641B2 (en) * 2011-04-13 2014-08-21 Epizyme, Inc. Aryl-or heteroaryl-substituted benzene compounds
WO2013123412A1 (en) * 2012-02-17 2013-08-22 Children's Medical Center Corporation Conformation-stabilized trap antigens
NZ711019A (en) * 2013-02-14 2019-07-26 Univ Arkansas Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection
BR112015023024B1 (pt) 2013-03-15 2022-04-19 The Board Of Trustees Of The University Of Arkansas Vetor de vacina e composições farmacêuticas compreendendo o mesmo
CN114621942B (zh) 2015-05-08 2024-05-14 诺维信公司 α-淀粉酶变体以及编码其的多核苷酸
WO2017192671A1 (en) 2016-05-03 2017-11-09 The Board Of Trustees Of The University Of Arkansas Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN110468069B (zh) * 2019-08-19 2020-11-06 中国水产科学研究院长江水产研究所 一种干酪乳杆菌yfi-5及其在抗鲤疱疹病毒ii型中的应用
CN113304254A (zh) * 2021-06-07 2021-08-27 吉林大学 一种微小隐孢子虫Cp15重组侵入型乳酸菌活载体疫苗

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL170938B1 (pl) * 1991-03-05 1997-02-28 Wellcome Found Sposób wytwarzania szczepionki przeciwko infekcjom Salmonella PL PL
US7405270B2 (en) 1991-10-25 2008-07-29 Immunex Corporation CD40-Ligand lacking native-pattern glycosylation
US5961974A (en) * 1991-10-25 1999-10-05 Immunex Corporation Monoclonal antibodies to CD40 ligand, pharmaceutical composition comprising the same and hybridomas producing the same
US5962406A (en) * 1991-10-25 1999-10-05 Immunex Corporation Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same
US5981724A (en) * 1991-10-25 1999-11-09 Immunex Corporation DNA encoding CD40 ligand, a cytokine that binds CD40
US5716805A (en) * 1991-10-25 1998-02-10 Immunex Corporation Methods of preparing soluble, oligomeric proteins
DK0667901T4 (da) 1991-10-25 2008-11-10 Immunex Corp Hidtil ukendt cytokin
EP0659086B1 (en) * 1992-09-04 1998-11-11 The University of Saskatchewan Novel bacterial vaccines using vaccine strains of pathogenic bacteria
US5540926A (en) * 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
US5565321A (en) * 1993-01-22 1996-10-15 Immunex Corporation Detection of mutations in a CD40 ligand gene
AU1059095A (en) 1993-11-24 1995-06-13 Australian National University, The Treatment of viral disease with cd40l peptide
MX9605088A (es) * 1994-04-28 1997-08-30 Boehringer Ingelheim Pharma Metodos para proliferar y diferenciar celulas b y sus usos.
PT812206E (pt) 1995-03-01 2002-11-29 Immunex Corp Proteina de ligacao a cd40 para estimulacao de uma resposta imunitaria
PT832229E (pt) 1995-06-07 2004-06-30 Immunex Corp Muteina de cd40l
US6713279B1 (en) * 1995-12-07 2004-03-30 Diversa Corporation Non-stochastic generation of genetic vaccines and enzymes
US6479258B1 (en) * 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US6306387B1 (en) * 1997-05-29 2001-10-23 The Research Foundation Of State University Of New York Antigen delivery system
US20030045492A1 (en) 1997-08-13 2003-03-06 Tang De-Chu C. Vaccination by topical application of recombinant vectors
US6969609B1 (en) * 1998-12-09 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Serivces Recombinant vector expressing multiple costimulatory molecules and uses thereof
CA2223225A1 (en) 1997-11-28 1999-05-28 Canadian Red Cross Society Method for inhibiting in vivo immune response
CA2313805A1 (en) 1997-12-19 1999-07-01 Immunex Corporation Method for reducing susceptibility to hiv infection
GB9806449D0 (en) * 1998-03-25 1998-05-27 Peptide Therapeutics Ltd Attenuated bacteria useful in vaccines
US6190669B1 (en) * 1998-05-13 2001-02-20 University Of Maryland, Baltimore Attenuated mutants of salmonella which constitutively express the Vi antigen
