CA2632782A1 - Antimicrobial cathelicidin peptides - Google Patents
Antimicrobial cathelicidin peptides Download PDFInfo
- Publication number
- CA2632782A1 CA2632782A1 CA002632782A CA2632782A CA2632782A1 CA 2632782 A1 CA2632782 A1 CA 2632782A1 CA 002632782 A CA002632782 A CA 002632782A CA 2632782 A CA2632782 A CA 2632782A CA 2632782 A1 CA2632782 A1 CA 2632782A1
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- Prior art keywords
- polypeptide
- variant
- seq
- nucleic acid
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000032258 transport Effects 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
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- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75487805P | 2005-12-29 | 2005-12-29 | |
| US60/754,878 | 2005-12-29 | ||
| PCT/US2006/049637 WO2007076162A2 (en) | 2005-12-29 | 2006-12-29 | Antimicrobial cathelicidin peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2632782A1 true CA2632782A1 (en) | 2007-07-05 |
Family
ID=38218737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002632782A Abandoned CA2632782A1 (en) | 2005-12-29 | 2006-12-29 | Antimicrobial cathelicidin peptides |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7985832B2 (https=) |
| EP (1) | EP1966235A4 (https=) |
| JP (1) | JP2009521932A (https=) |
| CN (1) | CN101351474A (https=) |
| AU (1) | AU2006330769A1 (https=) |
| BR (1) | BRPI0621148A2 (https=) |
| CA (1) | CA2632782A1 (https=) |
| WO (1) | WO2007076162A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7985832B2 (en) * | 2005-12-29 | 2011-07-26 | Kansas State University Research Foundation | Antimicrobial cathelicidin peptides |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009535027A (ja) * | 2006-04-27 | 2009-10-01 | シンガポール ヘルス サービシーズ ピーティーイー リミテッド | 抗菌ペプチド |
| US8710272B2 (en) | 2007-01-08 | 2014-04-29 | Androscience Corporation | Compounds with (1 E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof |
| US9000222B2 (en) | 2007-01-08 | 2015-04-07 | Androscience Corporation | Compounds with (1E, 6E)-1,7-bis-(3,4-dimethoxyphenyl)-4,4-disubstituted-hepta-1,6-diene-3,5-dione structural scaffold, their biological activity, and uses thereof |
| JP2010515685A (ja) | 2007-01-08 | 2010-05-13 | アンドロサイエンス コーポレーション | （置換フェニル）−プロペナール部分を伴う化合物、その誘導体、生物学的活性およびその使用 |
| CN101820765A (zh) * | 2007-07-31 | 2010-09-01 | 安德鲁科技有限公司 | 包含雄激素受体降解(ard)增强剂的组合物和预防性或治疗性治疗皮肤病与脱发的方法 |
| KR20100057640A (ko) * | 2007-09-11 | 2010-05-31 | 몬도바이오테크 래보래토리즈 아게 | 치료제로서의 인슐린 ｃ-펩티드 단독 또는 ｇｌｐ-1과의 배합물의 용도 |
| WO2009043440A2 (en) * | 2007-09-11 | 2009-04-09 | Mondobiotech Laboratories Ag | Use of il-1 receptor peptide, alone or in combination with d-ala-gln-octadecyl ester, as a therapeutic agent |
| US20120149631A1 (en) * | 2009-06-16 | 2012-06-14 | George Mason Intellectual Properties, Inc | Antimicrobial and antibiofilm activity of cathelicidins |
| US20130079382A1 (en) | 2009-10-12 | 2013-03-28 | Larry J. Smith | Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro |
| US10174081B2 (en) * | 2011-04-21 | 2019-01-08 | George Mason Research Foundation, Inc. | Antimicrobial peptides and uses therefore |
| US11723852B2 (en) | 2011-10-31 | 2023-08-15 | Kane Biotech Inc. | Antimicrobial-antibiofilm compositions and methods of use thereof for personal care products |
| AU2012332014B2 (en) | 2011-10-31 | 2017-01-19 | Kane Biotech Inc. | Compositions and methods for preventing and treating oral diseases |
| US10357470B2 (en) | 2013-03-07 | 2019-07-23 | Kane Biotech Inc. | Antimicrobial-antibiofilm compositions and methods of use thereof |
| MX2016010864A (es) | 2014-02-21 | 2017-05-08 | Avadim Tech Inc | Metodo para el mantenimiento de cateteres uretrales. |
