CA2684220A1 - Systeme de radiosynthese microfluidique pour biomarqueurs de tomographie par emission de positrons - Google Patents
Systeme de radiosynthese microfluidique pour biomarqueurs de tomographie par emission de positrons Download PDFInfo
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- CA2684220A1 CA2684220A1 CA002684220A CA2684220A CA2684220A1 CA 2684220 A1 CA2684220 A1 CA 2684220A1 CA 002684220 A CA002684220 A CA 002684220A CA 2684220 A CA2684220 A CA 2684220A CA 2684220 A1 CA2684220 A1 CA 2684220A1
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PCT/US2008/060267 WO2008128201A1 (fr) | 2007-04-12 | 2008-04-14 | Système de radiosynthèse microfluidique pour biomarqueurs de tomographie par émission de positrons |
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US7741121B2 (en) | 2006-08-24 | 2010-06-22 | Siemens Medical Solutions Usa, Inc. | System for purification and analysis of radiochemical products yielded by microfluidic synthesis devices |
JP5309312B2 (ja) | 2007-11-01 | 2013-10-09 | Jfeテクノス株式会社 | マイクロチップ、マイクロチップデバイス及びマイクロチップを用いた蒸発操作方法 |
US20100093098A1 (en) * | 2008-10-14 | 2010-04-15 | Siemens Medical Solutions | Nonflow-through appratus and mehod using enhanced flow mechanisms |
US8110148B2 (en) | 2008-11-06 | 2012-02-07 | Siemens Medical Solutions Usa, Inc. | Apparatus and method using rotary flow distribution mechanisms |
JP5438351B2 (ja) * | 2009-03-30 | 2014-03-12 | Jfeテクノス株式会社 | マイクロチップを用いたpet用標識化合物の調剤方法及び装置 |
JP5431764B2 (ja) * | 2009-03-30 | 2014-03-05 | Jfeテクノス株式会社 | マイクロチップを用いたフッ素f−18標識化合物の製造方法及び装置 |
US8273300B2 (en) | 2009-07-09 | 2012-09-25 | Siemens Medical Solutions Usa, Inc. | Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure |
US8435454B2 (en) | 2009-07-09 | 2013-05-07 | Siemens Medical Solutions Usa, Inc. | Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure |
US20110202177A1 (en) * | 2010-02-15 | 2011-08-18 | Siemens Medical Solutions Usa, Inc. | Intuitive Graphical User Interface for Carrying Out Chemical Reactions |
KR101347747B1 (ko) * | 2011-05-13 | 2014-01-06 | 성균관대학교산학협력단 | 열 용융 밸브를 포함하는 방사성 화합물 합성장치 |
WO2012157920A2 (fr) * | 2011-05-13 | 2012-11-22 | 성균관대학교 산학협력단 | Système de synthèse de composés radioactifs comprenant une unité de régulation de température |
KR101288866B1 (ko) * | 2011-05-13 | 2013-07-23 | 성균관대학교산학협력단 | 방사성 화합물 합성을 위한 원격제어시스템 |
KR101293158B1 (ko) * | 2011-05-13 | 2013-08-12 | 성균관대학교산학협력단 | 방사성 화합물 합성모듈 |
KR101288867B1 (ko) * | 2011-05-13 | 2013-07-23 | 성균관대학교산학협력단 | 온도조절유닛을 포함하는 방사성 화합물 합성 시스템 |
US20130004414A1 (en) * | 2011-06-30 | 2013-01-03 | General Electric Company | Devices and methods for reducing radiolysis of radioisotopes |
EP2562150B1 (fr) | 2011-08-26 | 2014-10-15 | FutureChemistry Holding B.V. | Procédé et dispositif pour la production de radiomarqueurs pour animaux domestiques |
CN104011802B (zh) * | 2011-09-30 | 2016-09-07 | 通用电气健康护理有限公司 | 合成器诊断盒模拟器 |
ITTO20120996A1 (it) * | 2012-11-16 | 2014-05-17 | Consiglio Nazionale Ricerche | Procedimento e impianto per la produzione di radiotraccianti pet 18f-fluorurati |
WO2014102944A1 (fr) * | 2012-12-26 | 2014-07-03 | 株式会社日立製作所 | Réacteur pour le marquage d'une molécule biologique et appareil à réaction et procédé de réaction l'utilisant chacun |
US9907867B2 (en) | 2013-09-26 | 2018-03-06 | General Electric Company | Systems, methods and apparatus for manufacturing radioisotopes |
