CA2697501A1 - Combination therapy for pancreatic cancer using an antigenic peptide and chemotherapeutic agent - Google Patents
Combination therapy for pancreatic cancer using an antigenic peptide and chemotherapeutic agent Download PDFInfo
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- CA2697501A1 CA2697501A1 CA2697501A CA2697501A CA2697501A1 CA 2697501 A1 CA2697501 A1 CA 2697501A1 CA 2697501 A CA2697501 A CA 2697501A CA 2697501 A CA2697501 A CA 2697501A CA 2697501 A1 CA2697501 A1 CA 2697501A1
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- UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 description 1
- GBABOYUKABKIAF-IELIFDKJSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-IELIFDKJSA-N 0.000 description 1
- 229960002066 vinorelbine Drugs 0.000 description 1
- CILBMBUYJCWATM-PYGJLNRPSA-N vinorelbine ditartrate Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC CILBMBUYJCWATM-PYGJLNRPSA-N 0.000 description 1
- 229940053867 xeloda Drugs 0.000 description 1
- 229950009268 zinostatin Drugs 0.000 description 1
- 229960000641 zorubicin Drugs 0.000 description 1
- FBTUMDXHSRTGRV-ALTNURHMSA-N zorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(\C)=N\NC(=O)C=1C=CC=CC=1)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 FBTUMDXHSRTGRV-ALTNURHMSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/80—Vaccine for a specifically defined cancer
- A61K2039/852—Pancreas
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95792307P | 2007-08-24 | 2007-08-24 | |
| US60/957,923 | 2007-08-24 | ||
| PCT/JP2008/002232 WO2009028150A1 (en) | 2007-08-24 | 2008-08-19 | Combination therapy for pancreatic cancer using an antigenic peptide and chemotherapeutic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2697501A1 true CA2697501A1 (en) | 2009-03-05 |
Family
ID=40386893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2697501A Abandoned CA2697501A1 (en) | 2007-08-24 | 2008-08-19 | Combination therapy for pancreatic cancer using an antigenic peptide and chemotherapeutic agent |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8703713B2 (Direct) |
| EP (1) | EP2195003A4 (Direct) |
| JP (1) | JP5417667B2 (Direct) |
| KR (1) | KR20100047899A (Direct) |
| CN (1) | CN101883577A (Direct) |
| AR (1) | AR068020A1 (Direct) |
| AU (1) | AU2008292966C1 (Direct) |
| BR (1) | BRPI0815726A2 (Direct) |
| CA (1) | CA2697501A1 (Direct) |
| IL (1) | IL204143A (Direct) |
| MX (1) | MX2010002178A (Direct) |
| MY (1) | MY160406A (Direct) |
| NZ (1) | NZ583578A (Direct) |
| RU (1) | RU2472522C2 (Direct) |
| SG (1) | SG183770A1 (Direct) |
| TW (1) | TWI436775B (Direct) |
| UA (1) | UA100702C2 (Direct) |
| WO (1) | WO2009028150A1 (Direct) |
| ZA (1) | ZA201001580B (Direct) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103073620B (zh) | 2002-09-12 | 2014-12-10 | 肿瘤疗法科学股份有限公司 | Kdr肽和包括该肽的疫苗 |
| US20080034017A1 (en) * | 2006-08-04 | 2008-02-07 | Dominic Giampaolo | Links to a common item in a data structure |
