CA2658305C - Transcription infidelity, detection and uses thereof - Google Patents

Transcription infidelity, detection and uses thereof Download PDF

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Publication number
CA2658305C
CA2658305C CA2658305A CA2658305A CA2658305C CA 2658305 C CA2658305 C CA 2658305C CA 2658305 A CA2658305 A CA 2658305A CA 2658305 A CA2658305 A CA 2658305A CA 2658305 C CA2658305 C CA 2658305C
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CA
Canada
Prior art keywords
protein
sequence
transcription infidelity
cancer
transcription
Prior art date
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CA2658305A
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English (en)
French (fr)
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CA2658305A1 (en
Inventor
Bernard Bihain
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Transmedi SA
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Transmedi SA
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Glass Compositions (AREA)
  • Pit Excavations, Shoring, Fill Or Stabilisation Of Slopes (AREA)
  • Peptides Or Proteins (AREA)
CA2658305A 2006-07-20 2007-07-20 Transcription infidelity, detection and uses thereof Active CA2658305C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06291176A EP1887088A1 (en) 2006-07-20 2006-07-20 Transcription infidelity, detection and uses thereof
EP06291176.3 2006-07-20
PCT/EP2007/057541 WO2008009751A2 (en) 2006-07-20 2007-07-20 Transcription infidelity, detection and uses thereof

Publications (2)

Publication Number Publication Date
CA2658305A1 CA2658305A1 (en) 2008-01-24
CA2658305C true CA2658305C (en) 2017-07-18

Family

ID=37496681

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2658305A Active CA2658305C (en) 2006-07-20 2007-07-20 Transcription infidelity, detection and uses thereof

Country Status (18)

Country Link
US (1) US8288091B2 (enExample)
EP (3) EP1887088A1 (enExample)
JP (1) JP5298013B2 (enExample)
KR (1) KR101502179B1 (enExample)
AT (1) ATE524565T1 (enExample)
AU (1) AU2007275068B2 (enExample)
BR (1) BRPI0714563B8 (enExample)
CA (1) CA2658305C (enExample)
CY (2) CY1112125T1 (enExample)
DK (2) DK2468885T3 (enExample)
ES (2) ES2553435T3 (enExample)
HU (1) HUE028135T2 (enExample)
IL (1) IL196600A0 (enExample)
PL (2) PL2468885T3 (enExample)
PT (2) PT2468885E (enExample)
SI (2) SI2468885T1 (enExample)
TR (1) TR201112295Y (enExample)
WO (1) WO2008009751A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2071334A1 (en) * 2007-12-14 2009-06-17 Transmedi SA Compositions and methods of detecting TIABS
EP2080812A1 (en) 2008-01-18 2009-07-22 Transmedi SA Compositions and methods of detecting post-stop peptides
EP2995688A1 (en) 2014-09-12 2016-03-16 Genclis Methods of prognosing and treating triple negative breast cancer
WO2017100789A1 (en) * 2015-12-11 2017-06-15 Expression Pathology, Inc. Srm/mrm assays
EP4148427A1 (en) 2016-03-18 2023-03-15 Genclis Molecular origin of allergy
WO2018187216A1 (en) * 2017-04-03 2018-10-11 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Expression cassettes and methods for detecting transcription errors
WO2019084158A1 (en) 2017-10-26 2019-05-02 Ultima Genomics, Inc. METHODS AND SYSTEMS FOR SEQUENCE CALL
WO2020185790A1 (en) 2019-03-10 2020-09-17 Ultima Genomics, Inc. Methods and systems for sequence calling
EP4010481A4 (en) 2019-08-09 2023-09-20 Nutcracker Therapeutics, Inc. MICROFLUIDIC DEVICE AND METHODS OF USE
KR102334576B1 (ko) * 2019-08-12 2021-12-07 한국생명공학연구원 융합 단백질 및 이를 포함하는 바이오 이미징용 조성물
EP4211268A4 (en) * 2020-09-10 2024-09-18 Ultima Genomics, Inc. SEQUENCE AND VARIANT CALLING METHODS AND SYSTEMS
WO2022108309A1 (ko) * 2020-11-18 2022-05-27 한양대학교 에리카산학협력단 인산화된 비멘틴의 과도한 생성을 차단하여 암을 예방 또는 치료하는 방법
EP4162948A1 (en) 2021-10-05 2023-04-12 Genclis Transcription infidelity derived chimeric immunogens and uses thereof
WO2023104904A2 (en) 2021-12-08 2023-06-15 Genclis The sars-cov-2 and variants use two independent cell receptors to replicate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4979330A (en) 1989-10-10 1990-12-25 Rorant Julius W Suction insect trap device
US6120992A (en) 1993-11-04 2000-09-19 Valigene Corporation Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, and allele identification in a diseased human
AU2715601A (en) * 1999-12-03 2001-06-12 Koninklijke Nederlandse Akademie Van Wetenschappen Clearance of aberrant protein in correlation with disease
WO2002077286A1 (en) 2001-02-21 2002-10-03 Gene Check, Inc. Mutation detection using muts and reca
WO2006053061A2 (en) * 2004-11-10 2006-05-18 Kansas State University Research Foundation Porcine reproductive and respiratory syndrome virus receptor components and uses thereof

Also Published As

Publication number Publication date
EP2468885A2 (en) 2012-06-27
KR20090052861A (ko) 2009-05-26
EP2046986A2 (en) 2009-04-15
DK2046986T3 (da) 2012-01-02
ES2373428T3 (es) 2012-02-03
CY1112125T1 (el) 2015-11-04
BRPI0714563B8 (pt) 2021-05-25
AU2007275068B2 (en) 2013-06-06
EP2046986B1 (en) 2011-09-14
PT2468885E (pt) 2015-11-26
SI2046986T1 (sl) 2012-05-31
EP2468885B1 (en) 2015-08-19
WO2008009751A2 (en) 2008-01-24
CA2658305A1 (en) 2008-01-24
US20090317386A1 (en) 2009-12-24
US8288091B2 (en) 2012-10-16
PT2046986E (pt) 2011-12-29
SI2468885T1 (sl) 2016-02-29
PL2046986T3 (pl) 2012-02-29
DK2468885T3 (da) 2016-02-29
PL2468885T3 (pl) 2016-04-29
IL196600A0 (en) 2009-11-18
HK1128937A1 (en) 2009-11-13
JP2009544284A (ja) 2009-12-17
ATE524565T1 (de) 2011-09-15
JP5298013B2 (ja) 2013-09-25
EP2468885A3 (en) 2012-08-29
BRPI0714563B1 (pt) 2019-07-02
BRPI0714563A2 (pt) 2015-04-14
TR201112295Y (tr) 2018-08-27
EP1887088A1 (en) 2008-02-13
CY1116939T1 (el) 2017-04-05
HUE028135T2 (en) 2016-12-28
ES2553435T3 (es) 2015-12-09
KR101502179B1 (ko) 2015-03-12
WO2008009751A3 (en) 2008-07-31
AU2007275068A1 (en) 2008-01-24

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