DK1108034T3 (da) * 1998-09-04 2008-11-10 Emergent Product Dev Uk Ltd Svækkede salmonella SPI2-mutanter som antigenbærere
US7300774B1 (en) * 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
EP1067194A1 (en) 1999-04-16 2001-01-10 F. Hoffmann-La Roche Ag Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof
AR023482A1 (es) 1999-04-16 2002-09-04 Hoffmann La Roche Acidos nucleicos que codifican polipeptidos quimericos cd40/cd4ol, metodos para su produccion y usos de los mismos
US7803765B2 (en) * 1999-05-05 2010-09-28 Phylogica Limited Methods of constructing biodiverse gene fragment libraries and biological modulators isolated therefrom
AU1084901A (en) * 1999-10-14 2001-04-23 Martha S. Hayden-Ledbetter Dna vaccines encoding antigen linked to a domain that binds cd40
ATE269104T1 (de) * 1999-12-28 2004-07-15 Akzo Nobel Nv Salmonella impfstoff, der keinen antikörper gegen flagellin oder gegen flagella induziert
ATE412427T1 (de) 2000-02-02 2008-11-15 Us Health Cd40-ligand als adjuvant für respiratorisches syncytialvirus-impfstoff
CA2402252A1 (en) * 2000-03-17 2001-09-27 Pharmacia & Upjohn Company Salmonella vaccine materials and methods
GB0015426D0 (en) * 2000-06-24 2000-08-16 Univ Southampton Method for generating soluble highly multimeric proteins
AU2001273009A1 (en) 2000-06-26 2002-01-08 Maxygen, Inc. Methods and compositions for developing spore display systems for medicinal and industrial applications
AU2002221780A1 (en) 2000-10-31 2002-05-15 F.Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
US6855493B2 (en) * 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
WO2002092773A2 (en) 2001-05-15 2002-11-21 Ortho-Mcneil Pharmaceutical, Inc. Ex-vivo priming for generating cytotoxic t lymphocytes specific for non-tumor antigens to treat autoimmune and allergic disease
BR0210850A (pt) * 2001-07-06 2004-12-07 Biolog Lab Teva Ltd ácidos nucléicos que codificam um antìgeno de 250 kda recombinante de esporozoìtos/merozoìtos de eimeria máxima e seus usos
ZA200400479B (en) * 2001-07-06 2006-05-31 Abic Biolog Lab Teva Nucleic acids encoding recombinant 56 a 82 KDA antigens from gametocytes of Eimeria maxima and their use
ITMI20011986A1 (it) 2001-09-25 2003-03-25 San Raffaele Centro Fond Metodo e composizione per l'attivazione di cellule presentanti l'antigene
US7378089B2 (en) 2001-10-02 2008-05-27 The Board Of Trustees Of The Leland Stanford Junior University Gene therapy for the prevention of autoimmune disease
US7238499B2 (en) * 2001-12-21 2007-07-03 Immunex Corporation Trimeric macrophage scavenger receptor fusion proteins and encoding nucleic acids
EP1487273B1 (en) * 2002-02-13 2009-01-21 Immunology Laboratories, Inc. Compositions and methods for treatment of microbial infections
US6923958B2 (en) * 2002-03-02 2005-08-02 The Scripps Research Institute DNA vaccines encoding CEA and a CD40 ligand and methods of use thereof
US8133493B2 (en) * 2002-04-15 2012-03-13 Washington University Regulated attenuation of live vaccines to enhance cross-protective immunogenicity
US7495090B2 (en) * 2002-05-23 2009-02-24 The Regents Of The University Of California Nucleic acids encoding chimeric CD154 polypeptides
US20050181994A1 (en) * 2003-01-06 2005-08-18 Xencor, Inc. Novel variants of CD40L protein
US20060014248A1 (en) * 2003-01-06 2006-01-19 Xencor, Inc. TNF super family members with altered immunogenicity
US7754209B2 (en) * 2003-07-26 2010-07-13 Trubion Pharmaceuticals Binding constructs and methods for use thereof
WO2005035570A2 (en) 2003-10-10 2005-04-21 Xencor, Inc. Variants of cd40l protein
