CA2654927A1 - Substituted phenyl acetic acids as dp-2 antagonists - Google Patents

Substituted phenyl acetic acids as dp-2 antagonists Download PDF

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Publication number
CA2654927A1
CA2654927A1 CA002654927A CA2654927A CA2654927A1 CA 2654927 A1 CA2654927 A1 CA 2654927A1 CA 002654927 A CA002654927 A CA 002654927A CA 2654927 A CA2654927 A CA 2654927A CA 2654927 A1 CA2654927 A1 CA 2654927A1
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CA
Canada
Prior art keywords
phenyl
acetic acid
piperidin
compound
fluorophenylsulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002654927A
Other languages
English (en)
French (fr)
Inventor
Thomas Dudler
Francine Farouz
Kerry Fowler
Nataly Hawthorn
Danwen Huang
Jin Bohan
Musong Kim
Andrew Lover
Joshua Odingo
Amy Oliver
Mark Reed
Fuqiang Ruan
Eugene Thorsett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Icos Corp
Original Assignee
Icos Corporation
Thomas Dudler
Francine Farouz
Kerry Fowler
Nataly Hawthorn
Danwen Huang
Jin Bohan
Musong Kim
Andrew Lover
Joshua Odingo
Amy Oliver
Mark Reed
Fuqiang Ruan
Eugene Thorsett
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corporation, Thomas Dudler, Francine Farouz, Kerry Fowler, Nataly Hawthorn, Danwen Huang, Jin Bohan, Musong Kim, Andrew Lover, Joshua Odingo, Amy Oliver, Mark Reed, Fuqiang Ruan, Eugene Thorsett filed Critical Icos Corporation
Publication of CA2654927A1 publication Critical patent/CA2654927A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
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    • C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
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    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • AIDS & HIV (AREA)
CA002654927A 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists Abandoned CA2654927A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81239906P 2006-06-09 2006-06-09
US60/812,399 2006-06-09
PCT/US2007/070805 WO2007146838A2 (en) 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists

Publications (1)

Publication Number Publication Date
CA2654927A1 true CA2654927A1 (en) 2007-12-21

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CA002654927A Abandoned CA2654927A1 (en) 2006-06-09 2007-06-08 Substituted phenyl acetic acids as dp-2 antagonists

Country Status (10)

Country Link
EP (1) EP2044017A2 (pt)
JP (1) JP2009539881A (pt)
CN (1) CN101490001A (pt)
AU (1) AU2007257841A1 (pt)
BR (1) BRPI0712332A2 (pt)
CA (1) CA2654927A1 (pt)
EA (2) EA200802417A1 (pt)
MX (1) MX2008015638A (pt)
NO (1) NO20090139L (pt)
WO (1) WO2007146838A2 (pt)

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MX2010004309A (es) 2007-10-19 2010-05-03 Janssen Pharmaceutica Nv Moduladores de piperidinil y piperazinil de gamma-secretasa.
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PT3409278T (pt) 2011-07-21 2020-12-18 Sumitomo Dainippon Pharma Oncology Inc Inibidores de proteína cinase heterocíclicos
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NO20090139L (no) 2009-03-05
EP2044017A2 (en) 2009-04-08
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EA201200423A1 (ru) 2012-08-30
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AU2007257841A1 (en) 2007-12-21

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