CA2673260A1 - Compositions de facteur vii et viia - Google Patents
Compositions de facteur vii et viia Download PDFInfo
- Publication number
- CA2673260A1 CA2673260A1 CA002673260A CA2673260A CA2673260A1 CA 2673260 A1 CA2673260 A1 CA 2673260A1 CA 002673260 A CA002673260 A CA 002673260A CA 2673260 A CA2673260 A CA 2673260A CA 2673260 A1 CA2673260 A1 CA 2673260A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- fvii
- polypeptide
- fviia
- reconstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 389
- 229940012413 factor vii Drugs 0.000 title claims abstract description 160
- 229940012414 factor viia Drugs 0.000 title claims description 169
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 232
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 232
- 229920001184 polypeptide Polymers 0.000 claims abstract description 231
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- 102100023804 Coagulation factor VII Human genes 0.000 claims abstract description 158
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- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 20
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- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 19
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- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims description 3
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
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Landscapes
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87094806P | 2006-12-20 | 2006-12-20 | |
| US60/870,948 | 2006-12-20 | ||
| PCT/IB2007/004338 WO2008078189A2 (fr) | 2006-12-20 | 2007-12-18 | Compositions de facteur vii et viia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2673260A1 true CA2673260A1 (fr) | 2008-07-03 |
Family
ID=39431180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002673260A Abandoned CA2673260A1 (fr) | 2006-12-20 | 2007-12-18 | Compositions de facteur vii et viia |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2114379A2 (fr) |
| JP (1) | JP2010513462A (fr) |
| CA (1) | CA2673260A1 (fr) |
| WO (1) | WO2008078189A2 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI538916B (zh) | 2008-04-11 | 2016-06-21 | 介控生化科技公司 | 經修飾的因子vii多肽和其用途 |
| CN102186490B (zh) * | 2008-08-15 | 2015-07-29 | 硬木药品公司 | 适合口服给药的鸟苷酸环化酶-c受体激动剂多肽的稳定的固体制剂 |
| FR2947181B1 (fr) * | 2009-06-26 | 2012-05-04 | Lfb Biotechnologies | Composition de facteur vii |
| CA2770077A1 (fr) * | 2009-08-06 | 2011-02-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprenant du linaclotide |
| TR201711271T4 (tr) | 2010-02-17 | 2019-02-21 | Ironwood Pharmaceuticals Inc | Gastrointestinal Bozukluklar İçin Tedaviler |
| PL2603232T3 (pl) | 2010-08-11 | 2020-05-18 | Ironwood Pharmaceuticals, Inc. | Stabilne formulacje linaklotydu |
| KR101879885B1 (ko) * | 2010-09-17 | 2018-07-18 | 박스알타 인코퍼레이티드 | 약산성 내지 중성 ｐｈ에서 히스티딘을 갖는 수성 제형을 통한 면역글로불린의 안정화 |
| ES2369945B1 (es) * | 2011-07-29 | 2012-10-15 | Eduardo Anitua Aldecoa | Procedimiento de obtención de una composición que contiene factores de crecimiento a partir de un compuesto sanguíneo, y composición obtenible por dicho procedimiento. |
| CN104053449B (zh) | 2011-08-17 | 2016-12-07 | 硬木药品公司 | 胃肠疾患的治疗 |
| KR102058864B1 (ko) * | 2013-12-16 | 2019-12-24 | 주식회사 티움바이오 | 인자 vii의 융합 단백질을 포함하는 안정성이 개선된 약학적 조성물 |
| LT3138575T (lt) * | 2014-04-28 | 2021-08-25 | Eisai R&D Management Co., Ltd. | Liofilizuoto hgf paruošimas |
| WO2017159722A1 (fr) | 2016-03-17 | 2017-09-21 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Procédé de production d'un facteur de croissance hépatocytaire (hgf) activé |
| EP3833381B1 (fr) | 2019-08-15 | 2022-08-03 | Catalyst Biosciences, Inc. | Polypeptides de facteur vii modifiés pour une administration sous-cutanée |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9501040D0 (en) * | 1995-01-19 | 1995-03-08 | Quadrant Holdings Cambridge | Dried composition |
| US6017882A (en) * | 1997-10-23 | 2000-01-25 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6693075B1 (en) * | 1997-10-23 | 2004-02-17 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6423826B1 (en) * | 2000-06-30 | 2002-07-23 | Regents Of The University Of Minnesota | High molecular weight derivatives of vitamin K-dependent polypeptides |
| SI1499719T1 (sl) * | 2002-04-30 | 2011-03-31 | Bayer Healthcare Llc | Polipeptidne variante faktorja VII ali VIIa |
| ES2523655T5 (es) * | 2002-06-21 | 2018-04-23 | Novo Nordisk Health Care Ag | Composiciones sólidas estabilizadas de polipéptidos del Factor VIIa |
| US20060166874A1 (en) * | 2002-09-30 | 2006-07-27 | Haaning Jesper M | Fvii or fviia variants having increased clotting activity |
| RU2373953C2 (ru) * | 2003-12-19 | 2009-11-27 | Ново Нордиск Хелс Кеа Аг | Стабилизированная композиция, содержащая полипептид фактора vii |
-
2007
- 2007-12-18 WO PCT/IB2007/004338 patent/WO2008078189A2/fr active Application Filing
- 2007-12-18 CA CA002673260A patent/CA2673260A1/fr not_active Abandoned
- 2007-12-18 EP EP07870424A patent/EP2114379A2/fr not_active Withdrawn
- 2007-12-18 JP JP2009542270A patent/JP2010513462A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008078189A2 (fr) | 2008-07-03 |
| JP2010513462A (ja) | 2010-04-30 |
| WO2008078189A3 (fr) | 2009-03-05 |
| EP2114379A2 (fr) | 2009-11-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| EEER | Examination request |
Effective date: 20121218 |
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| FZDE | Dead |
Effective date: 20151008 |