CA2702584A1 - Methods, compositions and kits for the improved detection of small rna molecules - Google Patents
Methods, compositions and kits for the improved detection of small rna molecules Download PDFInfo
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- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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- C12Q2521/10—Nucleotidyl transfering
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| PCT/US2008/079169 WO2009048928A1 (en) | 2007-10-09 | 2008-10-08 | Methods, compositions and kits for the improved detection of small rna molecules |
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| CA2702584A1 true CA2702584A1 (en) | 2009-04-16 |
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| US8637276B2 (en) * | 2007-10-09 | 2014-01-28 | Igor Vassily Kutyavin | Methods, compositions and kits for the improved detection of small RNA molecules |
| US9074248B1 (en) * | 2012-12-18 | 2015-07-07 | Qiagen Gmbh | Primers for helicase dependent amplification and their methods of use |
| KR20160098097A (ko) * | 2015-02-09 | 2016-08-18 | (주) 하임바이오텍 | 마이크로알앤에이 검출용 키트 및 방법 |
| WO2017087943A1 (en) * | 2015-11-20 | 2017-05-26 | Brandeis University | Amplifying and detecting coconut cadang-cadang viroid rna |
| US10913986B2 (en) | 2016-02-01 | 2021-02-09 | The Board Of Regents Of The University Of Nebraska | Method of identifying important methylome features and use thereof |
| WO2018016885A1 (ko) * | 2016-07-21 | 2018-01-25 | 주식회사 하임바이오텍 | 알앤에이 검출용 키트 및 방법 |
| JP7055691B2 (ja) * | 2017-07-11 | 2022-04-18 | 株式会社東芝 | 短鎖核酸伸長用プライマーセット、アッセイキット、短鎖核酸伸長方法、増幅方法及び検出方法 |
| ES3030914T3 (en) * | 2019-11-04 | 2025-07-02 | Mirnax Biosens S L | Bivalent reverse primer |
| EP3901286A1 (en) * | 2020-04-24 | 2021-10-27 | Mirnax Biosens, S.L. | Bivalent reverse primer |
| CN118166080B (zh) * | 2024-04-15 | 2025-04-04 | 苏州市立医院 | 一种无RNA逆转录酶的miRNA一步法检测方法 |
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| CA2562390C (en) | 2004-04-07 | 2014-12-02 | Exiqon A/S | Novel methods for quantification of micrornas and small interfering rnas |
| WO2007127992A2 (en) | 2006-04-28 | 2007-11-08 | Igor Kutyavin | Use of base-modified deoxynucleoside triphosphates |
| US8637276B2 (en) * | 2007-10-09 | 2014-01-28 | Igor Vassily Kutyavin | Methods, compositions and kits for the improved detection of small RNA molecules |
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| US8980558B2 (en) | 2015-03-17 |
| US8637276B2 (en) | 2014-01-28 |
| AU2008310955B2 (en) | 2015-01-29 |
| WO2009048928A1 (en) | 2009-04-16 |
| US20140170666A1 (en) | 2014-06-19 |
| EP2198059B1 (en) | 2014-12-03 |
| US20100304442A1 (en) | 2010-12-02 |
| AU2008310955A1 (en) | 2009-04-16 |
| JP2011501663A (ja) | 2011-01-13 |
| EP2198059A1 (en) | 2010-06-23 |
| ES2526925T3 (es) | 2015-01-16 |
| JP5486501B2 (ja) | 2014-05-07 |
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