CA2680803A1 - Derivatives of the aminated hydroxyquinoline class for treating cancers - Google Patents

Derivatives of the aminated hydroxyquinoline class for treating cancers Download PDF

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Publication number
CA2680803A1
CA2680803A1 CA002680803A CA2680803A CA2680803A1 CA 2680803 A1 CA2680803 A1 CA 2680803A1 CA 002680803 A CA002680803 A CA 002680803A CA 2680803 A CA2680803 A CA 2680803A CA 2680803 A1 CA2680803 A1 CA 2680803A1
Authority
CA
Canada
Prior art keywords
groupe
par
des
étant
est
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002680803A
Other languages
English (en)
French (fr)
Inventor
Jean-Louis Kraus
Olivier Blin
Frederic Champavere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOPHARMED A RESPONSABILITE Ltee Ste
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2680803A1 publication Critical patent/CA2680803A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002680803A 2007-03-23 2008-03-25 Derivatives of the aminated hydroxyquinoline class for treating cancers Abandoned CA2680803A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR07/02154 2007-03-23
FR0702154A FR2913976B1 (fr) 2007-03-23 2007-03-23 Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.
PCT/FR2008/000399 WO2008135671A2 (fr) 2007-03-23 2008-03-25 Dérivés de la classe des hydroxyquinoléines aminées pour le traitement de cancers.

Publications (1)

Publication Number Publication Date
CA2680803A1 true CA2680803A1 (en) 2008-11-13

Family

ID=38686734

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002680803A Abandoned CA2680803A1 (en) 2007-03-23 2008-03-25 Derivatives of the aminated hydroxyquinoline class for treating cancers

Country Status (8)

Country Link
US (2) US8324243B2 (https=)
EP (1) EP2139860A2 (https=)
JP (1) JP5555494B2 (https=)
CN (1) CN101641332B (https=)
AU (1) AU2008248475B2 (https=)
CA (1) CA2680803A1 (https=)
FR (1) FR2913976B1 (https=)
WO (1) WO2008135671A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2913976B1 (fr) * 2007-03-23 2013-04-26 Biopharmed Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.
EP2149567A1 (en) * 2008-07-18 2010-02-03 Bayer Schering Pharma Aktiengesellschaft Cyclic polyamines for binding phosphatidylserine
FR2940289B1 (fr) * 2008-12-23 2014-09-12 Biopharmed Derives de la classe des hydroxyquinoleines aminees pour le traitement du cancer du pancreas
KR101514285B1 (ko) 2013-08-09 2015-04-22 숙명여자대학교산학협력단 아미노다이하이드로퀴놀린 화합물 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 암 질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5736192A (en) * 1980-08-13 1982-02-26 Nippon Oil Co Ltd Metal inactivator and its composition
IL130324A0 (en) * 1999-06-07 2000-06-01 Yeda Res & Dev Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators
US8058442B2 (en) * 2002-11-07 2011-11-15 Technion Research And Development Foundation Ltd. Neuroprotective iron chelators and pharmaceutical compositions comprising them
CN1295218C (zh) * 2004-06-18 2007-01-17 中国科学院广州化学研究所 单官能团8－羟基喹啉金属配合物的烯类单体及其制法和用途
FR2913976B1 (fr) * 2007-03-23 2013-04-26 Biopharmed Derives de la classe des hydroxyquinoleines aminees pour le traitement de cancers.

Also Published As

Publication number Publication date
US8614230B2 (en) 2013-12-24
AU2008248475A1 (en) 2008-11-13
CN101641332A (zh) 2010-02-03
US20130102630A1 (en) 2013-04-25
EP2139860A2 (fr) 2010-01-06
AU2008248475B2 (en) 2013-10-03
WO2008135671A3 (fr) 2009-05-22
CN101641332B (zh) 2014-03-12
FR2913976B1 (fr) 2013-04-26
JP5555494B2 (ja) 2014-07-23
JP2010522147A (ja) 2010-07-01
FR2913976A1 (fr) 2008-09-26
US8324243B2 (en) 2012-12-04
WO2008135671A2 (fr) 2008-11-13
US20100120856A1 (en) 2010-05-13

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130325

FZDE Discontinued

Effective date: 20170329