CA2698273A1 - Methods and devices for local therapeutic agent delivery to heart valves - Google Patents
Methods and devices for local therapeutic agent delivery to heart valves Download PDFInfo
- Publication number
- CA2698273A1 CA2698273A1 CA2698273A CA2698273A CA2698273A1 CA 2698273 A1 CA2698273 A1 CA 2698273A1 CA 2698273 A CA2698273 A CA 2698273A CA 2698273 A CA2698273 A CA 2698273A CA 2698273 A1 CA2698273 A1 CA 2698273A1
- Authority
- CA
- Canada
- Prior art keywords
- therapeutic agent
- valve
- delivery
- distal end
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M2025/0024—Expandable catheters or sheaths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1086—Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97046407P | 2007-09-06 | 2007-09-06 | |
| US60/970,464 | 2007-09-06 | ||
| PCT/US2008/075408 WO2009033026A1 (en) | 2007-09-06 | 2008-09-05 | Methods and devices for local therapeutic agent delivery to heart valves |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2698273A1 true CA2698273A1 (en) | 2009-03-12 |
Family
ID=39945598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2698273A Abandoned CA2698273A1 (en) | 2007-09-06 | 2008-09-05 | Methods and devices for local therapeutic agent delivery to heart valves |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8556880B2 (https=) |
| EP (1) | EP2195071A1 (https=) |
| JP (1) | JP2010537788A (https=) |
| CN (1) | CN101883605A (https=) |
| CA (1) | CA2698273A1 (https=) |
| WO (1) | WO2009033026A1 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005003632A1 (de) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Katheter für die transvaskuläre Implantation von Herzklappenprothesen |
| US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
| US8182446B2 (en) | 2007-09-12 | 2012-05-22 | Cook Medical Technologies | Balloon catheter for delivering a therapeutic agent |
| US8100855B2 (en) * | 2007-09-17 | 2012-01-24 | Abbott Cardiovascular Systems, Inc. | Methods and devices for eluting agents to a vessel |
| US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
| WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
| US8034022B2 (en) | 2008-04-08 | 2011-10-11 | Cook Medical Technologies Llc | Weeping balloon catheter |
| EP2419167A1 (en) * | 2009-04-13 | 2012-02-22 | Cook Medical Technologies LLC | Coated balloon catheter |
| US20110022026A1 (en) * | 2009-07-21 | 2011-01-27 | Lake Region Manufacturing, Inc. d/b/a Lake Region Medical. Inc. | Methods and Devices for Delivering Drugs Using Drug-Delivery or Drug-Coated Guidewires |
| US9227041B2 (en) | 2010-04-09 | 2016-01-05 | Boston Scientific Scimed, Inc. | Balloon catheters with fibers for delivery of therapeutic agent and methods of making the same |
| US20110282198A1 (en) * | 2010-05-17 | 2011-11-17 | Numed, Inc. | Rapid response angiographic catheter |
| US10856978B2 (en) | 2010-05-20 | 2020-12-08 | Jenavalve Technology, Inc. | Catheter system |
| CN103002833B (zh) | 2010-05-25 | 2016-05-11 | 耶拿阀门科技公司 | 人工心脏瓣及包括人工心脏瓣和支架的经导管输送的内假体 |
| US20120065506A1 (en) * | 2010-09-10 | 2012-03-15 | Scott Smith | Mechanical, Electromechanical, and/or Elastographic Assessment for Renal Nerve Ablation |
| EP2438933A1 (en) | 2010-09-17 | 2012-04-11 | Eurocor Gmbh | Device for use in treatment of heart valve disease and endocarditis |
| CA2827956C (en) * | 2011-02-23 | 2019-05-07 | Ams Research Corporation | Drug releasing pelvic treatment system and method |
| US20120259269A1 (en) | 2011-04-08 | 2012-10-11 | Tyco Healthcare Group Lp | Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery |
| US9084627B2 (en) * | 2011-10-18 | 2015-07-21 | Boston Scientific Scimed, Inc. | Atherectomy positioning device |
| WO2013171276A1 (en) * | 2012-05-16 | 2013-11-21 | Endovascular Development AB | An assembly with a guide tube, a fixator for attaching to a blood vessel, and a pump |
| CN107837453A (zh) * | 2012-09-11 | 2018-03-27 | 本土心血管公司 | 用于向靶组织给药的装置和方法 |
