CA2673260A1 - Compositions de facteur vii et viia - Google Patents
Compositions de facteur vii et viia Download PDFInfo
- Publication number
- CA2673260A1 CA2673260A1 CA002673260A CA2673260A CA2673260A1 CA 2673260 A1 CA2673260 A1 CA 2673260A1 CA 002673260 A CA002673260 A CA 002673260A CA 2673260 A CA2673260 A CA 2673260A CA 2673260 A1 CA2673260 A1 CA 2673260A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- fvii
- polypeptide
- fviia
- reconstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 389
- 229940012413 factor vii Drugs 0.000 title claims abstract description 160
- 229940012414 factor viia Drugs 0.000 title claims description 169
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 232
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 232
- 229920001184 polypeptide Polymers 0.000 claims abstract description 231
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- 102100023804 Coagulation factor VII Human genes 0.000 claims abstract description 158
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- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 20
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- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 19
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- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims description 3
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
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Landscapes
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87094806P | 2006-12-20 | 2006-12-20 | |
| US60/870,948 | 2006-12-20 | ||
| PCT/IB2007/004338 WO2008078189A2 (fr) | 2006-12-20 | 2007-12-18 | Compositions de facteur vii et viia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2673260A1 true CA2673260A1 (fr) | 2008-07-03 |
Family
ID=39431180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002673260A Abandoned CA2673260A1 (fr) | 2006-12-20 | 2007-12-18 | Compositions de facteur vii et viia |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2114379A2 (fr) |
| JP (1) | JP2010513462A (fr) |
| CA (1) | CA2673260A1 (fr) |
| WO (1) | WO2008078189A2 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI465247B (zh) | 2008-04-11 | 2014-12-21 | Catalyst Biosciences Inc | 經修飾的因子ｖｉｉ多肽和其用途 |
| HUE049023T2 (hu) * | 2008-08-15 | 2020-08-28 | Ironwood Pharmaceuticals Inc | Linaklotidot tartalmazó, szájon át történõ beadásra szolgáló készítmények |
| FR2947181B1 (fr) | 2009-06-26 | 2012-05-04 | Lfb Biotechnologies | Composition de facteur vii |
| WO2011017502A2 (fr) * | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprenant du linaclotide |
| UA108636C2 (xx) | 2010-02-17 | 2015-05-25 | Пептид | |
| RS59978B1 (sr) | 2010-08-11 | 2020-03-31 | Ironwood Pharmaceuticals Inc | Stabilne formulacije linaklotida |
| AR083035A1 (es) * | 2010-09-17 | 2013-01-30 | Baxter Int | ESTABILIZACION DE INMUNOGLOBULINAS MEDIANTE UNA FORMULACION ACUOSA CON HISTIDINA A pH ACIDO DEBIL A NEUTRO, COMPOSICION ACUOSA DE INMUNOGLOBULINA |
| ES2369945B1 (es) | 2011-07-29 | 2012-10-15 | Eduardo Anitua Aldecoa | Procedimiento de obtención de una composición que contiene factores de crecimiento a partir de un compuesto sanguíneo, y composición obtenible por dicho procedimiento. |
| DK2776055T3 (en) | 2011-08-17 | 2017-03-06 | Ironwood Pharmaceuticals Inc | TREATMENTS FOR GASTROINTESTINAL DISORDERS |
| KR102058864B1 (ko) | 2013-12-16 | 2019-12-24 | 주식회사 티움바이오 | 인자 vii의 융합 단백질을 포함하는 안정성이 개선된 약학적 조성물 |
| MX2016013667A (es) * | 2014-04-28 | 2017-01-23 | Eisai R&D Man Co Ltd | Formulacion liofilizada de factor de crecimiento hepatico (hgf). |
| US11548926B2 (en) | 2016-03-17 | 2023-01-10 | Eisai R&D Management Co., Ltd. | Method for producing an active hepatocyte growth factor (HGF) |
| CN114728044A (zh) | 2019-08-15 | 2022-07-08 | 介控生化科技公司 | 用于皮下施用和按需求治疗的经修饰的因子vii多肽 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9501040D0 (en) * | 1995-01-19 | 1995-03-08 | Quadrant Holdings Cambridge | Dried composition |
| US6017882A (en) * | 1997-10-23 | 2000-01-25 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6693075B1 (en) * | 1997-10-23 | 2004-02-17 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6423826B1 (en) * | 2000-06-30 | 2002-07-23 | Regents Of The University Of Minnesota | High molecular weight derivatives of vitamin K-dependent polypeptides |
| SI1499719T1 (sl) * | 2002-04-30 | 2011-03-31 | Bayer Healthcare Llc | Polipeptidne variante faktorja VII ali VIIa |
| EP1517698B2 (fr) * | 2002-06-21 | 2017-12-06 | Novo Nordisk Health Care AG | COMPOSITIONS SOLIDES STABILISEES DE POLYPEPTIDES DE FACTEUR VIIa |
| US20060166874A1 (en) * | 2002-09-30 | 2006-07-27 | Haaning Jesper M | Fvii or fviia variants having increased clotting activity |
| EP2298287B1 (fr) * | 2003-12-19 | 2018-04-11 | Novo Nordisk Health Care AG | Compositions stabilisees de polypeptides de facteur VII |
-
2007
- 2007-12-18 CA CA002673260A patent/CA2673260A1/fr not_active Abandoned
- 2007-12-18 JP JP2009542270A patent/JP2010513462A/ja active Pending
- 2007-12-18 EP EP07870424A patent/EP2114379A2/fr not_active Withdrawn
- 2007-12-18 WO PCT/IB2007/004338 patent/WO2008078189A2/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP2114379A2 (fr) | 2009-11-11 |
| WO2008078189A3 (fr) | 2009-03-05 |
| JP2010513462A (ja) | 2010-04-30 |
| WO2008078189A2 (fr) | 2008-07-03 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| EEER | Examination request |
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| FZDE | Dead |
Effective date: 20151008 |