GB201405591D0 (en) | 2014-03-28 | 2014-05-14 | Ge Healthcare Ltd | Heatseal |
KR101689321B1 (ko) * | 2014-05-30 | 2017-01-02 | 성균관대학교산학협력단 | 방사성 화합물 합성 장치용 인터페이스 및 그의 조작방법 |
KR101903695B1 (ko) * | 2016-11-28 | 2018-10-04 | 가천대학교 산학협력단 | 고온 불활성 기체를 이용한 불소-18 화합물 합성장치 |
CN109254018B (zh) * | 2018-09-11 | 2021-12-07 | 华中科技大学同济医学院附属协和医院 | 一种放射性药物的药物代谢动力学成像检测系统 |
EP3972655A4 (fr) * | 2019-05-22 | 2022-07-06 | The Regents of University of California | Radiosynthétiseur de microgouttelettes ultra-compact automatisé |
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JPH0698303B2 (ja) * | 1985-04-25 | 1994-12-07 | 住友重機械工業株式会社 | ミクロ反応及び分取装置 |
CA2134477C (fr) | 1992-05-01 | 1999-07-06 | Peter Wilding | Analyse fondee sur la restriction de l'ecoulement |
EP0724480B1 (fr) * | 1993-10-18 | 1997-11-19 | Imperial Chemical Industries Plc | Procede catalytique |
US6599484B1 (en) | 2000-05-12 | 2003-07-29 | Cti, Inc. | Apparatus for processing radionuclides |
EP1322936A2 (fr) | 2000-10-03 | 2003-07-02 | California Institute Of Technology | Dispositifs microfluidiques et procedes d'utilisation |
GB0206117D0 (en) * | 2002-03-15 | 2002-04-24 | Imaging Res Solutions Ltd | Use of microfabricated devices |
WO2003098219A1 (fr) * | 2002-05-17 | 2003-11-27 | University Of Copenhagen | Mesure par dosage immunoenzymatique (elisa) de l'interaction de novo entre un peptide et une molecule mhc |
US7186383B2 (en) * | 2002-09-27 | 2007-03-06 | Ast Management Inc. | Miniaturized fluid delivery and analysis system |
WO2005057589A2 (fr) | 2003-11-05 | 2005-06-23 | Board Of Regents, The University Of Texas System | Dispositif de synthese de marqueurs radioactifs automatise multifonction |
EP1689675A2 (fr) * | 2003-12-03 | 2006-08-16 | GE Healthcare Limited | Procede et appareil de synthese de phosgene sp 11 /sp c| a l'aide de monoxyde de carbone sp 11 /sp c| concentre et de lumiere ultraviolette |
WO2005066100A1 (fr) * | 2003-12-24 | 2005-07-21 | Ge Healthcare Limited | Procedes permettant de synthetiser, par marquage des isotopes du carbone, des cetones et des amines au moyen de reactions de couplage suzuki utilisant un monoxyde d'isotope du carbone |
JP2008522795A (ja) | 2004-12-03 | 2008-07-03 | カリフォルニア インスティチュート オブ テクノロジー | 化学反応回路を有するマイクロ流体装置 |
US20070031492A1 (en) | 2005-08-02 | 2007-02-08 | Dischino Douglas D | Remote controlled synthesis system |
US8480053B2 (en) | 2005-09-02 | 2013-07-09 | California Institute Of Technology | Method and apparatus for the mechanical actuation of valves in fluidic devices |
WO2007041486A2 (fr) | 2005-09-29 | 2007-04-12 | Siemens Medical Solutions Usa, Inc. | Puce microfluidique capable de synthetiser des molecules radiomarquees a une echelle adaptee a l'imagerie humaine par tomographie par emission de positrons |
GB0524851D0 (en) | 2005-12-06 | 2006-01-11 | Ge Healthcare Ltd | Radiolabelling method using polymers |
EP1981636A4 (fr) * | 2006-02-03 | 2010-06-09 | California Inst Of Techn | Procede et structure microfluidique dotee d'un joint elastomere permeable aux gaz |
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JP2010531295A (ja) | 2010-09-24 |
KR20100005216A (ko) | 2010-01-14 |
CN102083525A (zh) | 2011-06-01 |
WO2008128201A1 (fr) | 2008-10-23 |
KR101176710B1 (ko) | 2012-08-23 |
EP2134461A1 (fr) | 2009-12-23 |
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