CA2692013C - Modulateurs du recepteur ccr9 et leurs procedes d'utilisation - Google Patents
Modulateurs du recepteur ccr9 et leurs procedes d'utilisation Download PDFInfo
- Publication number
- CA2692013C CA2692013C CA2692013A CA2692013A CA2692013C CA 2692013 C CA2692013 C CA 2692013C CA 2692013 A CA2692013 A CA 2692013A CA 2692013 A CA2692013 A CA 2692013A CA 2692013 C CA2692013 C CA 2692013C
- Authority
- CA
- Canada
- Prior art keywords
- mmol
- thiophene
- alkyl
- tert
- butyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96264007P | 2007-07-30 | 2007-07-30 | |
| US60/962,640 | 2007-07-30 | ||
| PCT/US2008/009142 WO2009017719A2 (fr) | 2007-07-30 | 2008-07-28 | Modulateurs du récepteur ccr9 et leurs procédés d'utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2692013A1 CA2692013A1 (fr) | 2009-02-05 |
| CA2692013C true CA2692013C (fr) | 2012-08-28 |
Family
ID=40305125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2692013A Expired - Fee Related CA2692013C (fr) | 2007-07-30 | 2008-07-28 | Modulateurs du recepteur ccr9 et leurs procedes d'utilisation |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP2220065A2 (fr) |
| KR (1) | KR20100033418A (fr) |
| AU (1) | AU2008282903B2 (fr) |
| CA (1) | CA2692013C (fr) |
| MX (1) | MX2010001187A (fr) |
| SG (1) | SG183667A1 (fr) |
| WO (1) | WO2009017719A2 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2011007424A (es) | 2009-01-12 | 2011-08-12 | Icagen Inc | Derivados de sulfonamida. |
| JP2013525368A (ja) * | 2010-04-23 | 2013-06-20 | キネタ・インコーポレイテツド | 抗ウイルス性化合物 |
| US9145407B2 (en) | 2010-07-09 | 2015-09-29 | Pfizer Limited | Sulfonamide compounds |
| CN103370307B (zh) * | 2010-10-12 | 2016-05-25 | 扎夫根股份有限公司 | 磺酰胺化合物及其制备方法和使用方法 |
| TW201512171A (zh) | 2013-04-19 | 2015-04-01 | Pfizer Ltd | 化學化合物 |
| WO2023074408A1 (fr) * | 2021-10-28 | 2023-05-04 | 四国化成工業株式会社 | Composé thiophène, son procédé de synthèse et composition contenant ledit composé thiophène |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE229949T1 (de) * | 1996-10-16 | 2003-01-15 | American Cyanamid Co | Herstellung und verwendung von ortho-sulfonamido- heteroarylhydroxamsäuren als matrix- metalloproteinase und tace inhibitoren |
| JP3972163B2 (ja) * | 1999-06-18 | 2007-09-05 | 株式会社大塚製薬工場 | ホスホン酸ジエステル誘導体 |
| WO2004073634A2 (fr) * | 2003-02-20 | 2004-09-02 | Encysive Pharmaceuticals Inc. | Antagonistes du recepteur de l'urotensine-ii de la phenylenediamine et antagonistes du ccr-9 |
-
2008
- 2008-07-28 MX MX2010001187A patent/MX2010001187A/es not_active Application Discontinuation
- 2008-07-28 AU AU2008282903A patent/AU2008282903B2/en not_active Ceased
- 2008-07-28 SG SG2012056255A patent/SG183667A1/en unknown
- 2008-07-28 CA CA2692013A patent/CA2692013C/fr not_active Expired - Fee Related
- 2008-07-28 EP EP08794832A patent/EP2220065A2/fr not_active Withdrawn
- 2008-07-28 WO PCT/US2008/009142 patent/WO2009017719A2/fr active Application Filing
- 2008-07-28 KR KR1020107001995A patent/KR20100033418A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009017719A2 (fr) | 2009-02-05 |
| WO2009017719A8 (fr) | 2010-02-11 |
| CA2692013A1 (fr) | 2009-02-05 |
| WO2009017719A3 (fr) | 2009-04-23 |
| SG183667A1 (en) | 2012-09-27 |
| AU2008282903B2 (en) | 2011-06-30 |
| EP2220065A2 (fr) | 2010-08-25 |
| MX2010001187A (es) | 2010-03-04 |
| AU2008282903A1 (en) | 2009-02-05 |
| KR20100033418A (ko) | 2010-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20140729 |