CA2687147C - H5 subtype-specific binding proteins useful for h5 avian influenza diagnosis and surveillance - Google Patents

H5 subtype-specific binding proteins useful for h5 avian influenza diagnosis and surveillance Download PDF

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Publication number
CA2687147C
CA2687147C CA2687147A CA2687147A CA2687147C CA 2687147 C CA2687147 C CA 2687147C CA 2687147 A CA2687147 A CA 2687147A CA 2687147 A CA2687147 A CA 2687147A CA 2687147 C CA2687147 C CA 2687147C
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antibody
subtype
binding protein
binding
avian influenza
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CA2687147A
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English (en)
French (fr)
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CA2687147A1 (en
Inventor
Ho Yuen Fern
Du Qing Yun
He Fang
Jimmy Kwang Hwei Sing
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Temasek Life Sciences Laboratory Ltd
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Temasek Life Sciences Laboratory Ltd
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1018Orthomyxoviridae, e.g. influenza virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/11Orthomyxoviridae, e.g. influenza virus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2687147A 2007-05-11 2007-05-11 H5 subtype-specific binding proteins useful for h5 avian influenza diagnosis and surveillance Active CA2687147C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SG2007/000134 WO2008140415A1 (en) 2007-05-11 2007-05-11 H5 subtype-specific binding proteins useful for h5 avian influenza diagnosis and surveillance

Publications (2)

Publication Number Publication Date
CA2687147A1 CA2687147A1 (en) 2008-11-20
CA2687147C true CA2687147C (en) 2016-08-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2687147A Active CA2687147C (en) 2007-05-11 2007-05-11 H5 subtype-specific binding proteins useful for h5 avian influenza diagnosis and surveillance

Country Status (9)

Country Link
US (3) US8540994B2 (sl)
EP (2) EP2155787A4 (sl)
JP (1) JP5597128B2 (sl)
KR (1) KR101421460B1 (sl)
CN (1) CN101687921A (sl)
AU (1) AU2007353481B2 (sl)
CA (1) CA2687147C (sl)
HK (1) HK1161725A1 (sl)
WO (1) WO2008140415A1 (sl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101421460B1 (ko) * 2007-05-11 2014-07-30 테마섹 라이프 사이언스 래보러토리 리미티드 H5 조류 인플루엔자 진단 및 감시를 위해 유용한 h5 서브타입-특이적 결합 단백질
WO2009035412A1 (en) 2007-09-13 2009-03-19 Temasek Life Sciences Laboratory Limited Monoclonal antibodies specific to hemagglutinin from influenza virus h5-subtype and uses thereof
SG183031A1 (en) 2007-09-13 2012-08-30 Temasek Life Sciences Lab Ltd Monoclonal antibodies specific to hemagglutinin and neuraminidase from influenza virus h5-subtype or n1-subtype and uses thereof
JP5490725B2 (ja) * 2008-02-05 2014-05-14 テマセック・ライフ・サイエンシズ・ラボラトリー・リミテッド H5亜型インフルエンザウイルスの普遍的な検出のための結合タンパク質およびエピトープブロッキングelisa
WO2010074656A1 (en) * 2008-12-24 2010-07-01 Temasek Life Sciences Laboratory Limited Monoclonal antibodies specific to the fusion peptide from hemagglutinin from influenza a viruses and uses thereof
WO2012054745A1 (en) * 2010-10-20 2012-04-26 New York Blood Center, Inc. Influenza hemagglutinin-specific monoclonal antibodies for preventing and treating influenza virus infection
CN101993492B (zh) * 2010-11-25 2012-06-27 南京医科大学 抗H5N1型高致病性禽流感scFv抗体及其应用
JP2013087069A (ja) * 2011-10-17 2013-05-13 Toyobo Co Ltd H5亜型インフルエンザウイルスを特異的に認識するモノクローナル抗体
US9969794B2 (en) 2012-05-10 2018-05-15 Visterra, Inc. HA binding agents
TWI702229B (zh) 2014-12-19 2020-08-21 美商再生元醫藥公司 流行性感冒病毒血球凝集素之人類抗體
WO2017083627A1 (en) 2015-11-13 2017-05-18 Visterra, Inc. Compositions and methods for treating and preventing influenza
KR20200115517A (ko) 2018-01-26 2020-10-07 리제너론 파마슈티칼스 인코포레이티드 인플루엔자 헤마글루티닌에 대한 인간 항체
WO2019241188A1 (en) * 2018-06-11 2019-12-19 Glaxosmithkline Consumer Healthcare Holdings (Us) Llc Antibody pairs for use in a rapid influenza b diagnostic test
CA3132521A1 (en) 2019-03-25 2020-10-01 Visterra, Inc. Compositions and methods for treating and preventing influenza
KR102517114B1 (ko) * 2020-08-28 2023-04-03 원광대학교산학협력단 고병원성 조류 인플루엔자 바이러스 h5 아형에 특이적인 단클론항체 및 이를 이용한 신속 진단 키트
KR102605065B1 (ko) * 2021-10-14 2023-11-22 원광대학교산학협력단 고병원성 조류 인플루엔자 바이러스 h5n1에 특이적인 단클론항체 및 이를 이용한 신속 진단 키트