| TW201109029A (en) | 2009-06-11 | 2011-03-16 | Oncotherapy Science Inc | Vaccine therapy for choroidal neovascularization |
| WO2011149046A1 (ja) * | 2010-05-28 | 2011-12-01 | 独立行政法人国立がん研究センター | 膵癌治療剤 |
| DE102013214023B4 (de) * | 2013-07-17 | 2015-02-12 | Siemens Aktiengesellschaft | Verfahren zu einem Auswerten und Vergleichen von zeitlich aufeinander folgenden kombinierten medizinischen Bildgebungsuntersuchungen sowie ein medizinisches Bildgebungssystem, das zu einem Ausführen des erfindungsgemäßen Verfahrens ausgelegt ist |
| SG11201702391RA (en) * | 2014-10-09 | 2017-04-27 | Univ Yamaguchi | Car expression vector and car-expressing t cells |
| AU2015333678B2 (en) * | 2014-10-14 | 2020-05-14 | Riptide Bioscience, Inc. | Peptides having anti-inflammatory properties |
| JP7168228B2 (ja) * | 2017-05-19 | 2022-11-09 | 慶應義塾 | 脳神経疾患に対するペプチドワクチン及びペプチドワクチン組成物 |
| US10413584B1 (en) | 2018-08-29 | 2019-09-17 | Riptide Bioscience, Inc. | Peptides having immunomodulatory properties |
| US10548944B1 (en) | 2018-10-19 | 2020-02-04 | Riptide Bioscience, Inc. | Antimicrobial peptides and methods of using the same |
| CN114959031A (zh) * | 2022-05-20 | 2022-08-30 | 上海交通大学医学院附属瑞金医院 | 胰腺腺癌预后评估的标志物组合及其应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB213645A (en) | 1922-12-22 | 1924-03-24 | Frank Lincoln Morse | Improvements in and relating to chain and sprocket wheel gearing |
| US3265572A (en) * | 1961-09-20 | 1966-08-09 | S B Penick And Company | Process for preparing tyrociding and product produced thereby |
| US4526988A (en) * | 1983-03-10 | 1985-07-02 | Eli Lilly And Company | Difluoro antivirals and intermediate therefor |
| WO1994021679A1 (en) | 1993-03-25 | 1994-09-29 | Merck & Co., Inc. | Inhibitor of vascular endothelial cell growth factor |
| US6080728A (en) | 1996-07-16 | 2000-06-27 | Mixson; A. James | Carrier: DNA complexes containing DNA encoding anti-angiogenic peptides and their use in gene therapy |
| DE19638745C2 (de) | 1996-09-11 | 2001-05-10 | Schering Ag | Monoklonale Antikörper gegen die extrazelluläre Domäne des menschlichen VEGF - Rezeptorproteins (KDR) |
| WO1998031794A1 (fr) | 1997-01-17 | 1998-07-23 | Toa Gosei Co., Ltd. | Polypeptide liant le facteur vegf |
| AU2299099A (en) | 1998-02-04 | 1999-08-23 | Kyowa Hakko Kogyo Co. Ltd. | Antibodies against human vegf receptor kdr |
| GB9804121D0 (en) | 1998-02-26 | 1998-04-22 | Cancer Res Campaign Tech | Anti-angiogenic vaccines: materials and methods relating thereto |
| AU3850299A (en) | 1998-05-20 | 1999-12-06 | Kyowa Hakko Kogyo Co. Ltd. | Vegf activity inhibitors |
| US7087411B2 (en) * | 1999-06-08 | 2006-08-08 | Regeneron Pharmaceuticals, Inc. | Fusion protein capable of binding VEGF |
| US7264810B2 (en) | 2001-01-19 | 2007-09-04 | Cytos Biotechnology Ag | Molecular antigen array |
| CU23178A1 (es) * | 2002-04-15 | 2006-09-22 | Ct Ingenieria Genetica Biotech | INMUNOTERAPIA ACTIVA ANTIANGIOGéNICA |
| CN103073620B (zh) * | 2002-09-12 | 2014-12-10 | 肿瘤疗法科学股份有限公司 | Kdr肽和包括该肽的疫苗 |
| AU2003291726A1 (en) | 2002-11-04 | 2004-06-07 | Xenoport, Inc. | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof |
