CA2663300C - Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1 - Google Patents
Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1 Download PDFInfo
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- CA2663300C CA2663300C CA2663300A CA2663300A CA2663300C CA 2663300 C CA2663300 C CA 2663300C CA 2663300 A CA2663300 A CA 2663300A CA 2663300 A CA2663300 A CA 2663300A CA 2663300 C CA2663300 C CA 2663300C
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06019362.0 | 2006-09-15 | ||
| EP06019362 | 2006-09-15 | ||
| US90477607P | 2007-03-05 | 2007-03-05 | |
| US60/904,776 | 2007-03-05 | ||
| PCT/EP2007/008029 WO2008031612A1 (en) | 2006-09-15 | 2007-09-14 | Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1 |
Publications (2)
| Publication Number | Publication Date |
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| CA2663300A1 CA2663300A1 (en) | 2008-03-20 |
| CA2663300C true CA2663300C (en) | 2014-10-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2663300A Expired - Fee Related CA2663300C (en) | 2006-09-15 | 2007-09-14 | Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1 |
Country Status (10)
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Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20110017371A (ko) | 2008-04-30 | 2011-02-21 | 가부시키가이샤 제노믹스 | 생체내 기능적 세포의 고효율 채취법 |
| US20120165244A1 (en) * | 2008-10-30 | 2012-06-28 | Hua-Lin Wu | Methods for binding lewis y antigen |
| CN101691580B (zh) * | 2009-09-28 | 2012-02-15 | 中国人民解放军第三军医大学 | 人HMGB1 A box和酸性尾端的新型融合蛋白及其应用 |
| JP5467313B2 (ja) * | 2009-09-28 | 2014-04-09 | 国立大学法人 岡山大学 | アテローム動脈硬化抑制剤 |
| KR20120135190A (ko) | 2009-10-28 | 2012-12-12 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제 |
| US20110123483A1 (en) * | 2009-11-23 | 2011-05-26 | Deutsches Krebsforschungszentrum | Hmgb1 for cancer treatment |
| US8981025B2 (en) | 2011-02-10 | 2015-03-17 | Corning Incorporated | Polymerizable catonic peptide monomers and polymers |
| KR102113809B1 (ko) | 2011-04-26 | 2020-05-21 | 가부시키가이샤 스템림 | 조직 재생을 유도하기 위한 펩티드 및 그의 이용 |
| ES2661500T3 (es) | 2012-07-26 | 2018-04-02 | Ospedale San Raffaele S.R.L. | Variantes de HMGB1 y sus usos |
| GB201508337D0 (en) | 2015-05-15 | 2015-06-24 | Hmgbiotech S R L | Novel peptides |
| JP7107839B2 (ja) | 2015-12-11 | 2022-07-27 | ルプレヒト－カールス－ウニベルジテート ハイデルベルク | Ｐｋｍ２モジュレーター及びｈｍｇｂ１の組合せ製剤 |
| PL3556378T3 (pl) | 2017-01-27 | 2025-06-09 | StemRIM Inc. | Środek do leczenia kardiomiopatii, starego zawału mięśnia sercowego i przewlekłej niewydolności serca |
| US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
| CN118460462A (zh) | 2017-12-01 | 2024-08-09 | 斯特姆里姆有限公司 | 外胚层间充质干细胞及其产生方法 |
| WO2019156137A1 (ja) | 2018-02-08 | 2019-08-15 | 株式会社ステムリム | 乾癬の治療薬 |
| WO2020072993A1 (en) * | 2018-10-05 | 2020-04-09 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms cross-reference to related application |
| US12304933B2 (en) | 2018-10-05 | 2025-05-20 | StemRIM Inc. | Disease treatment drug based on mesenchymal-stem-cell mobilization |
| JP7448126B2 (ja) * | 2018-10-25 | 2024-03-12 | 国立大学法人大阪大学 | 軟骨疾患の治療薬 |
| US11684653B2 (en) * | 2019-03-06 | 2023-06-27 | The Cleveland Clinic Foundation | Compositions and method for reducing virulence of microorganisms |
| CA3164781A1 (en) | 2019-12-18 | 2021-06-24 | F. Hoffmann-La Roche Ag | Methods of sequencing by synthesis using a consecutive labeling scheme |
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| DE3676670D1 (de) * | 1985-06-26 | 1991-02-07 | Cetus Corp | Solubilisierung von proteinen fuer pharmazeutische zusammensetzungen mittels polymerkonjugierung. |