EP1720905A2 (en) 2003-12-11 2006-11-15 Sidney Kimmel Cancer Center Methods for generating immunity to antigen
US8828957B2 (en) * 2003-12-11 2014-09-09 Microvax, Llc Methods for generating immunity to antigen
WO2005113598A2 (en) 2004-05-21 2005-12-01 Xencor, Inc. Tnf super family members with altered immunogenicity
US8513008B2 (en) 2004-10-07 2013-08-20 Argos Therapeutics, Inc. Mature dendritic cell compositions and methods for culturing same
AU2005294150B2 (en) * 2004-10-07 2011-06-16 Coimmune, Inc. Mature dendritic cell compositions and methods for culturing same
WO2006105972A1 (en) 2005-04-07 2006-10-12 Universite Libre De Bruxelles Transgenic organism expressing cd40l and uses thereof
US20060286074A1 (en) * 2005-05-31 2006-12-21 Yucheng Tang Methods for immunotherapy of cancer
PT1949913E (pt) 2005-10-07 2010-08-24 Proyecto Biomedicina Cima Sl Associação imunoestimuladora para a profilaxia e o tratamento da hepatite c
US9533036B2 (en) * 2005-11-07 2017-01-03 Microvax, Llc Methods for generating immune responses to influenza antigens with a secretable CD40L fusion protein
DE102005054643B3 (de) 2005-11-10 2007-02-15 Assa Abloy Sicherheitstechnik Gmbh Schließzylinder
WO2007054658A1 (en) 2005-11-14 2007-05-18 King's College London Control of immune responses
CU23576A1 (es) * 2006-02-28 2010-09-30 Ct Ingenieria Genetica Biotech Antígenos vacunales quiméricos contra el virus de la influenza aviar
WO2007103048A2 (en) * 2006-03-01 2007-09-13 Regents Of The University Of Colorado Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity
WO2007106073A2 (en) * 2006-03-02 2007-09-20 University Of Massachusetts Modified pathogens for use as vaccines
FR2898905B1 (fr) * 2006-03-24 2008-05-09 Rhodia Recherches & Tech Composition polyisocyanate a proprietes anti-chocs ameliorees
US20090246220A1 (en) * 2006-08-28 2009-10-01 Ertl Hildegund C J Constructs for enhancing immune responses
DK2066339T3 (da) * 2006-09-18 2014-11-03 Univ Arkansas Sammensætninger og fremgangsmåder til forstærkning af immunreaktioner
WO2008109825A2 (en) 2007-03-08 2008-09-12 Mayo Foundation For Medical Education And Research Inducing immune-mediated tumor cell death
CN101024076B (zh) * 2007-03-29 2010-08-18 中国农业大学 球虫的新用途
EP3072903B1 (en) * 2007-07-10 2017-10-25 Apogenix AG Tnf superfamily collectin fusion proteins
CN102037135A (zh) * 2007-10-30 2011-04-27 阿肯色大学评议会 增强对有鞭毛的细菌的免疫反应的组合物和方法
CA3156538C (en) * 2007-11-01 2023-12-12 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to eimeria
PT2310509E (pt) * 2008-07-21 2015-05-19 Apogenix Gmbh Moléculas de tnfsf em cadeia simples
US8316310B2 (en) 2008-08-05 2012-11-20 International Business Machines Corporation System and method for human identification proof for use in virtual environments
EP2184229B1 (en) * 2008-11-11 2012-10-17 AGUSTAWESTLAND S.p.A. Helicopter rotor
US20100150958A1 (en) * 2008-12-15 2010-06-17 Vectogen Pty Ltd. Methods and Compositions for Use of a Coccidiosis Vaccine
ES2643646T3 (es) * 2010-01-21 2017-11-23 The Board Of Trustees Of The University Of Arkansas Vectores de vacuna y métodos para potenciar las respuestas inmunitarias
AU2012323316B2 (en) * 2011-10-11 2017-08-10 Viela Bio, Inc. CD40L-specific Tn3-derived scaffolds and methods of use thereof
US20140079704A1 (en) * 2012-09-11 2014-03-20 The Texas A&M University System BI-Specific Diabodies For Masking And Targeting Vaccines
CN104884069B (zh) * 2012-10-29 2018-11-27 阿肯色大学评议会 新的黏膜佐剂和递送系统
NZ711019A (en) * 2013-02-14 2019-07-26 Univ Arkansas Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection
