CA2630415A1 - Marquage de parties fc pour l'immunocoloration et l'immunociblage - Google Patents
Marquage de parties fc pour l'immunocoloration et l'immunociblage Download PDFInfo
- Publication number
- CA2630415A1 CA2630415A1 CA002630415A CA2630415A CA2630415A1 CA 2630415 A1 CA2630415 A1 CA 2630415A1 CA 002630415 A CA002630415 A CA 002630415A CA 2630415 A CA2630415 A CA 2630415A CA 2630415 A1 CA2630415 A1 CA 2630415A1
- Authority
- CA
- Canada
- Prior art keywords
- molecule
- protein
- targeting
- amino acid
- reactive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72882105P | 2005-10-20 | 2005-10-20 | |
US60/728,821 | 2005-10-20 | ||
PCT/US2006/060127 WO2007048127A2 (fr) | 2005-10-20 | 2006-10-20 | MARQUAGE DE PARTIES Fc POUR L'IMMUNOCOLORATION ET L'IMMUNOCIBLAGE |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2630415A1 true CA2630415A1 (fr) | 2007-04-26 |
Family
ID=37963426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002630415A Abandoned CA2630415A1 (fr) | 2005-10-20 | 2006-10-20 | Marquage de parties fc pour l'immunocoloration et l'immunociblage |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070122408A1 (fr) |
EP (1) | EP1945262A2 (fr) |
JP (1) | JP2009512443A (fr) |
CA (1) | CA2630415A1 (fr) |
WO (1) | WO2007048127A2 (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006116742A2 (fr) * | 2005-04-28 | 2006-11-02 | Ventana Medical Systems, Inc. | Conjugues de nanoparticules |
CA2609702C (fr) * | 2005-04-28 | 2013-05-28 | Ventana Medical Systems, Inc. | Conjugats d'anticorps par lieurs heterobifonctionnels |
JP5199880B2 (ja) * | 2005-11-23 | 2013-05-15 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 分子コンジュゲート |
WO2008134761A2 (fr) * | 2007-04-30 | 2008-11-06 | Intezyne Technologies, Inc. | Modification des groupes de ciblage biologiques pour le traitement du cancer |
EP2214700A4 (fr) * | 2007-11-02 | 2012-08-22 | Janssen Biotech Inc | Produits d'assemblage semi-synthétiques obtenus par fusion de peptide glp-1/fc, procédés et utilisations |
WO2010078376A2 (fr) * | 2008-12-30 | 2010-07-08 | Ventana Medical Systems, Inc. | Anticorps conjugués à un polymère spécifiques de fc et leur utilisation en diagnostic |
WO2010096394A2 (fr) | 2009-02-17 | 2010-08-26 | Redwood Biosciences, Inc. | Véhicules de médicaments à base de protéine marqués par aldéhyde et procédés d'utilisation |
US20110135630A1 (en) * | 2009-07-13 | 2011-06-09 | Tolbert Thomas J | Chemical modification of antibody fragments |
JP6162606B2 (ja) | 2011-01-14 | 2017-07-12 | レッドウッド バイオサイエンス, インコーポレイテッド | アルデヒド−タグ付き免疫グロブリンポリペプチド及びその使用方法 |
EP3610889A1 (fr) * | 2011-05-08 | 2020-02-19 | LegoChem Biosciences, Inc. | Conjugués d'agent actif de protéine et leur procédé de préparation |
WO2013092998A1 (fr) | 2011-12-23 | 2013-06-27 | Innate Pharma | Conjugaison enzymatique d'anticorps |
EP2810069A4 (fr) * | 2012-02-03 | 2015-08-12 | Univ Alberta | Procédé de quantification de bibliothèques de dérivés peptidiques utilisant l'exposition sur phage |
US10132799B2 (en) | 2012-07-13 | 2018-11-20 | Innate Pharma | Screening of conjugated antibodies |