| DK1656952T3 (da) * | 1998-10-16 | 2014-01-20 | Biogen Idec Inc | Polyalkylenglycolkonjugater af interferon beta-1A og anvendelser deraf |
| TR200301208T2 (tr) | 2001-02-01 | 2005-05-23 | Biogen, Inc. | Nublastin polimer eşlenikleri ve bunları kullanma yöntemleri. |
| US7754217B2 (en) | 2001-03-16 | 2010-07-13 | Bio3 Research Srl | HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases |
| BR0209689A (pt) * | 2001-05-15 | 2006-02-07 | Long Island Jewish Res Inst | Uso de fragmento de hmg como agente anti-inflamatório |
| WO2004046345A2 (en) | 2002-11-20 | 2004-06-03 | Critical Therapeutics, Inc. | Use of hmgb fragments as anti-inflammatory agents |
| MXPA05006688A (es) | 2002-12-19 | 2006-02-22 | Nektar Therapeutics Al Corp | Conjugados de polimero con una variante de cianovirina. |
| TW200510454A (en) | 2003-04-15 | 2005-03-16 | Smithkline Beecham Corp | Conjugates comprising human IL-18 and substitution mutants thereof |
| AU2005319099B2 (en) | 2004-02-02 | 2010-09-16 | Ambrx, Inc. | Modified human growth hormone |
| EP1814576A2 (en) * | 2004-07-20 | 2007-08-08 | Critical Therapeutics, Inc. | Combination therapies of hmgb and complement inhibitors against inflammation |
| AU2005279308B2 (en) * | 2004-09-03 | 2012-05-03 | Creabilis Therapeutics S.R.L. | Protease resistant human and non-human HMGB1 Box-A mutants and their therapeutic/diagnostic use |
| HRP20140218T4 (hr) | 2005-08-25 | 2017-06-16 | Creabilis Therapeutics S.P.A. | Polimerni konjugati k-252a i njihovi derivati |
-
2007
- 2007-09-14 HR HR20110487T patent/HRP20110487T1/hr unknown
- 2007-09-14 US US12/441,478 patent/US8546547B2/en not_active Expired - Fee Related
- 2007-09-14 AU AU2007296843A patent/AU2007296843C1/en not_active Ceased
- 2007-09-14 WO PCT/EP2007/008029 patent/WO2008031612A1/en not_active Ceased
- 2007-09-14 JP JP2009527748A patent/JP2010503630A/ja active Pending
- 2007-09-14 CA CA2663300A patent/CA2663300C/en not_active Expired - Fee Related
- 2007-09-14 PL PL07818168T patent/PL2068935T3/pl unknown
- 2007-09-14 MX MX2009002820A patent/MX2009002820A/es active IP Right Grant
- 2007-09-14 EP EP07818168A patent/EP2068935B8/en not_active Revoked
-
2009
- 2009-03-05 IL IL197441A patent/IL197441A/en active IP Right Grant
-
2012
- 2012-12-27 US US13/728,455 patent/US9707298B2/en not_active Expired - Fee Related
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2015
- 2015-07-13 JP JP2015139496A patent/JP2015193646A/ja active Pending
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2017
- 2017-04-28 US US15/581,358 patent/US20170304398A1/en not_active Abandoned
- 2017-06-08 JP JP2017113232A patent/JP2017200930A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2068935A1 (en) | 2009-06-17 |
| US9707298B2 (en) | 2017-07-18 |
| US8546547B2 (en) | 2013-10-01 |
| IL197441A (en) | 2013-07-31 |
| US20170304398A1 (en) | 2017-10-26 |
| MX2009002820A (es) | 2009-06-04 |
| JP2015193646A (ja) | 2015-11-05 |
| JP2017200930A (ja) | 2017-11-09 |
| PL2068935T3 (pl) | 2011-11-30 |
| HK1134779A1 (en) | 2010-05-14 |
| JP2010503630A (ja) | 2010-02-04 |
| IL197441A0 (en) | 2009-12-24 |
| WO2008031612A1 (en) | 2008-03-20 |
| AU2007296843A1 (en) | 2008-03-20 |
| CA2663300A1 (en) | 2008-03-20 |
| US20090324677A1 (en) | 2009-12-31 |
| HRP20110487T1 (hr) | 2011-08-31 |
| US20140065094A1 (en) | 2014-03-06 |
| AU2007296843C1 (en) | 2012-08-16 |
| EP2068935B8 (en) | 2011-09-14 |
| AU2007296843B2 (en) | 2012-02-23 |
| EP2068935B1 (en) | 2011-04-13 |
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