BR112015023024B1 (pt) * 2013-03-15 2022-04-19 The Board Of Trustees Of The University Of Arkansas Vetor de vacina e composições farmacêuticas compreendendo o mesmo
KR20170007853A (ko) * 2014-06-05 2017-01-20 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 항체 가이드된 백신 및 신속한 성숙 면역 반응을 생성하기 위한 사용 방법
WO2016054225A1 (en) * 2014-09-30 2016-04-07 Stc.Unm Plasmid delivery in the treatment of cancer and other disease states
JP7208010B2 (ja) * 2016-03-29 2023-01-18 ユニバーシティ オブ サザン カリフォルニア 癌を標的とするキメラ抗原受容体
HUE056670T2 (hu) * 2016-05-27 2022-02-28 Abbvie Biotherapeutics Inc Anti-CD40 antitestek és alkalmazásaik
CA3033788A1 (en) * 2016-08-17 2018-02-22 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof

Also Published As

Publication number Publication date
AU2008318357A1 (en) 2009-05-07
CN103893747B (zh) 2016-01-06
BRPI0819229B1 (pt) 2019-01-22
EP2214701A4 (en) 2011-06-01
US10842858B2 (en) 2020-11-24
NZ601880A (en) 2013-12-20
NZ585777A (en) 2012-09-28
CN103893747A (zh) 2014-07-02
US20110111015A1 (en) 2011-05-12
ES2761693T3 (es) 2020-05-20
JP2011503003A (ja) 2011-01-27
DK3097926T3 (da) 2019-12-16
EP2214701A2 (en) 2010-08-11
US20180333474A1 (en) 2018-11-22
EP3097926B1 (en) 2019-10-02
AU2008318357A2 (en) 2010-06-24
HUE030655T2 (hu) 2017-05-29
CA2704422C (en) 2019-09-24
WO2009059298A2 (en) 2009-05-07
WO2009059298A8 (en) 2010-08-05
AU2008318357B2 (en) 2015-01-22
HK1146575A1 (zh) 2011-06-24
CN101969990B (zh) 2014-07-09
US10016493B2 (en) 2018-07-10
US8956849B2 (en) 2015-02-17
PL2214701T3 (pl) 2017-01-31
CA3051748C (en) 2022-07-12
PT3097926T (pt) 2020-01-08
PT2214701T (pt) 2016-11-02
CA3156538A1 (en) 2009-05-07
US20150216954A1 (en) 2015-08-06
WO2009059298A3 (en) 2009-09-24
EP2214701B1 (en) 2016-08-03
EP3097926A1 (en) 2016-11-30
JP5480812B2 (ja) 2014-04-23
PL3097926T3 (pl) 2020-04-30
BRPI0819229A2 (pt) 2015-05-05
CA3051748A1 (en) 2009-05-07
CA2704422A1 (en) 2009-05-07
ES2599905T3 (es) 2017-02-06
DK2214701T3 (en) 2016-12-12
CN101969990A (zh) 2011-02-09
CA3156538C (en) 2023-12-12

Similar Documents

Publication Publication Date Title
HK1146575A1 (zh) 提高針對艾美球蟲的免疫反應的成分和方法
HRP20181343T1 (hr) Postupci i pripravci za induciranje imunosnog odgovora na egfrviii
PL2066339T3 (pl) Kompozycje i sposoby zwiększania odpowiedzi immunologicznych
EP2111231A4 (en) METHODS AND COMPOSITIONS FOR IMPROVING IMMUNE RESPONSES
HK1146644A1 (en) Compositions and methods of enhancing immune responses to flagellated bacterium
EP2334185A4 (en) COMPOSITIONS AND METHODS FOR USE OF (R) -PRAMIPEXOL
IL208946A0 (en) Immunomodulating compositions and methods of use thereof
EP2231665A4 (en) NEW COMPOSITIONS AND METHODS OF USE
EP2384120A4 (en) AUXILIARY COMPOSITIONS AND METHOD FOR THEIR USE
EP2315600A4 (en) COMPOSITIONS AND METHODS RELATING TO SIRT1 FUNCTION
EP2453743A4 (en) N-ACETYL-CYSTEIN COMPOSITIONS AND METHODS FOR IMPROVED THERAPEUTIC EFFECT OF ACETAMINOPHES
EP2501414A4 (en) SMNDELTA7 DEGRON: NEW COMPOSITIONS AND METHODS OF USE
HK1151438A1 (en) Gas-effusing compositions and methods of making and using same
GB0812890D0 (en) Compositions and methods of making compositions
ZA201003964B (en) Compositions for and methods of enhancing the immune response to antigens
IL207827A0 (en) Apoaequorin-containing compositions and methods of using same
PL2328402T3 (pl) Sposoby i kompozycje do wydłużenia okresu przechowywania owoców
HK1182311A1 (en) Nutritive compositions and methods of using same
HK1166953A1 (en) Compositions and methods of use
AU2009900926A0 (en) Compositions and methods for enhancing immune responses