CA2689569C - Linear expression constructs for production of influenza virus particles - Google Patents
Linear expression constructs for production of influenza virus particles Download PDFInfo
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- CA2689569C CA2689569C CA2689569A CA2689569A CA2689569C CA 2689569 C CA2689569 C CA 2689569C CA 2689569 A CA2689569 A CA 2689569A CA 2689569 A CA2689569 A CA 2689569A CA 2689569 C CA2689569 C CA 2689569C
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- 230000005030 transcription termination Effects 0.000 description 1
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- 239000012588 trypsin Substances 0.000 description 1
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16141—Use of virus, viral particle or viral elements as a vector
- C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94665107P | 2007-06-27 | 2007-06-27 | |
| US60/946,651 | 2007-06-27 | ||
| EP07450177A EP2045323A1 (en) | 2007-10-05 | 2007-10-05 | Linear expression constructs for production of influenza virus particles |
| EP07450177.6 | 2007-10-05 | ||
| PCT/EP2008/058182 WO2009000891A2 (en) | 2007-06-27 | 2008-06-26 | Linear expression constructs for production of influenza virus particles |
Publications (2)
| Publication Number | Publication Date |
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| CA2689569A1 CA2689569A1 (en) | 2008-12-31 |
| CA2689569C true CA2689569C (en) | 2020-10-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2689569A Active CA2689569C (en) | 2007-06-27 | 2008-06-26 | Linear expression constructs for production of influenza virus particles |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100129399A1 (enExample) |
| EP (2) | EP2045323A1 (enExample) |
| CN (1) | CN101952427A (enExample) |
| AU (1) | AU2008267180B2 (enExample) |
| CA (1) | CA2689569C (enExample) |
| EA (1) | EA017456B1 (enExample) |
| IN (1) | IN2009KN04355A (enExample) |
| NZ (1) | NZ582102A (enExample) |
| WO (1) | WO2009000891A2 (enExample) |
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| US9091510B2 (en) | 2007-03-21 | 2015-07-28 | Schott Corporation | Transparent armor system and method of manufacture |
| EP2072058A1 (en) | 2007-12-21 | 2009-06-24 | Avir Green Hills Biotechnology Research Development Trade Ag | Modified influenza virus |
| EP2233568A1 (en) * | 2009-03-19 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade AG | Novel method for generation of RNA virus |
| WO2010133964A1 (en) | 2009-05-21 | 2010-11-25 | Novartis Ag | Reverse genetics using non-endogenous pol i promoters |
| US9821052B2 (en) | 2009-07-31 | 2017-11-21 | Seqirus UK Limited | Reverse genetics systems |
| CN102741399A (zh) | 2009-10-20 | 2012-10-17 | 诺华有限公司 | 用于病毒拯救的改良反向遗传方法 |
| CN103237890A (zh) * | 2010-06-02 | 2013-08-07 | 巴克斯特保健股份有限公司 | 用于产生rna 病毒的方法和辅助病毒 |
| CN102495208B (zh) * | 2011-10-24 | 2014-03-26 | 山东省农业科学院畜牧兽医研究所 | 禽流感病毒rt-pcr elisa试剂盒 |
| WO2013067652A1 (en) * | 2011-11-10 | 2013-05-16 | Beijing Advaccine Biotechnology Co., Ltd. | Facilitator-dna combination vaccine |
| AU2013205478B9 (en) | 2012-03-02 | 2014-11-20 | Seqirus UK Limited | Influenza virus reassortment |
| US9708585B2 (en) | 2012-12-03 | 2017-07-18 | Seqirus UK Limited | Influenza virus reassortment |