WO2014072482A1 (fr) | 2012-11-09 | 2014-05-15 | Innate Pharma | Etiquettes de reconnaissance pour la conjugaison à médiation par la tgase |
US10611824B2 (en) | 2013-03-15 | 2020-04-07 | Innate Pharma | Solid phase TGase-mediated conjugation of antibodies |
DK2968495T3 (da) * | 2013-03-15 | 2019-10-14 | Daniel J Capon | Hybrid immunoglobulin indeholdende en ikke-peptid-bro |
EP3010547B1 (fr) | 2013-06-20 | 2021-04-21 | Innate Pharma | Conjugaison enzymatique de polypeptides |
KR20160042871A (ko) | 2013-06-21 | 2016-04-20 | 이나뜨 파르마, 에스.아. | 폴리펩티드의 효소적 콘쥬게이션 |
MX2016011934A (es) | 2014-03-14 | 2017-04-13 | J Capon Daniel | Inmunoglobulina hibrida conteniendo un enlace no-peptidilico. |
US10988531B2 (en) | 2014-09-03 | 2021-04-27 | Immunogen, Inc. | Conjugates comprising cell-binding agents and cytotoxic agents |
JP2019515677A (ja) | 2016-04-26 | 2019-06-13 | アール.ピー.シェーラー テクノロジーズ エルエルシー | 抗体複合体ならびにそれを作製および使用する方法 |
WO2021216954A1 (fr) * | 2020-04-23 | 2021-10-28 | Alpha Beta Holdings, Llc | Compositions et méthodes de traitement ou de prévention d'une infection virale |
Family Cites Families (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4215051A (en) * | 1979-08-29 | 1980-07-29 | Standard Oil Company (Indiana) | Formation, purification and recovery of phthalic anhydride |
US4867973A (en) * | 1984-08-31 | 1989-09-19 | Cytogen Corporation | Antibody-therapeutic agent conjugates |
US4699784A (en) * | 1986-02-25 | 1987-10-13 | Center For Molecular Medicine & Immunology | Tumoricidal methotrexate-antibody conjugate |
US5218137A (en) * | 1989-08-29 | 1993-06-08 | Duke University | Light activated acyl-enzymes |
US5114851A (en) * | 1989-08-29 | 1992-05-19 | Duke University | Light activated acyl-enzymes |
JPH05509294A (ja) * | 1990-04-06 | 1993-12-22 | ラ ホヤ キャンサー リサーチ ファウンデーション | 血栓症治療のための方法および組成物 |
JPH06502643A (ja) * | 1990-11-01 | 1994-03-24 | スミスクライン・ビーチャム・コーポレイション | フィブリノーゲン拮抗剤としてのγ−ターンペプチド模倣化合物 |
ES2190428T3 (es) * | 1991-06-28 | 2003-08-01 | Smithkline Beecham Corp | Antagonistas biciclicos de fibrinogeno. |
US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
US5667988A (en) * | 1992-01-27 | 1997-09-16 | The Scripps Research Institute | Methods for producing antibody libraries using universal or randomized immunoglobulin light chains |
GB9225141D0 (en) * | 1992-12-01 | 1993-01-20 | Smithkline Beecham Corp | Chemical compounds |
EP0677043A1 (fr) * | 1992-12-29 | 1995-10-18 | Smithkline Beecham Corporation | Composes inhibant l'aggregation des plaquettes |
US5849736A (en) * | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
US5446056A (en) * | 1993-11-24 | 1995-08-29 | The Du Pont Merck Pharmaceutical Company | Isoxazoline compounds useful as fibrinogen receptor antagonists |
US6403578B1 (en) * | 1993-12-21 | 2002-06-11 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
WO1996006087A1 (fr) * | 1994-08-22 | 1996-02-29 | Smithkline Beecham Corporation | Composes bicycliques |
JPH10510537A (ja) * | 1994-12-13 | 1998-10-13 | スミスクライン・ビーチャム・コーポレイション | 二環式フィブリノーゲン拮抗薬 |
EP0796098A4 (fr) * | 1994-12-22 | 1998-04-29 | Smithkline Beecham Corp | Antagonistes des recepteurs du fibrinogene |
