CA2640151A1 - Compositions and methods for treatment of ophthalmic diseases and disorders - Google Patents
Compositions and methods for treatment of ophthalmic diseases and disorders Download PDFInfo
- Publication number
- CA2640151A1 CA2640151A1 CA002640151A CA2640151A CA2640151A1 CA 2640151 A1 CA2640151 A1 CA 2640151A1 CA 002640151 A CA002640151 A CA 002640151A CA 2640151 A CA2640151 A CA 2640151A CA 2640151 A1 CA2640151 A1 CA 2640151A1
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- CA
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- Prior art keywords
- nr7r8
- retinal
- saturated
- nr7r8r9
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76238406P | 2006-01-26 | 2006-01-26 | |
| US60/762,384 | 2006-01-26 | ||
| PCT/US2007/002330 WO2007089673A2 (en) | 2006-01-26 | 2007-01-26 | Compositions and methods for treatment of ophthalmic diseases and disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2640151A1 true CA2640151A1 (en) | 2007-08-09 |
Family
ID=38327945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002640151A Abandoned CA2640151A1 (en) | 2006-01-26 | 2007-01-26 | Compositions and methods for treatment of ophthalmic diseases and disorders |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090197967A1 (https=) |
| EP (1) | EP1988889A4 (https=) |
| JP (1) | JP2009524684A (https=) |
| CA (1) | CA2640151A1 (https=) |
| WO (1) | WO2007089673A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0810063A2 (pt) | 2007-04-20 | 2014-10-14 | Acucela Inc | Composto, composição farmacêutica, e, métodos para modular fluxo de cromóforo em um ciclo retinóide, para tratar uma doença ou distúrbio oftálmico em um indivíduo, para inibir adaptação ao escuro em uma célula fotorreceptora de bastão da retina, para inibir regeneração de rodopsina em uma célula fotoreceptora de bastão da retina, para reduzir isquemia em um olho de um indivíduo, para inibir neovascularização na retina de um olho de um indivíduo, e para inibir degeneração de uma célula da retina em uma retina |
| NZ601866A (en) | 2007-06-29 | 2013-12-20 | Acucela Inc | Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders |
| US8821870B2 (en) * | 2008-07-18 | 2014-09-02 | Allergan, Inc. | Method for treating atrophic age related macular degeneration |
| MX2011002448A (es) * | 2008-09-05 | 2011-05-25 | Acucela Inc | Compuestos enlazados con azufre para el tratamiento de enfermedades y trastornos oftalmicos. |
| WO2015187942A1 (en) * | 2014-06-04 | 2015-12-10 | Case Western Reserve University | Compositions and methods of treating diabetic retinopathy |
| US10117868B2 (en) * | 2011-10-25 | 2018-11-06 | Case Western Reserve University | Systems pharmacology for treating ocular disorders |
| US10471118B2 (en) * | 2014-05-30 | 2019-11-12 | Case Western Reserve University | Retinylamine derivitives for treatment of ocular disorders |
| WO2016085939A2 (en) * | 2014-11-24 | 2016-06-02 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6437003B1 (en) * | 1997-10-31 | 2002-08-20 | Jean-Baptiste Roullet | Use of retinoids to treat high blood pressure and other cardiovascular disease |
| US20080275134A1 (en) * | 2005-02-24 | 2008-11-06 | University Of Washington | Methods for Treatment of Retinal Degenerative Disease |
-
2007
- 2007-01-26 JP JP2008552479A patent/JP2009524684A/ja active Pending
- 2007-01-26 CA CA002640151A patent/CA2640151A1/en not_active Abandoned
- 2007-01-26 US US12/162,476 patent/US20090197967A1/en not_active Abandoned
- 2007-01-26 EP EP07763005A patent/EP1988889A4/en not_active Withdrawn
- 2007-01-26 WO PCT/US2007/002330 patent/WO2007089673A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1988889A4 (en) | 2009-07-22 |
| WO2007089673A8 (en) | 2008-04-10 |
| WO2007089673A2 (en) | 2007-08-09 |
| EP1988889A2 (en) | 2008-11-12 |
| WO2007089673A3 (en) | 2008-02-28 |
| JP2009524684A (ja) | 2009-07-02 |
| US20090197967A1 (en) | 2009-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |