CA2689913C - Rtef-1 variants and the use thereof for inhibition of angiogenesis - Google Patents
Rtef-1 variants and the use thereof for inhibition of angiogenesis Download PDFInfo
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- CA2689913C CA2689913C CA2689913A CA2689913A CA2689913C CA 2689913 C CA2689913 C CA 2689913C CA 2689913 A CA2689913 A CA 2689913A CA 2689913 A CA2689913 A CA 2689913A CA 2689913 C CA2689913 C CA 2689913C
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- C07K—PEPTIDES
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C07K—PEPTIDES
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- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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Landscapes
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Applications Claiming Priority (3)
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| US94224907P | 2007-06-06 | 2007-06-06 | |
| US60/942,249 | 2007-06-06 | ||
| PCT/US2008/066058 WO2008154351A1 (en) | 2007-06-06 | 2008-06-06 | Rtef-1 variants and the use thereof for inhibition of angiogenesis |
Publications (2)
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| CA2689913A1 CA2689913A1 (en) | 2008-12-18 |
| CA2689913C true CA2689913C (en) | 2014-10-07 |
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| CA2689913A Expired - Fee Related CA2689913C (en) | 2007-06-06 | 2008-06-06 | Rtef-1 variants and the use thereof for inhibition of angiogenesis |
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| US8221753B2 (en) | 2009-09-30 | 2012-07-17 | Tracon Pharmaceuticals, Inc. | Endoglin antibodies |
| KR101553740B1 (ko) * | 2009-08-17 | 2015-09-17 | 트라콘 파마수티칼즈, 인코포레이티드 | 항엔도글린 항체 및 항ｖｅｇｆ 제제를 사용한 암 치료를 위한 병용 요법 |
| US8785385B2 (en) | 2010-04-19 | 2014-07-22 | Research Development Foundation | RTEF-1 variants and uses thereof |
| IT1405683B1 (it) * | 2010-10-18 | 2014-01-24 | Istituto Giannina Gaslini | Vettori lipidici veicolanti silenziatori genici |
| EP2825191B1 (en) | 2012-03-16 | 2019-08-28 | University Health Network | Soluble toso protein and its use in treating autoimmune disorders |
| UA115789C2 (uk) | 2012-09-05 | 2017-12-26 | Трейкон Фармасутікалз, Інк. | Композиція антитіла до cd105 та її застосування |
| CA2917077A1 (en) | 2013-07-03 | 2015-01-08 | University Health Network | Antibodies to toso |
| WO2015130783A1 (en) * | 2014-02-25 | 2015-09-03 | Research Development Foundation | Sty peptides for inhibition of angiogenesis |
| CA2966905A1 (en) | 2014-11-12 | 2016-05-19 | Tracon Pharmaceuticals, Inc. | Anti-endoglin antibodies and uses thereof |
| US9926375B2 (en) | 2014-11-12 | 2018-03-27 | Tracon Pharmaceuticals, Inc. | Anti-endoglin antibodies and uses thereof |
| TWI843989B (zh) | 2021-02-19 | 2024-06-01 | 美商美威高能離子醫療系統公司 | 用於粒子治療系統之支架 |
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| WO1995020975A1 (en) | 1994-02-04 | 1995-08-10 | The Regents Of The University Of California | Tef-1 isoforms and uses thereof |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US7575924B2 (en) | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
| US7122181B2 (en) | 2000-12-19 | 2006-10-17 | Research Development Foundation | Lentiviral vector-mediated gene transfer and uses thereof |
| US7183388B2 (en) | 2001-03-30 | 2007-02-27 | The Regents Of The University Of California | Anti-MUC-1 single chain antibodies for tumor targeting |
| US20060223114A1 (en) | 2001-04-26 | 2006-10-05 | Avidia Research Institute | Protein scaffolds and uses thereof |
| DK1412493T3 (da) | 2001-08-02 | 2012-01-09 | Inst Clayton De La Rech | Fremgangsmåder og sammensætninger der angår forbedrede lentiviral-vektor.-produktionsystemer |
| WO2005034881A2 (en) * | 2003-10-10 | 2005-04-21 | Beth Israel Deaconess Medical Center | Methods and compositions for treating conditions involving abnormal angiogenesis |
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| WO2006055689A2 (en) | 2004-11-16 | 2006-05-26 | Avidia Research Institute | Protein scaffolds and uses thereof |
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2009
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2013
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2016
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Also Published As
| Publication number | Publication date |
|---|---|
| ATE553771T1 (de) | 2012-05-15 |
| CA2689913A1 (en) | 2008-12-18 |
| CN101970472A (zh) | 2011-02-09 |
| EP2170938B1 (en) | 2012-04-18 |
| WO2008154351A9 (en) | 2010-01-14 |
| AU2008261969B2 (en) | 2013-06-06 |
| EP2170938A1 (en) | 2010-04-07 |
| US20090117119A1 (en) | 2009-05-07 |
| US20170081377A1 (en) | 2017-03-23 |
| US8748379B2 (en) | 2014-06-10 |
| JP2013215210A (ja) | 2013-10-24 |
| US20140322205A1 (en) | 2014-10-30 |
| JP2010528663A (ja) | 2010-08-26 |
| WO2008154351A1 (en) | 2008-12-18 |
| IL202338A0 (en) | 2011-08-01 |
| CN101970472B (zh) | 2013-10-30 |
| US9937269B2 (en) | 2018-04-10 |
| IL202338A (en) | 2014-03-31 |
| DK2170938T3 (da) | 2012-07-16 |
| US9512423B2 (en) | 2016-12-06 |
| JP5410416B2 (ja) | 2014-02-05 |
| AU2008261969A1 (en) | 2008-12-18 |
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