CA2689569C - Linear expression constructs for production of influenza virus particles - Google Patents
Linear expression constructs for production of influenza virus particles Download PDFInfo
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- CA2689569C CA2689569C CA2689569A CA2689569A CA2689569C CA 2689569 C CA2689569 C CA 2689569C CA 2689569 A CA2689569 A CA 2689569A CA 2689569 A CA2689569 A CA 2689569A CA 2689569 C CA2689569 C CA 2689569C
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16141—Use of virus, viral particle or viral elements as a vector
- C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16161—Methods of inactivation or attenuation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
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- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
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| US94665107P | 2007-06-27 | 2007-06-27 | |
| US60/946,651 | 2007-06-27 | ||
| EP07450177.6 | 2007-10-05 | ||
| EP07450177A EP2045323A1 (en) | 2007-10-05 | 2007-10-05 | Linear expression constructs for production of influenza virus particles |
| PCT/EP2008/058182 WO2009000891A2 (en) | 2007-06-27 | 2008-06-26 | Linear expression constructs for production of influenza virus particles |
Publications (2)
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| CA2689569A1 CA2689569A1 (en) | 2008-12-31 |
| CA2689569C true CA2689569C (en) | 2020-10-27 |
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| CA2689569A Active CA2689569C (en) | 2007-06-27 | 2008-06-26 | Linear expression constructs for production of influenza virus particles |
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| Country | Link |
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| US (1) | US20100129399A1 (enExample) |
| EP (2) | EP2045323A1 (enExample) |
| CN (1) | CN101952427A (enExample) |
| AU (1) | AU2008267180B2 (enExample) |
| CA (1) | CA2689569C (enExample) |
| EA (1) | EA017456B1 (enExample) |
| IN (1) | IN2009KN04355A (enExample) |
| NZ (1) | NZ582102A (enExample) |
| WO (1) | WO2009000891A2 (enExample) |
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| US9091510B2 (en) | 2007-03-21 | 2015-07-28 | Schott Corporation | Transparent armor system and method of manufacture |
| EP2072058A1 (en) | 2007-12-21 | 2009-06-24 | Avir Green Hills Biotechnology Research Development Trade Ag | Modified influenza virus |
| EP2233568A1 (en) * | 2009-03-19 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade AG | Novel method for generation of RNA virus |
| SI2401384T1 (sl) | 2009-05-21 | 2013-01-31 | Novartis Ag | Reverzna genetika z uporabo neendogenih pol i promotorjev |
| JP2013500712A (ja) * | 2009-07-31 | 2013-01-10 | ノバルティス アーゲー | 逆遺伝学系 |
| EP2491117B2 (en) | 2009-10-20 | 2017-06-28 | Novartis AG | Improved reverse genetics methods for virus rescue |
| KR20130115105A (ko) * | 2010-06-02 | 2013-10-21 | 박스터 헬쓰케어 에스에이 | Rna 바이러스를 생산하는 방법 및 헬퍼 바이러스 |
| CN102495208B (zh) * | 2011-10-24 | 2014-03-26 | 山东省农业科学院畜牧兽医研究所 | 禽流感病毒rt-pcr elisa试剂盒 |
| US10206997B2 (en) * | 2011-11-10 | 2019-02-19 | Bin Wang | Facilitator-DNA combination vaccine |
| EP2820126B1 (en) | 2012-03-02 | 2017-05-17 | Seqirus UK Limited | Influenza virus reassortment |
| CA2893429A1 (en) | 2012-12-03 | 2014-06-12 | Synthetic Genomics Vaccines, Inc. | Influenza virus reassortment |
| EP2968512A2 (en) | 2013-03-13 | 2016-01-20 | Novartis AG | Influenza b virus reassortment |
| DE202013005100U1 (de) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza Virus Reassortierung |
| DE202013005130U1 (de) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza Virus Reassortierung |
| HK1222882A1 (zh) | 2013-06-06 | 2017-07-14 | Novartis Ag | 流感病毒重配 |
| EP3313439A2 (en) | 2015-06-26 | 2018-05-02 | Seqirus UK Limited | Antigenically matched influenza vaccines |
| KR102576962B1 (ko) | 2015-07-07 | 2023-09-11 | 세퀴러스 유케이 리미티드 | 인플루엔자 효능 검정 |
| US20230000971A1 (en) | 2019-11-18 | 2023-01-05 | Seqirus Pty Ltd. | Method for producing reassortant influenza viruses |
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| CA2334857C (en) * | 1998-06-12 | 2012-03-20 | Mount Sinai School Of Medicine Of The City University Of New York | Interferon inducing genetically engineered attenuated viruses |
| WO1999064570A1 (en) * | 1998-06-12 | 1999-12-16 | Mount Sinai School Of Medicine Of The City University Of New York | Novel methods and interferon deficient substrates for the propagation of viruses |
| US6280977B1 (en) * | 1999-03-24 | 2001-08-28 | Gene Therapy Systems | Method for generating transcriptionally active DNA fragments |
| CA2365526C (en) * | 1999-04-06 | 2016-07-05 | Wisconsin Alumni Research Foundation | Recombinant influenza viruses for vaccines and gene therapy |
| AU5998400A (en) * | 1999-07-14 | 2001-01-30 | Mount Sinai School Of Medicine Of The City University Of New York, The | In vitro reconstitution of segmented negative-strand rna viruses |
| AU2001259211B2 (en) * | 2000-04-28 | 2006-07-13 | St. Jude Children's Research Hospital | DNA transfection system for the generation of infectious influenza virus |
| AU2003231083A1 (en) * | 2002-04-26 | 2003-11-10 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
| US20050158342A1 (en) * | 2003-12-23 | 2005-07-21 | Medimmune, Inc. | Multi plasmid system for the production of influenza virus |
| DK1773384T3 (en) * | 2004-06-01 | 2015-11-23 | Us Agriculture | GM swine influenza virus and uses thereof |
| AU2005337178A1 (en) * | 2004-11-19 | 2007-04-19 | Wisconsin Alumni Research Foundation | Recombinant influenza vectors with tandem transcription units |
| WO2008156681A2 (en) * | 2007-06-14 | 2008-12-24 | Yoshihiro Kawaoka | Adenoviral vectors for influenza virus production |
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- 2008-06-26 WO PCT/EP2008/058182 patent/WO2009000891A2/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| EA201000076A1 (ru) | 2010-06-30 |
| WO2009000891A3 (en) | 2009-02-26 |
| NZ582102A (en) | 2012-06-29 |
| EP2045323A1 (en) | 2009-04-08 |
| US20100129399A1 (en) | 2010-05-27 |
| AU2008267180A1 (en) | 2008-12-31 |
| IN2009KN04355A (enExample) | 2015-07-10 |
| AU2008267180B2 (en) | 2014-07-10 |
| EA017456B1 (ru) | 2012-12-28 |
| EP2160462A2 (en) | 2010-03-10 |
| CA2689569A1 (en) | 2008-12-31 |
| WO2009000891A2 (en) | 2008-12-31 |
| EP2160462B1 (en) | 2017-07-26 |
| CN101952427A (zh) | 2011-01-19 |
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