CA2659909A1 - Treatment for chronic progressive heart failure - Google Patents
Treatment for chronic progressive heart failure Download PDFInfo
- Publication number
- CA2659909A1 CA2659909A1 CA002659909A CA2659909A CA2659909A1 CA 2659909 A1 CA2659909 A1 CA 2659909A1 CA 002659909 A CA002659909 A CA 002659909A CA 2659909 A CA2659909 A CA 2659909A CA 2659909 A1 CA2659909 A1 CA 2659909A1
- Authority
- CA
- Canada
- Prior art keywords
- poloxamer
- heart failure
- patient
- heart
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83472806P | 2006-08-01 | 2006-08-01 | |
| US60/834,728 | 2006-08-01 | ||
| PCT/US2007/017182 WO2008016640A2 (en) | 2006-08-01 | 2007-08-01 | Use of poloxamer for the prevention and/or treatment of heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2659909A1 true CA2659909A1 (en) | 2008-02-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002659909A Abandoned CA2659909A1 (en) | 2006-08-01 | 2007-08-01 | Treatment for chronic progressive heart failure |
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| Country | Link |
|---|---|
| US (1) | US9155758B2 (https=) |
| EP (1) | EP2046348B1 (https=) |
| JP (2) | JP5537152B2 (https=) |
| CN (4) | CN103222984A (https=) |
| AU (1) | AU2007281531B2 (https=) |
| CA (1) | CA2659909A1 (https=) |
| WO (1) | WO2008016640A2 (https=) |
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| EP2046348B1 (en) | 2006-08-01 | 2015-07-22 | Phrixus Pharmaceuticals, Incorporated | Use of poloxamer for the prevention and/or treatment of heart failure |
| WO2008124088A2 (en) * | 2007-04-05 | 2008-10-16 | Phrixus Pharmaceuticals, Inc. | Compositions and methods for the treatment of heart failure |
| US20130143804A1 (en) * | 2010-06-07 | 2013-06-06 | Trustees Of The University Of Pennsylvania | Islet Amyloid Polypeptide Toxic Oligomer is a Biomarker of Heart or Kidney Failure in Type-2 Diabetes Mellitus |
| EP3057598A1 (en) * | 2013-10-16 | 2016-08-24 | Mast Therapeutics, Inc. | Diuretic induced alterations of plasma volume |
| US9757411B2 (en) | 2014-07-07 | 2017-09-12 | Aires Pharmaceuticals, Inc. | Poloxamer therapy for heart failure |
| JP6747748B2 (ja) | 2014-07-07 | 2020-08-26 | ライフラフト バイオサイエンシーズ，インコーポレイテッド | 長期循環物質のないポロクサマー組成物、その産生方法およびその使用 |
| WO2016007542A1 (en) * | 2014-07-07 | 2016-01-14 | Mast Therapeutics, Inc. | Poloxamer therapy for heart failure |
| US20230190676A1 (en) * | 2020-07-09 | 2023-06-22 | Musc Foundation For Research Development | Methods of protecting cells from insults |
| CN111973623B (zh) * | 2020-08-06 | 2022-04-05 | 温州医科大学 | 心力衰竭靶向治疗的速释制剂 |
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| US5198211A (en) | 1986-05-15 | 1993-03-30 | Emory University | Method of treating myocardial damage |
| US5733572A (en) | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
| ES2140408T3 (es) | 1991-03-19 | 2000-03-01 | Cytrx Corp | Copolimeros de polioxipropileno/polioxietileno con actividad biologica mejorada. |
| JPH05178760A (ja) | 1991-06-03 | 1993-07-20 | Alpha Therapeutic Corp | 心筋梗塞治療剤 |
| US5605687A (en) | 1992-05-15 | 1997-02-25 | Arch Development Corporation | Methods and compositions of a polymer (poloxamer) for repair of electrical injury |
| US5994348A (en) | 1995-06-07 | 1999-11-30 | Sanofi | Pharmaceutical compositions containing irbesartan |
| WO2000021543A1 (en) | 1998-10-09 | 2000-04-20 | Cytrx Corporation | Method and composition for treating ischemia and sickle cell anemia |
| US20020013331A1 (en) | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
| US6761824B2 (en) | 2000-08-17 | 2004-07-13 | Reeve Lorraine E | Process for the fractionation of polymers |
| WO2002065834A2 (en) | 2000-10-24 | 2002-08-29 | Smithkline Beecham Corporation | Novel formulations of carvedilol |
| WO2003078603A2 (en) | 2002-03-15 | 2003-09-25 | Board Of Regents, The University Of Texas System | Strong gene sets for glioma classification |
| US7550155B2 (en) | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
| AU2005289520A1 (en) | 2004-09-27 | 2006-04-06 | Vical Incorporated | Formulations and methods for treatment of inflammatory diseases |
| EP1809272A4 (en) | 2004-10-18 | 2008-01-02 | Maroon Biotech Corp | METHOD AND COMPOSITIONS FOR TREATING DAMAGES THROUGH FREE RADICALS |
| CA2599219C (en) * | 2005-02-25 | 2011-09-20 | The Regents Of The University Of Michigan | Compositions and methods for treating and preventing cardiomyopathy and heart disease |
| DE602006014514D1 (https=) | 2005-03-21 | 2010-07-08 | Santhera Pharmaceuticals Ch | |
| NZ569396A (en) | 2006-02-03 | 2011-06-30 | Nicox Sa | Use of nitrooxyderivative of drug for the treatment of muscular dystrophies |
| EP2046348B1 (en) | 2006-08-01 | 2015-07-22 | Phrixus Pharmaceuticals, Incorporated | Use of poloxamer for the prevention and/or treatment of heart failure |
| WO2008124088A2 (en) | 2007-04-05 | 2008-10-16 | Phrixus Pharmaceuticals, Inc. | Compositions and methods for the treatment of heart failure |
| WO2009078978A2 (en) | 2007-12-14 | 2009-06-25 | Phrixus Pharmaceuticals, Inc. | Compositions containing polyglycidol-based polymers and uses thereof |
| US8852568B2 (en) | 2007-12-17 | 2014-10-07 | The Regents Of The University Of Michigan | Compositions and methods for treating and preventing skeletal muscle deficiencies |
| WO2011066201A2 (en) | 2009-11-25 | 2011-06-03 | The Regents Of The University Of Michigan | Methods and systems for treating and preventing cardiac injury in dystrophic subjects |
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- 2007-08-01 CN CN2013100791323A patent/CN103222984A/zh active Pending
- 2007-08-01 WO PCT/US2007/017182 patent/WO2008016640A2/en not_active Ceased
- 2007-08-01 US US12/309,803 patent/US9155758B2/en not_active Expired - Fee Related
- 2007-08-01 AU AU2007281531A patent/AU2007281531B2/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| US20090246162A1 (en) | 2009-10-01 |
| CN102218077A (zh) | 2011-10-19 |
| EP2046348B1 (en) | 2015-07-22 |
| WO2008016640A2 (en) | 2008-02-07 |
| CN101534843A (zh) | 2009-09-16 |
| CN103222984A (zh) | 2013-07-31 |
| JP5537152B2 (ja) | 2014-07-02 |
| JP2013253103A (ja) | 2013-12-19 |
| JP2009545595A (ja) | 2009-12-24 |
| CN103271935A (zh) | 2013-09-04 |
| EP2046348A2 (en) | 2009-04-15 |
| AU2007281531A1 (en) | 2008-02-07 |
| AU2007281531B2 (en) | 2013-07-04 |
| US9155758B2 (en) | 2015-10-13 |
| WO2008016640A3 (en) | 2009-02-05 |
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