CA2652087A1 - A method for predicting responsiveness to tnf.alpha. blocking agents - Google Patents
A method for predicting responsiveness to tnf.alpha. blocking agents Download PDFInfo
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- CA2652087A1 CA2652087A1 CA002652087A CA2652087A CA2652087A1 CA 2652087 A1 CA2652087 A1 CA 2652087A1 CA 002652087 A CA002652087 A CA 002652087A CA 2652087 A CA2652087 A CA 2652087A CA 2652087 A1 CA2652087 A1 CA 2652087A1
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP06290789.4 | 2006-05-16 | ||
| EP06290789A EP1857559A1 (de) | 2006-05-16 | 2006-05-16 | Verfahren zur Vorhersage der Sensivität gegenüber TNF-alpha-Blockern |
| PCT/IB2007/002373 WO2007135568A2 (en) | 2006-05-16 | 2007-05-15 | A METHOD FOR PREDICTING RESPONSIVENESS TO TNFα BLOCKING AGENTS |
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| CA2652087A1 true CA2652087A1 (en) | 2007-11-29 |
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| CA002652087A Abandoned CA2652087A1 (en) | 2006-05-16 | 2007-05-15 | A method for predicting responsiveness to tnf.alpha. blocking agents |
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| US (1) | US7985549B2 (de) |
| EP (2) | EP1857559A1 (de) |
| AT (1) | ATE530670T1 (de) |
| CA (1) | CA2652087A1 (de) |
| DK (1) | DK2019872T3 (de) |
| ES (1) | ES2375865T3 (de) |
| WO (1) | WO2007135568A2 (de) |
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| EA017815B1 (ru) * | 2007-06-08 | 2013-03-29 | Байоджен Айдек Ма Инк. | Биомаркеры для прогнозирования чувствительности или отсутствия чувствительности к анти-фно агентам |
| WO2009117791A2 (en) * | 2008-03-28 | 2009-10-01 | Katholieke Universiteit Leuven | Mucosal gene signatures |
| WO2009150216A1 (en) * | 2008-06-12 | 2009-12-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for predicting the response to a treatment with anakinra |
| ES2335381B1 (es) * | 2008-09-24 | 2011-02-28 | Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron | Metodo in vitro y kit para el pronostico o prediccion de la respuestapor parte de pacientes con artritis reumatoide al tratamiento con agentes bloqueantes del factor tnfalfa. |
| EP2192197A1 (de) * | 2008-11-27 | 2010-06-02 | Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg | Vorhersage der klinischen Reaktion auf die Behandlung mit einem löslichen TNF-Antagonisten oder TNF oder ein TNF-Rezeptoragonist |
| MX2012002766A (es) | 2009-09-03 | 2012-04-02 | Genentech Inc | Metodos para el tratamiento, diagnosis y monitoreo de artritis reumatoide. |
| EP3708190A1 (de) | 2010-02-26 | 2020-09-16 | Novo Nordisk A/S | Stabile, antikörperhaltige zusammensetzungen |
| CA2793137A1 (en) * | 2010-03-24 | 2011-09-29 | Tc Land Expression | Genes and genes combinations predictive of early response or non response of subjects suffering from inflammatory disease to cytokine targeting drugs (cytd) |
| US20130136733A1 (en) | 2010-05-28 | 2013-05-30 | Novo Nordisk A/S | Stable Multi-Dose Compositions Comprising an Antibody and a Preservative |
| CA2827859A1 (en) | 2011-02-28 | 2012-09-07 | Genentech, Inc. | Biological markers and methods for predicting response to b-cell antagonists |
| CN103782172A (zh) * | 2011-07-06 | 2014-05-07 | 雀巢产品技术援助有限公司 | 检测针对使用TNFα的生物疗法的中和性自体抗体的测定法 |
| WO2013117751A2 (en) | 2012-02-10 | 2013-08-15 | Novo Nordisk A/S | Methods related to treatment of inflammatory diseases and disorders |
| HU230680B1 (hu) * | 2012-10-19 | 2017-08-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Diagnosztikai eljárás |
| WO2014134570A1 (en) * | 2013-02-28 | 2014-09-04 | Nodality, Inc. | Compositions and methods for autoimmune disease |
| EP3884276A2 (de) * | 2018-11-23 | 2021-09-29 | Katholieke Universiteit Leuven | Vorhersage einer behandlungsreaktion bei entzündlichen darmerkrankungen |
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| CA2307674C (en) * | 1997-10-30 | 2013-02-05 | Cold Spring Harbor Laboratory | Probe arrays and methods of using probe arrays for distinguishing dna |
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- 2006-05-16 EP EP06290789A patent/EP1857559A1/de not_active Withdrawn
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- 2007-05-15 EP EP07789647A patent/EP2019872B1/de not_active Not-in-force
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- 2007-05-15 US US12/300,847 patent/US7985549B2/en not_active Expired - Fee Related
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- 2007-05-15 WO PCT/IB2007/002373 patent/WO2007135568A2/en active Application Filing
- 2007-05-15 AT AT07789647T patent/ATE530670T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1857559A1 (de) | 2007-11-21 |
| US7985549B2 (en) | 2011-07-26 |
| EP2019872B1 (de) | 2011-10-26 |
| ES2375865T3 (es) | 2012-03-07 |
| WO2007135568A2 (en) | 2007-11-29 |
| DK2019872T3 (da) | 2012-01-16 |
| EP2019872A2 (de) | 2009-02-04 |
| US20090252740A1 (en) | 2009-10-08 |
| WO2007135568A3 (en) | 2008-02-28 |
| ATE530670T1 (de) | 2011-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20150515 |