CA2659909A1 - Treatment for chronic progressive heart failure - Google Patents
Treatment for chronic progressive heart failure Download PDFInfo
- Publication number
- CA2659909A1 CA2659909A1 CA002659909A CA2659909A CA2659909A1 CA 2659909 A1 CA2659909 A1 CA 2659909A1 CA 002659909 A CA002659909 A CA 002659909A CA 2659909 A CA2659909 A CA 2659909A CA 2659909 A1 CA2659909 A1 CA 2659909A1
- Authority
- CA
- Canada
- Prior art keywords
- poloxamer
- heart failure
- patient
- heart
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
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- Medicinal Chemistry (AREA)
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- Organic Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US83472806P | 2006-08-01 | 2006-08-01 | |
| US60/834,728 | 2006-08-01 | ||
| PCT/US2007/017182 WO2008016640A2 (en) | 2006-08-01 | 2007-08-01 | Use of poloxamer for the prevention and/or treatment of heart failure |
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| CA2659909A1 true CA2659909A1 (en) | 2008-02-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA002659909A Abandoned CA2659909A1 (en) | 2006-08-01 | 2007-08-01 | Treatment for chronic progressive heart failure |
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| EP (1) | EP2046348B1 (cg-RX-API-DMAC10.html) |
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| CA (1) | CA2659909A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2008016640A2 (cg-RX-API-DMAC10.html) |
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| CN101534843A (zh) | 2006-08-01 | 2009-09-16 | 普里克萨斯医药股份有限公司 | 泊洛沙姆用于预防和/或治疗心力衰竭的用途 |
| WO2008124088A2 (en) * | 2007-04-05 | 2008-10-16 | Phrixus Pharmaceuticals, Inc. | Compositions and methods for the treatment of heart failure |
| WO2011156389A2 (en) * | 2010-06-07 | 2011-12-15 | The Regents Of The University Of California | The islet amyloid polypeptide toxic oligomer is a biomarker of heart or kidney failure in type-2 diabetes mellitus |
| JP2016533377A (ja) * | 2013-10-16 | 2016-10-27 | マスト セラピューティクス インコーポレイテッドＭａｓｔ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 利尿薬によって誘発される血漿量の変化 |
| AU2015287993B2 (en) | 2014-07-07 | 2020-10-29 | Liferaft Biosciences, Inc. | A poloxamer composition free of long circulating material and methods for production and uses thereof |
| US9757411B2 (en) | 2014-07-07 | 2017-09-12 | Aires Pharmaceuticals, Inc. | Poloxamer therapy for heart failure |
| WO2016007542A1 (en) * | 2014-07-07 | 2016-01-14 | Mast Therapeutics, Inc. | Poloxamer therapy for heart failure |
| JP7867990B2 (ja) * | 2020-07-09 | 2026-06-01 | ムスク・ファウンデイション・フォー・リサーチ・ディベロップメント | 傷害から細胞を保護する方法 |
| CN111973623B (zh) * | 2020-08-06 | 2022-04-05 | 温州医科大学 | 心力衰竭靶向治疗的速释制剂 |
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| US5198211A (en) | 1986-05-15 | 1993-03-30 | Emory University | Method of treating myocardial damage |
| US5733572A (en) | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
| EP0576612B1 (en) | 1991-03-19 | 1999-12-01 | Cytrx Corporation | Polyoxypropylene/polyoxyethylene copolymers with improved biological activity |
| WO1992022202A1 (en) | 1991-06-03 | 1992-12-23 | Alpha Therapeutics Corporation | Thrombolytic and perfluorochemical treatment for myocardial infraction |
| US5605687A (en) | 1992-05-15 | 1997-02-25 | Arch Development Corporation | Methods and compositions of a polymer (poloxamer) for repair of electrical injury |
| US5994348A (en) | 1995-06-07 | 1999-11-30 | Sanofi | Pharmaceutical compositions containing irbesartan |
| AU1312800A (en) | 1998-10-09 | 2000-05-01 | Cytrx Corporation | Method and composition for treating ischemia and sickle cell anemia |
| US20020013331A1 (en) | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
| US6761824B2 (en) | 2000-08-17 | 2004-07-13 | Reeve Lorraine E | Process for the fractionation of polymers |
| EP1335707A4 (en) | 2000-10-24 | 2005-07-06 | Smithkline Beecham Corp | NEW CARVEDILOL FORMULATIONS |
| US7341552B2 (en) | 2002-03-15 | 2008-03-11 | The University Of Texas System Board Of Regents | Gene sets for glioma classification |
| US7550155B2 (en) | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
| WO2006037031A2 (en) | 2004-09-27 | 2006-04-06 | Valentis, Inc. | Formulations and methods for treatment of inflammatory diseases |
| US20060121016A1 (en) | 2004-10-18 | 2006-06-08 | Lee Raphael C | Methods and compositions for treatment of free radical injury |
| EP1853280B1 (en) | 2005-02-25 | 2012-02-22 | The Regents Of The University Of Michigan | Compositions and methods for treating and preventing cardiomyopathy and heart disease |
| PL1861080T3 (pl) | 2005-03-21 | 2010-10-29 | Santhera Pharmaceuticals Schweiz Ag | Idebenon do leczenia dystrofii mięśniowych |
| JP5745210B2 (ja) | 2006-02-03 | 2015-07-08 | ニコックス サイエンス アイルランド | 筋ジストロフィーの治療用薬剤のニトロオキシ誘導体の使用 |
| CN101534843A (zh) | 2006-08-01 | 2009-09-16 | 普里克萨斯医药股份有限公司 | 泊洛沙姆用于预防和/或治疗心力衰竭的用途 |
| WO2008124088A2 (en) | 2007-04-05 | 2008-10-16 | Phrixus Pharmaceuticals, Inc. | Compositions and methods for the treatment of heart failure |
| WO2009078978A2 (en) | 2007-12-14 | 2009-06-25 | Phrixus Pharmaceuticals, Inc. | Compositions containing polyglycidol-based polymers and uses thereof |
| EP2234625B8 (en) | 2007-12-17 | 2013-10-30 | The Regents of the University of Michigan | Compositions and methods for treating and preventing skeletal muscle deficiencies |
| WO2011066201A2 (en) | 2009-11-25 | 2011-06-03 | The Regents Of The University Of Michigan | Methods and systems for treating and preventing cardiac injury in dystrophic subjects |
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| EP2046348B1 (en) | 2015-07-22 |
| CN103222984A (zh) | 2013-07-31 |
| WO2008016640A2 (en) | 2008-02-07 |
| CN101534843A (zh) | 2009-09-16 |
| AU2007281531A1 (en) | 2008-02-07 |
| JP2013253103A (ja) | 2013-12-19 |
| CN103271935A (zh) | 2013-09-04 |
| WO2008016640A3 (en) | 2009-02-05 |
| CN102218077A (zh) | 2011-10-19 |
| JP5537152B2 (ja) | 2014-07-02 |
| US9155758B2 (en) | 2015-10-13 |
| EP2046348A2 (en) | 2009-04-15 |
| AU2007281531B2 (en) | 2013-07-04 |
| JP2009545595A (ja) | 2009-12-24 |
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