US5795893A (en) * | 1994-12-22 | 1998-08-18 | Smithkline Beecham Corporation | Fibrinogen receptor antagonists |
ZA963391B (en) * | 1995-05-24 | 1997-10-29 | Du Pont Merck Pharma | Isoxazoline fibrinogen receptor antagonists. |
US5780426A (en) * | 1995-06-07 | 1998-07-14 | Ixsys, Incorporated | Fivemer cyclic peptide inhibitors of diseases involving αv β3 |
US5767071A (en) * | 1995-06-07 | 1998-06-16 | Ixsys Incorporated | Sevenmer cyclic peptide inhibitors of diseases involving αv β3 |
US6008213A (en) * | 1995-06-29 | 1999-12-28 | Smithkline Beecham Corporation | Integrin receptor antagonists |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
ES2161373T3 (es) * | 1995-08-30 | 2001-12-01 | Searle & Co | Derivados de meta-guanidina, urea, tiourea o acido azaciclico-aminobenzoico como antagonistas de integrinas. |
US5760028A (en) * | 1995-12-22 | 1998-06-02 | The Dupont Merck Pharmaceutical Company | Integrin receptor antagonists |
EP0906103A1 (fr) * | 1995-12-29 | 1999-04-07 | Smithkline Beecham Corporation | Antagonistes du recepteur de la vitronectine |
AU2323897A (en) * | 1996-03-29 | 1997-10-22 | G.D. Searle & Co. | Cyclopropyl alkanoic acid derivatives |
CA2250690A1 (fr) * | 1996-03-29 | 1997-10-09 | G.D. Searle & Co. | Derives de l'acide cinnamique et leur utilisation comme antagonistes de l'integrine |
ATE212978T1 (de) * | 1996-03-29 | 2002-02-15 | Searle & Co | Para-substituierte phenylpropansäure derivate als integrin-antagonisten |
EP0889876B1 (fr) * | 1996-03-29 | 2001-07-25 | G.D. SEARLE & CO. | Derives meta-substitues du sulphonamide de phenylene |
GB9608510D0 (en) * | 1996-04-25 | 1996-07-03 | Medical Res Council | Calcium dependent binding ligands |
DE19629816A1 (de) * | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
US6211184B1 (en) * | 1996-08-29 | 2001-04-03 | Merck & Co., Inc. | Integrin antagonists |
US5981546A (en) * | 1996-08-29 | 1999-11-09 | Merck & Co., Inc. | Integrin antagonists |
NZ334438A (en) * | 1996-09-03 | 2000-10-27 | Smithkline Beecham Corp | (S)-7-[(4,4'-bipiperidrin-1-yl)carbonyl]-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetic acid hydrochloride as a platelet aggregation inhibitor |
KR19990076764A (ko) * | 1996-10-25 | 1999-10-15 | 히라타 다다시 | 래디시콜 유도체 |
US5952341A (en) * | 1996-10-30 | 1999-09-14 | Merck & Co., Inc. | Integrin antagonists |
US6218387B1 (en) * | 1996-12-20 | 2001-04-17 | Hoechst Aktiengesellschaft | Vitronectin receptor anatagonists, their preparation and their use |
DE19653647A1 (de) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung |
DE19653645A1 (de) * | 1996-12-20 | 1998-06-25 | Hoechst Ag | Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung |
CO4920232A1 (es) * | 1997-01-08 | 2000-05-29 | Smithkline Beecham Corp | Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin |
US6017925A (en) * | 1997-01-17 | 2000-01-25 | Merck & Co., Inc. | Integrin antagonists |
US6088213A (en) * | 1997-07-11 | 2000-07-11 | Applied Materials, Inc. | Bipolar electrostatic chuck and method of making same |