| AU2005222384A1 (en) * | 2004-03-05 | 2005-09-22 | Vegenics Limited | Growth factor binding constructs materials and methods |
| JP2008501652A (ja) * | 2004-06-03 | 2008-01-24 | エフ．ホフマン−ラ ロシュ アーゲー | ゲムシタビン及びｅｇｆｒインヒビターによる治療 |
| US7691827B2 (en) | 2004-12-17 | 2010-04-06 | Eli Lilly And Company | Amide prodrug of gemcitabine, compositions and use thereof |
| US20060216288A1 (en) * | 2005-03-22 | 2006-09-28 | Amgen Inc | Combinations for the treatment of cancer |
| KR101493775B1 (ko) | 2007-02-16 | 2015-02-16 | 온코세라피 사이언스 가부시키가이샤 | 맥락막 신생혈관용 백신 치료 |
-
2008
- 2008-08-13 TW TW097130789A patent/TWI436775B/zh not_active IP Right Cessation
- 2008-08-19 SG SG2012063046A patent/SG183770A1/en unknown
- 2008-08-19 EP EP08828542A patent/EP2195003A4/en not_active Withdrawn
- 2008-08-19 BR BRPI0815726A patent/BRPI0815726A2/pt not_active IP Right Cessation
- 2008-08-19 UA UAA201002881A patent/UA100702C2/ru unknown
- 2008-08-19 US US12/674,754 patent/US8703713B2/en not_active Expired - Fee Related
- 2008-08-19 KR KR1020107005967A patent/KR20100047899A/ko not_active Ceased
- 2008-08-19 CN CN2008801133893A patent/CN101883577A/zh active Pending
- 2008-08-19 WO PCT/JP2008/002232 patent/WO2009028150A1/en not_active Ceased
- 2008-08-19 AU AU2008292966A patent/AU2008292966C1/en not_active Ceased
- 2008-08-19 MX MX2010002178A patent/MX2010002178A/es active IP Right Grant
- 2008-08-19 RU RU2010111139/15A patent/RU2472522C2/ru not_active IP Right Cessation
- 2008-08-19 NZ NZ583578A patent/NZ583578A/en not_active IP Right Cessation
- 2008-08-19 MY MYPI2010000779A patent/MY160406A/en unknown
- 2008-08-19 CA CA2697501A patent/CA2697501A1/en not_active Abandoned
- 2008-08-19 JP JP2010506728A patent/JP5417667B2/ja not_active Expired - Fee Related
- 2008-08-22 AR ARP080103679A patent/AR068020A1/es unknown
-
2010
- 2010-02-24 IL IL204143A patent/IL204143A/en not_active IP Right Cessation
- 2010-03-04 ZA ZA2010/01580A patent/ZA201001580B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009028150A1 (en) | 2009-03-05 |
| BRPI0815726A2 (pt) | 2016-01-05 |
| TW200914037A (en) | 2009-04-01 |
| AU2008292966B2 (en) | 2012-07-19 |
| JP2010536714A (ja) | 2010-12-02 |
| JP5417667B2 (ja) | 2014-02-19 |
| RU2472522C2 (ru) | 2013-01-20 |
| KR20100047899A (ko) | 2010-05-10 |
| SG183770A1 (en) | 2012-09-27 |
| NZ583578A (en) | 2012-07-27 |
| TWI436775B (zh) | 2014-05-11 |
| US20110082088A1 (en) | 2011-04-07 |
| UA100702C2 (ru) | 2013-01-25 |
| AU2008292966A1 (en) | 2009-03-05 |
| IL204143A (en) | 2013-04-30 |
| AU2008292966C1 (en) | 2013-03-14 |
| MY160406A (en) | 2017-03-15 |
| EP2195003A4 (en) | 2011-07-06 |
| RU2010111139A (ru) | 2011-09-27 |
| ZA201001580B (en) | 2011-02-23 |
| AR068020A1 (es) | 2009-10-28 |
| CN101883577A (zh) | 2010-11-10 |
| EP2195003A1 (en) | 2010-06-16 |
| MX2010002178A (es) | 2010-03-18 |
| US8703713B2 (en) | 2014-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130719 |
|
| FZDE | Discontinued |
Effective date: 20160310 |