| JP2017519035A (ja) * | 2014-06-27 | 2017-07-13 | ケーン バイオテク インコーポレーテッド | 抗微生物性−抗バイオフィルム性組成物及び該組成物のパーソナルケア製品のための使用 |
| EP3244907B1 (en) | 2015-01-13 | 2020-02-19 | City of Hope | Ctla4-binding protein peptide-linker masks |
| CN104830891B (zh) * | 2015-03-23 | 2017-10-31 | 广东药科大学 | 一种金环蛇抗菌肽Cath‑BF30的高效制备方法 |
| EP3541424A4 (en) * | 2016-11-15 | 2020-10-28 | The Rockefeller University | CHEMERICAL ANTIBODIES INCLUDING BINDING DOMAINS OF PHAGE LYSINES, BACTERIAL AUTOLYSINS, BACTERIOCINS, AND PHAGE TAIL OR PHAGE TAIL FIBRILLES |
| WO2018094403A1 (en) * | 2016-11-21 | 2018-05-24 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Novel antimicrobial and anti-cancer therapy |
| CN109266655B (zh) * | 2018-09-06 | 2021-11-09 | 浙江大学 | 一种抗菌肽及其原核表达方法和应用 |
| CA3143518A1 (en) * | 2019-06-12 | 2020-12-17 | Avadim Health Ip, Inc. | Compositions and methods for the antiseptic cleansing and biofilms treatment of mammalian tissue |
| CN110590927B (zh) * | 2019-09-17 | 2022-06-14 | 济宁医学院 | 多疣壁虎抗氧化肽及其应用 |
| CN111374317B (zh) * | 2019-12-18 | 2022-08-30 | 苏州大学 | 一种天然抗菌肽Hc-CATH在食品防腐保鲜中的应用 |
| CN111374169B (zh) * | 2019-12-18 | 2022-08-30 | 苏州大学 | 一种天然抗菌肽As-CATH5在食品防腐保鲜中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830993A (en) * | 1995-04-10 | 1998-11-03 | Kansas State University Research Foundation | Synthetic antimicrobial peptide |
| US20030022829A1 (en) * | 2001-03-30 | 2003-01-30 | Wendy Maury | Novel antiviral activities primate theta defensins and mammalian cathelicidins |
| US7173007B1 (en) * | 2003-04-02 | 2007-02-06 | The Regents Of The University Of California | Therapy for microbial infections |
| US7776823B2 (en) * | 2003-10-21 | 2010-08-17 | The Regents Of The University Of California | Human cathelicidin antimicrobial peptides |
| WO2005040192A2 (en) * | 2003-10-21 | 2005-05-06 | The Regents Of The University Of California | Human cathelicidin antimicrobial peptides |
| US7485619B2 (en) * | 2005-01-31 | 2009-02-03 | Yeon Sook KIM | Antimicrobial agent |
| KR101326133B1 (ko) * | 2005-03-10 | 2013-11-06 | 삼성디스플레이 주식회사 | 평판 표시 장치 제조 시스템 |
| US8202835B2 (en) * | 2005-06-17 | 2012-06-19 | Yitzchak Hillman | Disease treatment via antimicrobial peptides or their inhibitors |
| JP2009521932A (ja) * | 2005-12-29 | 2009-06-11 | カンザス ステート ユニバーシティー リサーチ ファウンデーション | 抗菌性カテリシジンペプチド |
| JP2010533705A (ja) * | 2007-07-15 | 2010-10-28 | ヒルマン，イチャク | 抗菌ペプチドまたはその阻害剤を用いた疾病治療 |
-
2006
- 2006-12-29 JP JP2008548779A patent/JP2009521932A/ja active Pending
- 2006-12-29 CA CA002632782A patent/CA2632782A1/en not_active Abandoned
- 2006-12-29 CN CNA2006800495652A patent/CN101351474A/zh active Pending
- 2006-12-29 AU AU2006330769A patent/AU2006330769A1/en not_active Abandoned
- 2006-12-29 EP EP06848843A patent/EP1966235A4/en not_active Withdrawn
- 2006-12-29 US US12/087,228 patent/US7985832B2/en not_active Expired - Fee Related
- 2006-12-29 WO PCT/US2006/049637 patent/WO2007076162A2/en not_active Ceased
- 2006-12-29 BR BRPI0621148-8A patent/BRPI0621148A2/pt not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7985832B2 (en) * | 2005-12-29 | 2011-07-26 | Kansas State University Research Foundation | Antimicrobial cathelicidin peptides |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0621148A2 (pt) | 2011-11-29 |
| US7985832B2 (en) | 2011-07-26 |
| AU2006330769A1 (en) | 2007-07-05 |
| US20090221483A1 (en) | 2009-09-03 |
| EP1966235A4 (en) | 2010-01-06 |
| EP1966235A2 (en) | 2008-09-10 |
| WO2007076162A3 (en) | 2008-09-12 |
| JP2009521932A (ja) | 2009-06-11 |
| CN101351474A (zh) | 2009-01-21 |
| WO2007076162A2 (en) | 2007-07-05 |
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