| WO2014089519A1 (en) | 2012-12-07 | 2014-06-12 | Bartlett Ii Rush L | System for reducing local discomfort |
| US20150039337A1 (en) * | 2013-07-31 | 2015-02-05 | Elwha Llc | Managing a risk of a liability that is incurred if one or more subjects each treated for a respective condition are retreated within a respective specified time period |
| US9940683B2 (en) | 2013-07-31 | 2018-04-10 | Elwha Llc | Managing a risk of a liability that is incurred if a subject treated for a condition is retreated within a specified time period |
| WO2015028209A1 (en) | 2013-08-30 | 2015-03-05 | Jenavalve Technology Gmbh | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
| EP3060174B1 (en) * | 2013-10-22 | 2020-05-27 | Concievalve LLC | Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis |
| US10286190B2 (en) | 2013-12-11 | 2019-05-14 | Cook Medical Technologies Llc | Balloon catheter with dynamic vessel engaging member |
| CN104906682A (zh) | 2014-01-24 | 2015-09-16 | 史蒂文·沙勒布瓦 | 铰接气囊导管及其使用方法 |
| US11000658B2 (en) | 2014-05-18 | 2021-05-11 | Awair, Inc. | Device to reduce discomfort in the upper airway |
| WO2016150806A1 (en) | 2015-03-20 | 2016-09-29 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath |
| CN107530168B (zh) | 2015-05-01 | 2020-06-09 | 耶拿阀门科技股份有限公司 | 在心脏瓣膜替换中具有降低的起搏器比例的装置和方法 |
| CN109475419B (zh) | 2016-05-13 | 2021-11-09 | 耶拿阀门科技股份有限公司 | 用于通过引导鞘和装载系统来递送心脏瓣膜假体的心脏瓣膜假体递送系统和方法 |
| CN110392557A (zh) | 2017-01-27 | 2019-10-29 | 耶拿阀门科技股份有限公司 | 心脏瓣膜模拟 |
| WO2018218348A1 (en) * | 2017-05-30 | 2018-12-06 | Interface Biologics, Inc. | Prosthetic valves having a modified surface |
| CN107019530B (zh) * | 2017-06-02 | 2023-09-08 | 上海捍宇医疗科技股份有限公司 | 一种跨瓣器 |
| US10105154B1 (en) | 2017-11-09 | 2018-10-23 | Pebble Hill Partners, Llc | Basket for a catheter device |
| US11752122B2 (en) * | 2018-02-02 | 2023-09-12 | Oklahoma Medical Research Foundation | N-acetylcysteine attenuates aortic stenosis progression by inhibiting shear-mediated TGF-beta activation and signaling |
| US12569343B2 (en) | 2019-11-18 | 2026-03-10 | Hvr Cardio Oy | Catheter for manipulating anatomical structure and relative position of the catheter and the anatomical structure |
| CN120152682A (zh) | 2022-11-09 | 2025-06-13 | 耶拿阀门科技公司 | 用于顺序地部署可扩张植入物的导管系统 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4531936A (en) | 1981-01-29 | 1985-07-30 | Gordon Robert T | Device and method for the selective delivery of drugs to the myocardium |
| US4950239A (en) | 1988-08-09 | 1990-08-21 | Worldwide Medical Plastics Inc. | Angioplasty balloons and balloon catheters |
| ES2043289T3 (es) | 1989-09-25 | 1993-12-16 | Schneider Usa Inc | La extrusion de capas multiples como procedimiento para hacer balones de angioplastia. |
| US5290306A (en) | 1989-11-29 | 1994-03-01 | Cordis Corporation | Puncture resistant balloon catheter |
| US5195969A (en) | 1991-04-26 | 1993-03-23 | Boston Scientific Corporation | Co-extruded medical balloons and catheter using such balloons |
| US5599352A (en) | 1992-03-19 | 1997-02-04 | Medtronic, Inc. | Method of making a drug eluting stent |
| US5500180A (en) | 1992-09-30 | 1996-03-19 | C. R. Bard, Inc. | Method of making a distensible dilatation balloon using a block copolymer |
| US5336178A (en) * | 1992-11-02 | 1994-08-09 | Localmed, Inc. | Intravascular catheter with infusion array |
| US5512051A (en) | 1993-02-16 | 1996-04-30 | Boston Scientific Corporation | Slip-layered catheter balloon |
| AU7476894A (en) | 1993-07-29 | 1995-02-28 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Method of treating atherosclerosis or restenosis using microtubule stabilizing agent |
| US6146356A (en) | 1994-03-02 | 2000-11-14 | Scimed Life Systems, Inc. | Block copolymer elastomer catheter balloons |
| US5587125A (en) | 1994-08-15 | 1996-12-24 | Schneider (Usa) Inc. | Non-coextrusion method of making multi-layer angioplasty balloons |
| US6425881B1 (en) | 1994-10-05 | 2002-07-30 | Nitrosystems, Inc. | Therapeutic mixture useful in inhibiting lesion formation after vascular injury |
