CA2665839A1 - Polypeptide ligands for targeting cartilage and methods of use thereof - Google Patents
Polypeptide ligands for targeting cartilage and methods of use thereof Download PDFInfo
- Publication number
- CA2665839A1 CA2665839A1 CA002665839A CA2665839A CA2665839A1 CA 2665839 A1 CA2665839 A1 CA 2665839A1 CA 002665839 A CA002665839 A CA 002665839A CA 2665839 A CA2665839 A CA 2665839A CA 2665839 A1 CA2665839 A1 CA 2665839A1
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- Prior art keywords
- polypeptide
- seq
- cartilage
- therapeutic agent
- binding
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US11/545,819 | 2006-10-10 | ||
| US11/545,819 US7592009B2 (en) | 2006-10-10 | 2006-10-10 | Polypeptide ligands for targeting cartilage and methods of use thereof |
| PCT/US2007/021529 WO2008063291A2 (en) | 2006-10-10 | 2007-10-09 | Polypeptide ligands for targeting cartilage and methods of use thereof |
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| CA2665839A1 true CA2665839A1 (en) | 2008-05-29 |
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| JP (1) | JP2010505444A (https=) |
| AU (1) | AU2007322346A1 (https=) |
| CA (1) | CA2665839A1 (https=) |
| IL (1) | IL198120A0 (https=) |
| WO (1) | WO2008063291A2 (https=) |
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| SI2280720T1 (sl) | 2008-03-27 | 2019-06-28 | Purdue Research Foundation | Sintetični peptidoglikani,ki vežejo kolagen, priprava in postopki uporabe |
| US8868149B2 (en) * | 2009-07-30 | 2014-10-21 | Oxitone Medical Ltd. | Photoplethysmography device and method |
| US20120231013A1 (en) | 2009-07-31 | 2012-09-13 | Black Roy A | Polypeptides that bind tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
| WO2017120461A1 (en) | 2016-01-08 | 2017-07-13 | The Board Of Trustees Of The Leland Stanford Junior University | Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same |
| US20160208011A1 (en) | 2010-01-28 | 2016-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same |
| US10487148B2 (en) | 2010-01-28 | 2019-11-26 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for treating aging-associated impairments |
| WO2011097342A1 (en) * | 2010-02-04 | 2011-08-11 | University Of Utah Research Foundation | Hydrophobically-modified hyaluronan and methods of making and using thereof |
| US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
| US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
| US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
| US9173919B2 (en) | 2011-02-16 | 2015-11-03 | Purdue Research Foundation | Collagen-targeted nanoparticles |
| US9161968B2 (en) | 2011-04-08 | 2015-10-20 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists |
| HRP20170482T1 (hr) | 2011-05-24 | 2017-05-19 | Symic Ip, Llc | Sintetski peptidoglikani koji vežu hijaluronsku kiselinu, dobivanje, i postupci uporabe |
| US8623839B2 (en) | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
| CN104870020A (zh) * | 2012-10-19 | 2015-08-26 | 康奈尔大学 | 用于关节软骨的仿生型界面润滑剂 |
| WO2014107566A1 (en) * | 2013-01-04 | 2014-07-10 | Massachusetts Institute Of Technology | Surface binding of nanoparticle based drug delivery to tissue |
| US9200039B2 (en) | 2013-03-15 | 2015-12-01 | Symic Ip, Llc | Extracellular matrix-binding synthetic peptidoglycans |
| WO2015009787A1 (en) | 2013-07-19 | 2015-01-22 | The Johns Hopkins University | Biomaterials comprising hyaluronic acid binding peptides and extracellular matrix binding peptides for hyaluronic acid retention and tissue engineering applications |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| US20170050988A1 (en) * | 2013-11-25 | 2017-02-23 | Sanofi | Dotam derivatives for therapeutic use |
| US10905779B2 (en) | 2013-12-09 | 2021-02-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for screening human blood products comprising plasma using immunocompromised rodent models |
| MX2016007492A (es) | 2013-12-09 | 2017-03-06 | Univ Leland Stanford Junior | Métodos y composiciones para el tratamiento de afecciones asociadas con el envejecimiento. |
| WO2015164822A1 (en) | 2014-04-25 | 2015-10-29 | Purdue Research Foundation | Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction |
| EP3186276B1 (en) | 2014-08-27 | 2019-07-10 | Amgen Inc. | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
| US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
| KR20240025721A (ko) | 2015-06-15 | 2024-02-27 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 노화와 연관된 질환을 치료하기 위한 방법 및 조성물 |
| US11090358B2 (en) | 2015-09-09 | 2021-08-17 | Fred Hutchinson Cancer Research Center | Cartilage-homing peptides |
| ES2900302T3 (es) | 2016-04-28 | 2022-03-16 | Alkahest Inc | Fracciones de plasma como terapia para el crecimiento y la progresión del tumor |