| AU2014229255B2 (en) | 2013-03-13 | 2018-12-13 | Novartis Ag | Influenza B virus reassortment |
| DE202013005130U1 (de) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza Virus Reassortierung |
| DE202013005100U1 (de) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza Virus Reassortierung |
| CA2914604A1 (en) | 2013-06-06 | 2014-12-11 | Novartis Ag | Influenza virus reassortment |
| HK1254344A1 (zh) | 2015-06-26 | 2019-07-19 | Seqirus UK Limited | 抗原匹配的流感疫苗 |
| JP6830070B2 (ja) | 2015-07-07 | 2021-02-17 | セキラス ユーケー リミテッドＳｅｑｉｒｕｓ ＵＫ Ｌｉｍｉｔｅｄ | インフルエンザ効力アッセイ |
| IL293031A (en) | 2019-11-18 | 2022-07-01 | Seqirus Pty Ltd | Method for producing reassortant influenza viruses |
Family Cites Families (11)
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| ES2400445T3 (es) * | 1998-06-12 | 2013-04-09 | Mount Sinai School Of Medicine | Virus atenuados con cadena de polaridad negativa con actividad antagonista de interferón alterada para uso como vacunas y productos farmacéuticos |
| DK1098961T3 (da) * | 1998-06-12 | 2008-05-26 | Andrej Y Dr Egorov | Gensplejsede svækkede vira, der inducerer interferon |
| WO2000056914A1 (en) * | 1999-03-24 | 2000-09-28 | Gene Therapy Systems, Inc. | Method for generating transcriptionally active dna fragments |
| EP2910629B1 (en) * | 1999-04-06 | 2018-09-19 | Wisconsin Alumni Research Foundation | Recombinant influenza viruses for vaccines and gene therapy |
| DE122008000056I1 (de) * | 1999-07-14 | 2009-04-09 | Sinai School Medicine | In vitro-rekonstitution von segmentierten negativstrang-rna-viren |
| CN101580849B (zh) * | 2000-04-28 | 2012-11-21 | 圣朱德儿童研究医院 | 用于产生感染性流感病毒的dna转染系统 |
| DK1499348T3 (en) * | 2002-04-26 | 2015-01-05 | Medimmune Llc | PROCEDURE FOR PREPARING INFECTIOUS INFLUENZA B-VIRA IN CELL CULTURE |
| ES2345492T3 (es) * | 2003-12-23 | 2010-09-24 | Medimmune, Llc | Sistema multiplasmido para la produccion del virus de la gripe. |
| WO2006083286A2 (en) * | 2004-06-01 | 2006-08-10 | Mount Sinai School Of Medicine Of New York University | Genetically engineered swine influenza virus and uses thereof |
| KR20070086344A (ko) * | 2004-11-19 | 2007-08-27 | 위스콘신 얼럼나이 리서어치 화운데이션 | 탠덤 전사 유닛을 갖는 재조합 인플루엔자 벡터 |
| WO2008156681A2 (en) * | 2007-06-14 | 2008-12-24 | Yoshihiro Kawaoka | Adenoviral vectors for influenza virus production |
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2008
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- 2008-06-26 IN IN4355KON2009 patent/IN2009KN04355A/en unknown
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- 2008-06-26 WO PCT/EP2008/058182 patent/WO2009000891A2/en not_active Ceased
- 2008-06-26 CN CN2008800223549A patent/CN101952427A/zh active Pending
Also Published As
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| EA201000076A1 (ru) | 2010-06-30 |
| AU2008267180B2 (en) | 2014-07-10 |
| EP2160462B1 (en) | 2017-07-26 |
| WO2009000891A3 (en) | 2009-02-26 |
| EA017456B1 (ru) | 2012-12-28 |
| US20100129399A1 (en) | 2010-05-27 |
| WO2009000891A2 (en) | 2008-12-31 |
| CA2689569A1 (en) | 2008-12-31 |
| AU2008267180A1 (en) | 2008-12-31 |
| CN101952427A (zh) | 2011-01-19 |
| IN2009KN04355A (enExample) | 2015-07-10 |
| EP2045323A1 (en) | 2009-04-08 |
| NZ582102A (en) | 2012-06-29 |
| EP2160462A2 (en) | 2010-03-10 |
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Effective date: 20130625 |