Family Cites Families (18)

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US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
WO2003102246A1 (en) * 2002-05-31 2003-12-11 Penn State Research Foundation Dot-elisa for the detection of animal viruses
AU2002951692A0 (en) * 2002-09-23 2002-10-17 Vital Biotech (Hong Kong) Limited Improvements in or relating to vaccines
US7037707B2 (en) * 2003-09-04 2006-05-02 St. Jude Children's Research Hospital Method for generating influenza viruses and vaccines
US20070003576A1 (en) * 2004-12-09 2007-01-04 Andrea Gambotto Vaccines for the rapid response to pandemic avian influenza
CA2616561C (en) * 2005-07-25 2018-12-18 Avianax, Llc Therapeutic goose antibodies for treatment and prophylaxis of transmittable viral diseases
US7871626B2 (en) * 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
US20070087339A1 (en) * 2005-10-17 2007-04-19 Rangarajan Sampath Compositions for use in identification of influenza viruses
US20070092524A1 (en) * 2005-10-21 2007-04-26 Jacob Nusbacher Method for the treatment and prophylaxis of avian influenza infection
CA2637837A1 (en) * 2006-01-26 2007-08-09 Hx Diagnostics, Inc. Monoclonal antibodies binding to avian influenza virus subtype h5 haemagglutinin and uses thereof
CN101460628B (zh) * 2006-05-05 2013-03-27 淡马锡生命科学研究院有限公司 生物分子表面展示及其用途
EP2035454A2 (en) 2006-05-19 2009-03-18 Amgen, Inc. Antibodies to sars coronavirus
KR101421460B1 (ko) * 2007-05-11 2014-07-30 테마섹 라이프 사이언스 래보러토리 리미티드 H5 조류 인플루엔자 진단 및 감시를 위해 유용한 h5 서브타입-특이적 결합 단백질
WO2009035412A1 (en) * 2007-09-13 2009-03-19 Temasek Life Sciences Laboratory Limited Monoclonal antibodies specific to hemagglutinin from influenza virus h5-subtype and uses thereof
SG183031A1 (en) * 2007-09-13 2012-08-30 Temasek Life Sciences Lab Ltd Monoclonal antibodies specific to hemagglutinin and neuraminidase from influenza virus h5-subtype or n1-subtype and uses thereof
JP5490725B2 (ja) * 2008-02-05 2014-05-14 テマセック・ライフ・サイエンシズ・ラボラトリー・リミテッド H5亜型インフルエンザウイルスの普遍的な検出のための結合タンパク質およびエピトープブロッキングelisa
WO2010074656A1 (en) * 2008-12-24 2010-07-01 Temasek Life Sciences Laboratory Limited Monoclonal antibodies specific to the fusion peptide from hemagglutinin from influenza a viruses and uses thereof

Also Published As

Publication number Publication date
KR20100049506A (ko) 2010-05-12
US20130004944A1 (en) 2013-01-03
US20130004943A1 (en) 2013-01-03
HK1161725A1 (en) 2012-08-03
AU2007353481B2 (en) 2013-08-29
JP2010526880A (ja) 2010-08-05
US20110003278A1 (en) 2011-01-06
EP2155787A4 (en) 2010-06-16
EP2155787A1 (en) 2010-02-24
US8540994B2 (en) 2013-09-24
CA2687147A1 (en) 2008-11-20
WO2008140415A9 (en) 2009-01-15
EP2363415B1 (en) 2013-07-31
US8637645B2 (en) 2014-01-28
US8637644B2 (en) 2014-01-28
AU2007353481A1 (en) 2008-11-20
JP5597128B2 (ja) 2014-10-01
KR101421460B1 (ko) 2014-07-30
CN101687921A (zh) 2010-03-31
EP2363415A3 (en) 2011-12-14
WO2008140415A1 (en) 2008-11-20
EP2363415A2 (en) 2011-09-07

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