| ES2235174T3 (es) | 1994-10-17 | 2005-07-01 | Kabushikikaisha Igaki Iryo Sekkei | Stent liberador de medicamento. |
| US5713853A (en) * | 1995-06-07 | 1998-02-03 | Interventional Innovations Corporation | Methods for treating thrombosis |
| US5899935A (en) | 1997-08-04 | 1999-05-04 | Schneider (Usa) Inc. | Balloon expandable braided stent with restraint |
| US6242063B1 (en) | 1997-09-10 | 2001-06-05 | Scimed Life Systems, Inc. | Balloons made from liquid crystal polymer blends |
| US6364856B1 (en) | 1998-04-14 | 2002-04-02 | Boston Scientific Corporation | Medical device with sponge coating for controlled drug release |
| US6280414B1 (en) * | 1998-09-30 | 2001-08-28 | Medtronic Ave, Inc. | Method and apparatus for local delivery of therapeutic agent |
| US6695830B2 (en) * | 1999-01-15 | 2004-02-24 | Scimed Life Systems, Inc. | Method for delivering medication into an arterial wall for prevention of restenosis |
| US6626899B2 (en) * | 1999-06-25 | 2003-09-30 | Nidus Medical, Llc | Apparatus and methods for treating tissue |
| US6716242B1 (en) | 1999-10-13 | 2004-04-06 | Peter A. Altman | Pulmonary vein stent and method for use |
| US6572813B1 (en) | 2000-01-13 | 2003-06-03 | Advanced Cardiovascular Systems, Inc. | Balloon forming process |
| US7120910B2 (en) | 2000-03-29 | 2006-10-10 | Canon Kabushiki Kaisha | Control method for image processing apparatus connectable to computer network |
| US6638246B1 (en) * | 2000-11-28 | 2003-10-28 | Scimed Life Systems, Inc. | Medical device for delivery of a biologically active material to a lumen |
| US6544223B1 (en) * | 2001-01-05 | 2003-04-08 | Advanced Cardiovascular Systems, Inc. | Balloon catheter for delivering therapeutic agents |
| US6939376B2 (en) | 2001-11-05 | 2005-09-06 | Sun Biomedical, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
| US7112357B2 (en) | 2002-01-23 | 2006-09-26 | Boston Scientific Scimed, Inc. | Medical devices comprising a multilayer construction |
| US7005097B2 (en) | 2002-01-23 | 2006-02-28 | Boston Scientific Scimed, Inc. | Medical devices employing chain extended polymers |
| DE10244847A1 (de) | 2002-09-20 | 2004-04-01 | Ulrich Prof. Dr. Speck | Medizinische Vorrichtung zur Arzneimittelabgabe |
| US6918929B2 (en) | 2003-01-24 | 2005-07-19 | Medtronic Vascular, Inc. | Drug-polymer coated stent with pegylated styrenic block copolymers |
| US7744620B2 (en) | 2003-07-18 | 2010-06-29 | Intervalve, Inc. | Valvuloplasty catheter |
| US7022104B2 (en) * | 2003-12-08 | 2006-04-04 | Angioscore, Inc. | Facilitated balloon catheter exchange |
| US7601285B2 (en) | 2003-12-31 | 2009-10-13 | Boston Scientific Scimed, Inc. | Medical device with varying physical properties and method for forming same |
| JP2005312964A (ja) * | 2004-04-28 | 2005-11-10 | Medtronic Vascular Inc | 心臓弁修正方法及び心臓弁修正装置 |
| US7470252B2 (en) * | 2004-09-16 | 2008-12-30 | Boston Scientific Scimed, Inc. | Expandable multi-port therapeutic delivery system |
| JP5219518B2 (ja) | 2004-12-09 | 2013-06-26 | ザ ファウンドリー, エルエルシー | 大動脈弁修復 |
| US20070005011A1 (en) | 2005-06-20 | 2007-01-04 | Boston Scientific Scimed, Inc. | Method, system, apparatus, and kit for remote therapeutic delivery |
-
2008
- 2008-09-05 CN CN2008801156274A patent/CN101883605A/zh active Pending
- 2008-09-05 CA CA2698273A patent/CA2698273A1/en not_active Abandoned
- 2008-09-05 EP EP08829666A patent/EP2195071A1/en not_active Withdrawn
- 2008-09-05 WO PCT/US2008/075408 patent/WO2009033026A1/en not_active Ceased
- 2008-09-05 JP JP2010524185A patent/JP2010537788A/ja active Pending
- 2008-09-05 US US12/205,341 patent/US8556880B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009033026A1 (en) | 2009-03-12 |
| US20090069789A1 (en) | 2009-03-12 |
| EP2195071A1 (en) | 2010-06-16 |
| CN101883605A (zh) | 2010-11-10 |
| US8556880B2 (en) | 2013-10-15 |
| JP2010537788A (ja) | 2010-12-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20140905 |