US6239138B1 (en) * | 1997-07-25 | 2001-05-29 | Smithkline Beecham Corporation | Vitronectin receptor antagonist |
US6066648A (en) * | 1997-12-17 | 2000-05-23 | Merck & Co., Inc. | Integrin receptor antagonists |
US6028087A (en) * | 1998-01-21 | 2000-02-22 | Smithkline Beecham Corporation | Platelet aggregation inhibiting compounds |
US6313119B1 (en) * | 1998-01-23 | 2001-11-06 | Adventis Pharma Deutschland Gmbh | Sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion |
US6172256B1 (en) * | 1998-03-04 | 2001-01-09 | G.D. Searle & Co. | Chiral-β-amino acid compounds and derivatives thereof |
US6281331B1 (en) * | 1998-03-23 | 2001-08-28 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
IL138093A0 (en) * | 1998-03-31 | 2001-10-31 | Du Pont Pharm Co | Pharmaceuticals for the imaging of angiogenic disorders |
US6140081A (en) * | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
US6319937B1 (en) * | 1998-11-18 | 2001-11-20 | Dupont Pharmaceuticals Company | Isoxazoline fibrinogen receptor antagonists |
EP1150965A4 (fr) * | 1999-02-03 | 2002-05-15 | Merck & Co Inc | Derives de la benzazepine utilises comme antagonistes du recepteur alpha-v de l'integrine |
EP1028114A1 (fr) * | 1999-02-13 | 2000-08-16 | Aventis Pharma Deutschland GmbH | Nouveaux dérivés de guanidine et leur utilisation comme inhibiteurs de l'adhésion des cellules |
JP2003510360A (ja) * | 1999-10-04 | 2003-03-18 | メルク エンド カムパニー インコーポレーテッド | インテグリン受容体拮抗薬 |
EP1446418B1 (fr) * | 2001-10-22 | 2012-05-23 | The Scripps Research Institute | Composes de ciblage de l'integrine |
WO2003059251A2 (fr) * | 2001-10-22 | 2003-07-24 | The Scripps Research Institute | Composes de ciblage d'anticorps |
EP2341134B1 (fr) * | 2003-01-31 | 2014-08-27 | Promega Corporation | Fixation covalente de groupes fonctionnels à des protéines |
AU2004282984B2 (en) * | 2003-11-13 | 2011-07-14 | Hanmi Science Co., Ltd. | Protein complex using immunoglobulin fragment andmethod for the preparation thereof |
WO2006069246A2 (fr) * | 2004-12-22 | 2006-06-29 | Ambrx, Inc. | Compositions contenant des acides amines non naturels et des polypeptides, procedes impliquant ces acides amines non naturels et polypeptides, et utilisations desdits acides amines non naturels et polypeptides |
US8008453B2 (en) * | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
EP2069396B1 (fr) * | 2006-09-08 | 2015-10-21 | Ambrx, Inc. | Polypeptide plasmatique humain modifie ou squelettes de fc et leurs utilisations |
-
2006
- 2006-10-20 CA CA002630415A patent/CA2630415A1/fr not_active Abandoned
- 2006-10-20 US US11/551,665 patent/US20070122408A1/en not_active Abandoned
- 2006-10-20 JP JP2008536644A patent/JP2009512443A/ja not_active Ceased
- 2006-10-20 WO PCT/US2006/060127 patent/WO2007048127A2/fr active Application Filing
- 2006-10-20 EP EP06839495A patent/EP1945262A2/fr not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP1945262A2 (fr) | 2008-07-23 |
WO2007048127A9 (fr) | 2007-06-07 |
WO2007048127A3 (fr) | 2008-10-23 |
WO2007048127A2 (fr) | 2007-04-26 |
US20070122408A1 (en) | 2007-05-31 |
JP2009512443A (ja) | 2009-03-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |