CA2631241C - Materials and methods for treating viral infections with a cysteamine compound - Google Patents

Materials and methods for treating viral infections with a cysteamine compound Download PDF

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Publication number
CA2631241C
CA2631241C CA2631241A CA2631241A CA2631241C CA 2631241 C CA2631241 C CA 2631241C CA 2631241 A CA2631241 A CA 2631241A CA 2631241 A CA2631241 A CA 2631241A CA 2631241 C CA2631241 C CA 2631241C
Authority
CA
Canada
Prior art keywords
cysteamine
influenza
use according
administration
infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2631241A
Other languages
English (en)
French (fr)
Other versions
CA2631241A1 (en
Inventor
Hao Yi Liang
Francis Chi
Qingfu Xu
Bill Piu Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omega-Biopharma (hk) Ltd
Original Assignee
Omega-Biopharma (hk) Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omega-Biopharma (hk) Ltd filed Critical Omega-Biopharma (hk) Ltd
Publication of CA2631241A1 publication Critical patent/CA2631241A1/en
Application granted granted Critical
Publication of CA2631241C publication Critical patent/CA2631241C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA2631241A 2005-11-28 2006-11-28 Materials and methods for treating viral infections with a cysteamine compound Expired - Fee Related CA2631241C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US74058405P 2005-11-28 2005-11-28
US60/740,584 2005-11-28
US81077306P 2006-06-02 2006-06-02
US60/810,773 2006-06-02
US81888506P 2006-07-06 2006-07-06
US60/818,885 2006-07-06
US84702006P 2006-09-25 2006-09-25
US60/847,020 2006-09-25
PCT/US2006/045652 WO2007062272A1 (en) 2005-11-28 2006-11-28 Materials and methods for treating viral infections with a cysteamine compound

Publications (2)

Publication Number Publication Date
CA2631241A1 CA2631241A1 (en) 2007-05-31
CA2631241C true CA2631241C (en) 2014-02-11

Family

ID=37769370

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2631241A Expired - Fee Related CA2631241C (en) 2005-11-28 2006-11-28 Materials and methods for treating viral infections with a cysteamine compound

Country Status (20)

Country Link
US (2) US8415398B2 (https=)
EP (1) EP1954258B8 (https=)
JP (1) JP5138603B2 (https=)
KR (1) KR101440629B1 (https=)
CN (1) CN102038667A (https=)
AP (1) AP2877A (https=)
AR (1) AR057623A1 (https=)
AU (1) AU2006318355B2 (https=)
BR (1) BRPI0619377A2 (https=)
CA (1) CA2631241C (https=)
DK (1) DK1954258T3 (https=)
ES (1) ES2392976T3 (https=)
IL (1) IL191705A (https=)
MX (1) MX2008006851A (https=)
MY (1) MY141003A (https=)
NZ (1) NZ568464A (https=)
PL (1) PL1954258T3 (https=)
PT (1) PT1954258E (https=)
TW (1) TWI401079B (https=)
WO (1) WO2007062272A1 (https=)

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WO2005067899A2 (en) * 2004-01-13 2005-07-28 Omega Bio-Pharma (I.P.2) Limited Methods for treating stress and affecting biological immune systems using a cysteamine compound
AR057623A1 (es) * 2005-11-28 2007-12-05 Omega Bio Pharma H K Ltd Materiales y metodos para el tratamiento de las infecciones virales
EP3659588A1 (en) 2006-01-27 2020-06-03 The Regents of The University of California Enterically coated cysteamine and salts thereof
CN101842092A (zh) * 2007-05-25 2010-09-22 奥碧医药(香港)有限公司 用于治疗流感感染的材料和方法
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WO2010138419A2 (en) * 2009-05-23 2010-12-02 Obio Pharmaceutical (H.K.) Ltd. Materials and methods for treating viral infections
US20120308608A1 (en) * 2010-02-01 2012-12-06 Megan Shaw Interferon-inducing compounds and uses thereof
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US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
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US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
SE1450131A1 (sv) 2011-10-21 2014-05-07 Abbvie Inc DAA-kombinationsbehandling (t.ex. med ABT-072 eller ABT-333)för användning vid behandling av HCV
TWI649100B (zh) 2013-06-17 2019-02-01 地平線罕見醫學製藥有限責任公司 延遲釋放型半胱胺珠粒調配物,以及其製備及使用方法
WO2015038655A1 (en) 2013-09-12 2015-03-19 Alios Biopharma, Inc. Aza-pyridone compounds and uses thereof
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US10143665B2 (en) 2015-11-17 2018-12-04 Horizon Orphan Llc Methods for storing cysteamine formulations and related methods of treatment
JP7418958B2 (ja) 2016-03-17 2024-01-22 チオジェネシス セラピューティクス, インコーポレイテッド システアミンの制御放出のための組成物及びシステアミン感受性障害の全身治療
EA201892448A1 (ru) 2016-04-28 2019-06-28 Эмори Юниверсити Алкинсодержащие нуклеотидные и нуклеозидные терапевтические композиции и связанные с ними способы применения
GB201609940D0 (en) 2016-06-07 2016-07-20 Novabiotics Ltd Microparticles
US10905660B2 (en) * 2016-06-07 2021-02-02 Novabiotics Limited Microparticles
US11758928B2 (en) 2016-12-15 2023-09-19 Société des Produits Nestlé S.A. Compositions and methods that modulate phosphorus or enzymes in a companion animal
JP7208982B2 (ja) 2017-09-20 2023-01-19 チオジェネシス セラピューティクス, インコーポレイテッド システアミン感受性障害の治療方法
EP3866775B1 (en) 2018-10-17 2025-03-19 Novabiotics Limited Cysteamine for use in the treatment of lung diseases
US20230218571A1 (en) * 2020-04-01 2023-07-13 Thiogenesis Therapeutics, Inc. Cysteamine precursor compounds for the treatment of betacoronavirus infections
CA3176642A1 (en) 2020-05-13 2021-11-18 Regents Of The University Of Michigan Cysteamine for the treatment of sars-cov-2 infection
JP2023527038A (ja) * 2020-05-25 2023-06-26 ノバビオティクス・リミテッド 抗ウイルス治療
WO2022040045A1 (en) * 2020-08-18 2022-02-24 New Amsterdam Sciences, Inc. Sod mimetic and methods of using same for the treatment of covid-19
EP4444323A4 (en) * 2021-12-07 2025-12-03 Cila Therapeutic Inc ANTIVIRAL THERAPEUTIC AGENTS AND THEIR USES
WO2024009307A1 (en) * 2022-07-06 2024-01-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Viroporins blockers/inhibitors as anti-flaviviruses agents

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Also Published As

Publication number Publication date
HK1123726A1 (en) 2009-06-26
US20070135525A1 (en) 2007-06-14
AR057623A1 (es) 2007-12-05
EP1954258B1 (en) 2012-09-05
TWI401079B (zh) 2013-07-11
AP2008004511A0 (en) 2008-06-30
KR20080077658A (ko) 2008-08-25
ES2392976T3 (es) 2012-12-17
CA2631241A1 (en) 2007-05-31
NZ568464A (en) 2010-09-30
WO2007062272A1 (en) 2007-05-31
CN102038667A (zh) 2011-05-04
TW200733953A (en) 2007-09-16
US9283198B2 (en) 2016-03-15
AP2877A (en) 2014-03-31
DK1954258T3 (da) 2012-10-15
MX2008006851A (es) 2008-10-09
BRPI0619377A2 (pt) 2011-09-27
US8415398B2 (en) 2013-04-09
IL191705A (en) 2013-11-28
JP2009517395A (ja) 2009-04-30
AU2006318355A1 (en) 2007-05-31
PL1954258T3 (pl) 2013-01-31
JP5138603B2 (ja) 2013-02-06
KR101440629B1 (ko) 2014-09-15
EP1954258A1 (en) 2008-08-13
US20130338113A1 (en) 2013-12-19
AU2006318355B2 (en) 2012-01-12
IL191705A0 (en) 2009-02-11
EP1954258B8 (en) 2012-10-10
MY141003A (en) 2010-02-12
PT1954258E (pt) 2012-10-22

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Effective date: 20191128