CA2668487A1 - Erythropoietine derivee des oiseaux - Google Patents

Erythropoietine derivee des oiseaux Download PDF

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Publication number
CA2668487A1
CA2668487A1 CA002668487A CA2668487A CA2668487A1 CA 2668487 A1 CA2668487 A1 CA 2668487A1 CA 002668487 A CA002668487 A CA 002668487A CA 2668487 A CA2668487 A CA 2668487A CA 2668487 A1 CA2668487 A1 CA 2668487A1
Authority
CA
Canada
Prior art keywords
epo
composition
isolated mixture
ifn
glycosylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002668487A
Other languages
English (en)
Inventor
Robert D. Ivarie
Guodong Liu
Jeffrey C. Rapp
Julie A. Morris
Alex J. Harvey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Georgia Research Foundation Inc UGARF
Synageva Biopharma Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2668487A1 publication Critical patent/CA2668487A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne l'érythropoïétine obtenue à partir d'AEufs pondus par des oiseaux transgéniques ayant des motifs de glycosylation liée -N ou liée -O aviaires.
CA002668487A 2006-11-09 2007-10-10 Erythropoietine derivee des oiseaux Abandoned CA2668487A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US85789606P 2006-11-09 2006-11-09
US60/857,896 2006-11-09
US87760106P 2006-12-28 2006-12-28
US60/877,601 2006-12-28
US91850407P 2007-03-16 2007-03-16
US60/918,504 2007-03-16
PCT/US2007/021643 WO2008057161A1 (fr) 2006-11-09 2007-10-10 Érythropoiétine dérivée des oiseaux

Publications (1)

Publication Number Publication Date
CA2668487A1 true CA2668487A1 (fr) 2008-05-15

Family

ID=39364811

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002668487A Abandoned CA2668487A1 (fr) 2006-11-09 2007-10-10 Erythropoietine derivee des oiseaux

Country Status (6)

Country Link
EP (1) EP2076530A4 (fr)
JP (1) JP2010509327A (fr)
KR (1) KR20090090328A (fr)
AU (1) AU2007318209A1 (fr)
CA (1) CA2668487A1 (fr)
WO (1) WO2008057161A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101343485B1 (ko) * 2008-01-07 2013-12-20 시나게바 바이오파르마, 코포레이션 조류에서의 당화
CN102712688B (zh) * 2009-09-23 2015-06-24 通益制药有限公司 重组人红细胞生成素(epo)的纯化方法、由此纯化的epo以及包含纯化的epo的药物组合物
TW201408695A (zh) * 2012-08-30 2014-03-01 Body Organ Biomedical Corp 重組載體及應用其而產生之轉基因魚卵與生物材料
WO2017169978A1 (fr) * 2016-03-31 2017-10-05 株式会社カネカ Procédé de production d'érythropoïétine féline purifiée
US11155794B2 (en) * 2016-08-23 2021-10-26 Alexion Pharmaceuticals, Inc. Method of purifying a heterologous protein from an egg white

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1023442E (pt) * 1997-10-16 2011-02-25 Synageva Biopharma Corp Vectores compreendendo um promotor específico do magno para transgénese aviária
US7129390B2 (en) * 1997-10-16 2006-10-31 Avigenics, Inc Poultry Derived Glycosylated Interferon Alpha 2b
US20040019923A1 (en) * 1997-10-16 2004-01-29 Ivarie Robert D. Exogenous proteins expressed in avians and their eggs
DE69933216T2 (de) * 1998-06-15 2007-09-20 GTC Biotherapeutics, Inc., Framingham Erythropoietin-analog-menschliches serum-albumin fusionsprotein
ATE513038T1 (de) * 2001-09-18 2011-07-15 Synageva Biopharma Corp Produktion eines transgenen vogels mittels cytoplasmainjektion
WO2006112147A1 (fr) * 2005-03-30 2006-10-26 Kaneka Corporation Oiseau transgenique produisant de l’erythropoietine et procede pour l’obtenir

Also Published As

Publication number Publication date
WO2008057161A1 (fr) 2008-05-15
AU2007318209A1 (en) 2008-05-15
EP2076530A1 (fr) 2009-07-08
EP2076530A4 (fr) 2010-04-07
KR20090090328A (ko) 2009-08-25
JP2010509327A (ja) 2010-03-25

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20111011