| EA039316B1 (ru) | 2016-10-24 | 2022-01-12 | Алкахест, Инк. | Фракции плазмы крови в качестве лечения когнитивных расстройств, связанных со старением |
| AU2018210157B2 (en) | 2017-01-18 | 2022-10-06 | Fred Hutchinson Cancer Center | Peptide compositions and methods of use thereof for disrupting TEAD interactions |
| EP3595699A4 (en) * | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| WO2018200560A1 (en) | 2017-04-26 | 2018-11-01 | Alkahest, Inc. | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| US11040068B2 (en) | 2017-04-26 | 2021-06-22 | Alkahest, Inc. | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| AU2018283161A1 (en) | 2017-06-15 | 2020-01-02 | Blaze Bioscience, Inc. | Renal-homing peptide conjugates and methods of use thereof |
| WO2019010484A2 (en) | 2017-07-07 | 2019-01-10 | Symic Ip, Llc | SYNTHETIC BIOCONJUGATES |
| EP3727146A4 (en) | 2017-12-19 | 2021-10-06 | Blaze Bioscience, Inc. | TUMOR HOMING AND CELL-PENETANT PEPTIDE IMMUNO-ONCOLOGY AGENT COMPLEX AND METHOD OF USE |
| WO2019178573A1 (en) * | 2018-03-16 | 2019-09-19 | Blaze Bioscience, Inc. | Truncated cartilage-homing peptides and peptide complexes and methods of use thereof |
| WO2020077265A1 (en) | 2018-10-12 | 2020-04-16 | Theradaptive, Inc. | Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof |
| CN119345230A (zh) | 2018-10-26 | 2025-01-24 | 万能溶剂有限公司 | 血浆和血浆组分用于改善疼痛的用途 |
| US20230026969A1 (en) * | 2019-12-03 | 2023-01-26 | China Medical University | Oligopeptide, Testing Kit Thereof And Medical Composition Thereof |
| BR112022020809A2 (pt) | 2020-04-15 | 2023-02-23 | Theradaptive Inc | Composições e métodos para entrega terapêutica direcionada ao osso |
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| US2090925A (en) * | 1935-11-25 | 1937-08-24 | Platt Brothers & Co Ltd | Apparatus for opening and cleaning flax straw and such like fibrous materials |
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| US5185444A (en) * | 1985-03-15 | 1993-02-09 | Anti-Gene Deveopment Group | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages |
| US5227165A (en) * | 1989-11-13 | 1993-07-13 | Nova Pharmaceutical Corporation | Liposphere delivery systems for local anesthetics |
| US5410016A (en) * | 1990-10-15 | 1995-04-25 | Board Of Regents, The University Of Texas System | Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers |
| US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
| US6562596B1 (en) | 1993-10-06 | 2003-05-13 | Amgen Inc. | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
| ATE330644T1 (de) * | 1995-12-18 | 2006-07-15 | Angiotech Biomaterials Corp | Vernetzten polymerisatmassen und verfahren für ihre verwendung |
| CA2267930A1 (en) * | 1996-10-09 | 1998-04-16 | Nobuyuki Takechi | A method for producing a microparticle |
| US6224794B1 (en) * | 1998-05-06 | 2001-05-01 | Angiotech Pharmaceuticals, Inc. | Methods for microsphere production |
| US20090087878A9 (en) * | 1999-05-06 | 2009-04-02 | La Rosa Thomas J | Nucleic acid molecules associated with plants |
| WO2001044497A2 (en) * | 1999-12-02 | 2001-06-21 | University Of Dundee | Protein kinase regulation |
| US20110131679A2 (en) * | 2000-04-19 | 2011-06-02 | Thomas La Rosa | Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
| CA2407352A1 (en) * | 2000-04-21 | 2001-11-01 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of acne vulgaris |
| US7630836B2 (en) * | 2001-05-30 | 2009-12-08 | The Kitasato Institute | Polynucleotides |
| US7314974B2 (en) * | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
| AU2003301619A1 (en) * | 2002-10-23 | 2004-05-13 | Exelixis, Inc. | MBMs AS MODIFIERS OF BRANCHING MORPHOGENESIS AND METHODS OF USE |
-
2006
- 2006-10-10 US US11/545,819 patent/US7592009B2/en active Active
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2007
- 2007-10-09 WO PCT/US2007/021529 patent/WO2008063291A2/en not_active Ceased
- 2007-10-09 EP EP07870773A patent/EP2084275A4/en active Pending
- 2007-10-09 JP JP2009532369A patent/JP2010505444A/ja active Pending
- 2007-10-09 CA CA002665839A patent/CA2665839A1/en not_active Abandoned
- 2007-10-09 AU AU2007322346A patent/AU2007322346A1/en not_active Abandoned
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2009
- 2009-04-07 IL IL198120A patent/IL198120A0/en unknown
- 2009-09-21 US US12/563,201 patent/US20100080850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2084275A4 (en) | 2012-01-04 |
| WO2008063291A2 (en) | 2008-05-29 |
| AU2007322346A1 (en) | 2008-05-29 |
| IL198120A0 (en) | 2011-08-01 |
| US7592009B2 (en) | 2009-09-22 |
| JP2010505444A (ja) | 2010-02-25 |
| US20080118523A1 (en) | 2008-05-22 |
| US20100080850A1 (en) | 2010-04-01 |
| WO2008063291A3 (en) | 2008-10-02 |
| EP2084275A2 (en) | 2009-08-05 |
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